In-vitro spin-trapping of free radicals produced during trichloroethylene and diethylether metabolism

Perkins, 1980, Spin trapping, Adv. Phys. Org. Chem., 17, 1, 10.1016/S0065-3160(08)60127-6 Aurian-Blajeni, 1982, Radical generation during the illumination of aqueous suspension of tungsten in presence of methanol, sodium formate: detection by spin-trapping, Photochem. Photobiol., 35, 157, 10.1111/j.1751-1097.1982.tb03825.x Makino, 1983, Chemical effects of ultrasound on aqueous solutions: formation of hydroxyl radicals and hydrogen atoms, J. Phys. Chem., 87, 1369, 10.1021/j100231a020 Rosenthal, 1981, Sonolysis of perhalomethane as studied by EPR and spin-trapping, J. Magnet. Res., 45, 359 Janzen, 1980, Vol. 4, 11 Kudo, 1983, ESR spin-trap and U.V. investigations of solutions of d-glucose and lactose irradiated with ultrasound, Carbohydr. Res., 123, 41, 10.1016/0008-6215(83)88379-7 Sampath, 1985, Prooxidant effects of glutathione in aerobic hemoglobin solutions: Superoxide generation from uncoordinated dioxygen, J. Am. Chem. Soc., 107, 4076, 10.1021/ja00299a053 Saprin, 1977, Spin-trapping and its application in the study of lipid peroxidation and free-radical production with liver microsomes, Arch. Biochem. Biophys., 180, 480, 10.1016/0003-9861(77)90063-7 Poyer, 1978, Spin-trapping of the trichloromethyl radical produced during enzymatic NADPH oxidation in the presence of carbon tetrachloride or bromotrichloromethane, Biochim. Biophys. Acta, 539, 402, 10.1016/0304-4165(78)90044-2 Poyer, 1980, Confirmation of assignment of the trichloromethyl radical spin adduct detected by spin-trapping during C13-carbon tetrachloride metabolism in vitro and in vivo, Biochem. Biophys. Res. Commun., 94, 1154, 10.1016/0006-291X(80)90540-9 Chignell, 1985, Structure activity relationships in the free-radical metabolism of xenobiotics, Environ. Health Perspect., 61, 133, 10.1289/ehp.8561133 Kjellstrand, 1980, Irreversible effects of trichloroethylene exposure on the central nervous system, Scand. J. Work Environ. Health, 6, 40, 10.5271/sjweh.2635 Westergren, 1984, Reduction of brain specific gravity in mice prenatally exposed to trichloroethylene, Toxicol. Lett., 23, 223, 10.1016/0378-4274(84)90130-9 Buben, 1985, Delineation of the role of metabolism in the hepatotoxicity of trichloroethylene: a dose-effect study, Toxicol. Appl. Pharmacol., 78, 105, 10.1016/0041-008X(85)90310-2 Leighty, 1981, In vitro conjugation of the trichloroethylene metabolite trichloroethanol to a fatty acid, A.F. Res. Commun. Chem. Pathol. Pharmacol., 32, 569 Kyrklund, 1986, Fatty acid changes in rat brain ethanolamine phosphoglycerides during and following chronic exposure to trichloroethylene, Toxicol. Appl. Pharmacol., 85, 145, 10.1016/0041-008X(86)90108-0 Bonse, 1976, Chemical reactivity, biotransformation and toxicity of polychlorinated aliphatic compounds, C.R.C. Crit. Rev. Toxicol., 10, 395, 10.1080/10408447609164019 Henschler, 1977, Metabolic activation of chlorinated ethylenes: dependence of mutagenic effect on electrophilic reactivity of the metabolically formed epoxides, Arch. Toxicol., 39, 7, 10.1007/BF00343270 Ertle, 1972, Metabolism of trichloroethanol. 1. The significance of trichloroethanol in long term exposure conditions, Arch. Toxicol., 29, 171, 10.1007/BF00315598 Derobert, 1958, 754 Krikun, 1984, Increased microsomal oxidation of ethanol by cytochrome P 450 and hydroxyl-dependent pathways after chronic ethanol consumption, J. Biochem. Pharmacol., 33, 3306, 10.1016/0006-2952(84)90097-2 Smith, 1985, Free radicals and alcoholics, Lancet, 2, 774, 10.1016/S0140-6736(85)90647-6 Fink, 1985, Increased free radical activity in alcoholics, Lancet, 2, 291, 10.1016/S0140-6736(85)90347-2 Finkelstein, 1980, Spin-trapping of superoxide and hydroxyl radicals: practical aspects, Arch. Biochem. Biophys., 200, 1, 10.1016/0003-9861(80)90323-9 Jangen, 1978, Spin trapping with α-pyridyl 1-oxide-N-tert-butyl nitrones in aqueous solutions: a unique electron spin resonance spectrum for the hydroxyl radical adduct, J. Am. Chem. Soc., 100, 2923, 10.1021/ja00477a075 Schenkman, 1978, Preparation of microsomes with calcium, Meth. Enzymol., 52, 83, 10.1016/S0076-6879(78)52008-9 Gornall, 1985, J. Biol. Chem., 177, 751, 10.1016/S0021-9258(18)57021-6 Derache, 1980, Radicaux libres, lipoperoxidation et toxicité, R. Ann. Nutr. Alim., 34, 599 Kappus, 1981, Toxic drug effects associated with oxygen metabolism redox cycling and lipid peroxidation, Experientia, 37, 1233, 10.1007/BF01948335