In vitro responses of chicken macrophage-like monocytes following exposure to pathogenic and non-pathogenic E. coli ghosts loaded with a rational design of conserved genetic materials of influenza and Newcastle disease viruses

Alvarez, 2013, Antigen targeting to APC: from mice to veterinary species, Dev. Comp. Immunol., 41, 153, 10.1016/j.dci.2013.04.021 Blackburn, 2007, IL-10, T cell exhaustion and viral persistence, Trends Microbiol., 15, 143, 10.1016/j.tim.2007.02.006 Brooks, 2008, IL-10 blockade facilitates DNA vaccine-induced T cell responses and enhances clearance of persistent virus infection, J. Exp. Med., 205, 533, 10.1084/jem.20071948 Brown, 2009, Prospects for an influenza vaccine that induces cross-protective cytotoxic T lymphocytes, Immunol. Cell Biol., 87, 300, 10.1038/icb.2009.16 Chambers, 1988, Location of a neutralizing epitope for the haemagglutinin-neuraminidase glycoprotein of Newcastle disease virus, J. Gen. Virol., 69, 2115, 10.1099/0022-1317-69-8-2115 Chmielewski, 2011, Avian influenza: public health and food safety concerns, Annu. Rev. Food Sci. Technol., 2, 37, 10.1146/annurev-food-022510-133710 de la Barrera, 2004, IL-10 down-regulates costimulatory molecules on Mycobacterium tuberculosis-pulsed macrophages and impairs the lytic activity of CD4 and CD8CTL in tuberculosis patients, Clin. Exp. Immunol., 138, 128, 10.1111/j.1365-2249.2004.02577.x Dinarello, 2000, Proinflammatory cytokines, Chest, 118, 503, 10.1378/chest.118.2.503 Epstein, 2003, Control of influenza virus infection by immunity to conserved viral features, Expert Rev. Anti-infect. Ther., 1, 627, 10.1586/14787210.1.4.627 Fajardo-Moser, 2008, Mechanisms of dendritic cell-based vaccination against infection, Int. J. Med. Microbiol. IJMM, 298, 11, 10.1016/j.ijmm.2007.07.003 Fuss, 2009, Isolation of whole mononuclear cells from peripheral blood and cord blood Genovese, 2013, The avian heterophil, Dev. Comp. Immunol., 41, 334, 10.1016/j.dci.2013.03.021 Gilbert, 2013, Advances in the development of universal influenza vaccines, Influenza Other Respir. Viruses, 7, 750, 10.1111/irv.12013 Grimm, 2013, Vaccine design: emerging concepts and renewed optimism, Curr. Opin. Biotechnol., 24, 1078, 10.1016/j.copbio.2013.02.015 Haidinger, 2003, Escherichia coli ghost production by expression of lysis gene e and staphylococcal nuclease, Appl. Environ. Microbiol., 69, 6106, 10.1128/AEM.69.10.6106-6113.2003 Hong, 2006, Molecular cloning and characterization of chicken lipopolysaccharide-induced TNF-alpha factor (LITAF), Dev. Comp. Immunol., 30, 919, 10.1016/j.dci.2005.12.007 Jechlinger, 2006, Optimization and delivery of plasmid DNA for vaccination, Expert Rev. Vaccines, 5, 803, 10.1586/14760584.5.6.803 Kapczynski, 2013, Immune responses of poultry to Newcastle disease virus, Dev. Comp. Immunol., 41, 447, 10.1016/j.dci.2013.04.012 Kawaoka, 2012, Influenza viruses: an introduction, Methods Mol. Biol., 865, 1, 10.1007/978-1-61779-621-0_1 Kohlmeier, 2009, Immunity to respiratory viruses, Annu. Rev. Immunol., 27, 61, 10.1146/annurev.immunol.021908.132625 Koller, 2013, Modulation of bacterial ghosts–induced nitric oxide production in macrophages by bacterial ghost-delivered resveratrol, FEBS J., 280, 1214, 10.1111/febs.12112 Langemann, 2010, The bacterial ghost platform system: production and applications, Bioeng. Bugs, 1, 326, 10.4161/bbug.1.5.12540 Magor, 2013, Defense genes missing from the flight division, Dev. Comp. Immunol., 41, 377, 10.1016/j.dci.2013.04.010 Mayr, 2005, Bacterial ghosts as antigen delivery vehicles, Adv. Drug Deliv. Rev., 57, 1381, 10.1016/j.addr.2005.01.027 Miller, 2013, Effects of Newcastle disease virus vaccine antibodies on the shedding and transmission of challenge viruses, Dev. Comp. Immunol., 41, 505, 10.1016/j.dci.2013.06.007 Montosi, 2000, Wild-type HFE protein normalizes transferrin iron accumulation in macrophages from subjects with hereditary hemochromatosis, Blood, 96, 1125, 10.1182/blood.V96.3.1125 Muhammad, 2012, Bacterial ghosts as carriers of protein subunit and DNA-encoded antigens for vaccine applications, Expert Rev. Vaccines, 11, 97, 10.1586/erv.11.149 Noh, 2013, Influenza vaccines: unmet needs and recent developments, Infect. Chemother., 45, 375, 10.3947/ic.2013.45.4.375 Park, 2007, Functional characterization of tumor necrosis factor superfamily 15 (TNFSF15) induced by lipopolysaccharides and Eimeria infection, Dev. Comp. Immunol., 31, 934, 10.1016/j.dci.2006.12.010 Park, 2011, Complete protection against a H5N2 avian influenza virus by a DNA vaccine expressing a fusion protein of H1N1HA and M2e, Vaccine, 29, 5481, 10.1016/j.vaccine.2011.05.062 Paukner, 2005, DNA-loaded bacterial ghosts efficiently mediate reporter gene transfer and expression in macrophages, Mol. Ther. J. Am. Soc. Gene Ther., 11, 215, 10.1016/j.ymthe.2004.09.024 Pfaffl, 2001, A new mathematical model for relative quantification in real-time RT-PCR, Nucleic Acids Res., 29, e45, 10.1093/nar/29.9.e45 Pica, 2013, Toward a universal influenza virus vaccine: prospects and challenges, Annu. Rev. Med., 64, 189, 10.1146/annurev-med-120611-145115 Redding, 2009, DNA vaccines in veterinary use, Expert Rev. Vaccines, 8, 1251, 10.1586/erv.09.77 Schijns, 2011, Trends in vaccine adjuvants, Expert Rev. Vaccines, 10, 539, 10.1586/erv.11.21 Schultz-Cherry, 2010, Influenza vaccines: the good, the bad, and the eggs, Adv. Virus Res., 77, 63, 10.1016/B978-0-12-385034-8.00003-X Steinhauer, 2002, Genetics of influenza viruses, Annu. Rev. Genet., 36, 305, 10.1146/annurev.genet.36.052402.152757 Stewart, 2013, Potential directions for chicken immunology research, Dev. Comp. Immunol., 41, 463, 10.1016/j.dci.2013.05.011 Tabrizi, 2004, Bacterial ghosts–biological particles as delivery systems for antigens, nucleic acids and drugs, Curr. Opin. Biotechnol., 15, 530, 10.1016/j.copbio.2004.10.004 Tuntufye, 2012, Escherichia coli ghosts or live E. coli expressing the ferri-siderophore receptors FepA, FhuE, IroN and IutA do not protect broiler chickens against avian pathogenic E. coli (APEC), Vet. Microbiol., 159, 470 Vilte, 2012, A systemic vaccine based on Escherichia coli O157:H7 bacterial ghosts (BGs) reduces the excretion of E. coli O157:H7 in calves, Vet. Immunol. Immunopathol., 146, 169, 10.1016/j.vetimm.2012.03.002 Wigley, 2013, Immunity to bacterial infection in the chicken, Dev. Comp. Immunol., 41, 413, 10.1016/j.dci.2013.04.008 Williams, 2009, Plasmid DNA vaccine vector design: impact on efficacy, safety and upstream production, Biotechnol. Adv., 27, 353, 10.1016/j.biotechadv.2009.02.003 Witte, 1990, Endogenous transmembrane tunnel formation mediated by phi X174 lysis protein E, J. Bacteriol., 172, 4109, 10.1128/jb.172.7.4109-4114.1990 Zhao, 2005, Development of a candidate vaccine for Newcastle disease virus by epitope display in the Cucumber mosaic virus capsid protein, Biotechnol. Lett., 27, 375, 10.1007/s10529-005-1773-2