Inclusion of Gene-Gene and Gene-Environment Interactions Unlikely to Dramatically Improve Risk Prediction for Complex Diseases

The American Journal of Human Genetics - Tập 90 - Trang 962-972 - 2012
Hugues Aschard1,2, Jinbo Chen3, Marilyn C. Cornelis4, Lori B. Chibnik5, Elizabeth W. Karlson6, Peter Kraft1,2,7
1Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
2Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115 USA
3Department of Biostatistics, University of Pennsylvania, Philadelphia, PA 19104, USA
4Department of Nutrition Harvard School of Public Health Boston, MA 02115 USA
5Department of Neurology, Brigham and Women’s Hospital, Boston, MA 02115, USA
6Department of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Boston, MA 02115, USA
7Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA

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