In vivo assessment and potential diagnosis of xenobiotics that perturb the thyroid pathway: Proteomic analysis of Xenopus laevis brain tissue following exposure to model T4 inhibitors

Jose Serrano1, LeeAnn Higgins2, Bruce A. Witthuhn2, Lorraine B. Anderson2, Todd Markowski2, Gary W. Holcombe1, Patricia A. Kosian1, Joseph J. Korte1, Joseph E. Tietge1, Sigmund J. Degitz1
1U.S. Environmental Protection Agency, Office of Research and Development, National Health and Environmental Effects Research Laboratory, Mid-Continent Ecology Division, Duluth, MN 55804, USA
2University of Minnesota, Department of Biochemistry, Molecular Biology and Biophysics, St Paul, MN 55119, USA