Incidence of antimicrobial resistance among Enterobacteriaceae isolated in Riyadh
Tóm tắt
The antimicrobial resistance of 1,018 isolates of Enterobacteriaceae isolated from fecal specimens of the urban population of Riyadh, Saudi Arabia, was studied. Resistance to 1 or more of 10 antimicrobial agents was encountered in 50.2% of the isolates. Of the isolates tested,Escherichia coli (0.8%) andKlebsiella species (1.6%) were found resistant to seven antimicrobial agents simultaneously: ampicillin, chloramphenicol, kanamycin, colistin, streptomycin, tetracycline, and carbenicillin. Resistance to nalidixic acid was encountered in only 0.68% of theE. coli isolates. No isolate was found to be resistant to gentamicin. Eighty-six of the resistant strains were tested for their ability to transfer their resistance. Forty percent were able to do so withE. coli K-12.
Tài liệu tham khảo
Al-Sowaygh, I. A. 1971. Piliation and fertility of enteric bacteria carrying R and F factors. Ph.D. thesis. University of Southampton.
Anderson, E. S. 1968. The ecology of transferable drug resistance in the enterobacteria. Annual Review of Microbiology22:131–152.
Bauer, A. W., Kirby, W. M. M., Sherris, J. C., Turck, M. 1966. Antibiotic susceptibility testing by a standardized single disk method. American Journal of Clinical Pathology45:493–496.
Byers, P. A., Dupont, H. L., Goldschmidt, M. C. 1976. Antimicrobial susceptibilities of shigellae isolated in Houston, Texas, in 1974. Antimicrobial Agents and Chemotherapy9:288–291.
Chun, D., Seol, S. Y., Cho, D. T., Tak, R. 1977. Drug resistance and R plasmids inSalmonella typhi isolated in Korea. Antimicrobial Agents and Chemotherapy11:209–213.
Datta, N. 1973. Transmissible antibiotic resistance, pp. 31–40. In: Geddes, A. M., Williams, J. D. (eds.), Current antibiotic therapy. Edinburgh, London: Churchill Livingstone.
Davis, C. E., Anandan, J. 1970. The evaluation of R-factor: A study of a pre-antibiotic community in Borneo. New England Journal of Medicine282:117–119.
Falkow, S. 1975. Infectious multiple drug resistance. London: Pion.
Farrar, W. E., Edison, M. 1971. Antibiotic resistance inShigella mediated by R-factors. Journal of Infectious Diseases123:477–501.
Guinée, P., Ugueto, N., van Leeuwen, N. 1970.Escherichia coli with resistance factors in vegetarians, babies and non-vegetarians. Applied Microbiology20:531–536.
Hocmanová, M., Krčméry, V. 1974. Occurrence of a seven-drug-resistance plasmid in two strains ofSalmonella typhimurium from diarrheatic patients. Zentralblatt für Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene, Abt. 1 Orig., Reihe A229:277–278.
Laufs, R., Kleimann, F. 1978. Antibiotic resistance factors and other plasmids in bacterial isolates from hospitalized patients. Zentralblatt für Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene, Abt. 1 Orig., Reihe A240:503–516.
Mare, I. J. 1968. Incidence of R-factors among gram-negative bacteria in drug-free human and animal communities. Nature220:1046–1047.
Mitsuhashi, S. 1977. R-factor: Drug resistance plasmid. Baltimore, London, Tokyo: University Park Press.
Neu, H. C., Cherubin, C. E., Longo, E. D., Winter, J. 1975. Antimicrobial resistance of Shigella isolated in New York City in 1973. Antimicrobial Agents and Chemotherapy7:833–835.
Rennie, R. P., Duncan, I. B. R. 1977. Emergence of gentamicin-resistantKlebsiella in a general hospital. Antimicrobial Agents and Chemotherapy11:179–184.
Richmond, M. H. 1975. R factors in man and his environment, pp. 27–35. In: Schlessinger, D. (ed.), Microbiology—1974. Washington, D. C.: American Society for Microbiology.
Slocombe, B., Sutherland, R. 1973. Transferable antibiotic resistance in enteropathogenicEscherichia coli between 1948 and 1968. Antimicrobial Agents and Chemotherapy4:459–466.
Tanaka, T., Tsunoda, M., Mitsuhashi, S. 1975. Drug resistance inShigella strains isolated in Japan from 1965 to 1973, pp. 187–199. In: Mitsuhashi, S., Hashimoto, H. (eds.), Microbial drug resistance. Baltimore, London, Tokyo: University Park Press.
Watanabe, T. 1963. Infective heredity of multiple drug resistance in bacteria. Bacteriological Reviews27:87–115.
Watanabe, T. 1971. Infectious drug resistance in bacteria. Current Topics in Microbiology and Immunology56:43–98.