In vitro models for accurate prediction of renal tubular xenobiotic transport in vivo
Tài liệu tham khảo
Morrissey, 2013, Renal transporters in drug development, Annu Rev Pharmacol Toxicol, 53, 503, 10.1146/annurev-pharmtox-011112-140317
Cook, 2014, Lessons learned from the fate of astrazeneca's drug pipeline: a five-dimensional framework, Nat Rev Drug Discov, 13, 419, 10.1038/nrd4309
Ghane Shahrbaf, 2015, Drug-induced renal disorders, J Ren Inj Prev, 4, 57
Awdishu, 2017, The 6r's of drug induced nephrotoxicity, BMC Nephrol, 18, 124, 10.1186/s12882-017-0536-3
Paul, 2010, How to improve r&d productivity: the pharmaceutical industry's grand challenge, Nat Rev Drug Discov, 9, 203, 10.1038/nrd3078
Magee, 2013, Discovery of dap-3 polymyxin analogues for the treatment of multidrug-resistant gram-negative nosocomial infections, J Med Chem, 56, 5079, 10.1021/jm400416u
2020
2012
2018
Parvez, 2017, Evaluation of para-aminosalicylic acid as a substrate of multiple solute carrier uptake transporters and possible drug interactions with nonsteroidal anti-inflammatory drugs in vitro, Antimicrob Agents Chemother, 61, 10.1128/AAC.02392-16
Muller, 2017, Contribution of mate1 to renal secretion of the nmda receptor antagonist memantine, Mol Pharm, 14, 2991, 10.1021/acs.molpharmaceut.7b00179
Hotchkiss, 2015, Organic anion transporter 2 transcript variant 1 shows broad ligand selectivity when expressed in multiple cell lines, Front Pharmacol, 6, 216, 10.3389/fphar.2015.00216
Li, 2013, Kinetic analysis of human and canine p-glycoprotein-mediated drug transport in mdr1-mdck cell model: approaches to reduce false-negative substrate classification, J Pharmaceut Sci, 102, 3436, 10.1002/jps.23523
Tahara, 2008, Directional transcellular transport of bisoprolol in p-glycoprotein-expressed llc-ga5-col150 cells, but not in renal epithelial llc-pk1 cells, Drug Metabol Pharmacokinet, 23, 340, 10.2133/dmpk.23.340
Jenkinson, 2012, The limitations of renal epithelial cell line hk-2 as a model of drug transporter expression and function in the proximal tubule, Pflügers Archiv, 464, 601, 10.1007/s00424-012-1163-2
Wilmer, 2010, Novel conditionally immortalized human proximal tubule cell line expressing functional influx and efflux transporters, Cell Tissue Res, 339, 449, 10.1007/s00441-009-0882-y
Jansen, 2015, Human proximal tubule epithelial cells cultured on hollow fibers: living membranes that actively transport organic cations, Sci Rep, 5, 16702, 10.1038/srep16702
Jansen, 2014, A morphological and functional comparison of proximal tubule cell lines established from human urine and kidney tissue, Exp Cell Res, 323, 87, 10.1016/j.yexcr.2014.02.011
Secker, 2019, Functional transepithelial transport measurements to detect nephrotoxicity in vitro using the rptec/tert1 cell line, Arch Toxicol, 93, 1965, 10.1007/s00204-019-02469-8
Nieskens, 2016, A human renal proximal tubule cell line with stable organic anion transporter 1 and 3 expression predictive for antiviral-induced toxicity, AAPS J, 18, 465, 10.1208/s12248-016-9871-8
Nieskens, 2018, Expression of organic anion transporter 1 or 3 in human kidney proximal tubule cells reduces cisplatin sensitivity, Drug Metab Dispos, 46, 592, 10.1124/dmd.117.079384
Kuteykin-Teplyakov, 2010, Differences in the expression of endogenous efflux transporters in mdr1-transfected versus wildtype cell lines affect p-glycoprotein mediated drug transport, Br J Pharmacol, 160, 1453, 10.1111/j.1476-5381.2010.00801.x
Jonker, 2003, Deficiency in the organic cation transporters 1 and 2 (oct1/oct2 [slc22a1/slc22a2]) in mice abolishes renal secretion of organic cations, Mol Cell Biol, 23, 7902, 10.1128/MCB.23.21.7902-7908.2003
Yonezawa, 2011, Importance of the multidrug and toxin extrusion mate/slc47a family to pharmacokinetics, pharmacodynamics/toxicodynamics and pharmacogenomics, Br J Pharmacol, 164, 1817, 10.1111/j.1476-5381.2011.01394.x
Basit, 2019, Kidney cortical transporter expression across species using quantitative proteomics, Drug Metab Dispos, 47, 802, 10.1124/dmd.119.086579
Brown, 2008, Characterisation of human tubular cell monolayers as a model of proximal tubular xenobiotic handling, Toxicol Appl Pharmacol, 233, 428, 10.1016/j.taap.2008.09.018
Sanchez-Romero, 2020, A simple method for the isolation and detailed characterization of primary human proximal tubule cells for renal replacement therapy, Int J Artif Organs, 43, 45, 10.1177/0391398819866458
Bajaj, 2020, Freshly isolated primary human proximal tubule cells as an in vitro model for the detection of renal tubular toxicity, Toxicology, 442, 152535, 10.1016/j.tox.2020.152535
Bartels, 2020, Review of the pharmacokinetics and metabolism of triclopyr herbicide in mammals: impact on safety assessments, Regul Toxicol Pharmacol, 116, 104714, 10.1016/j.yrtph.2020.104714
Little, 2019, Generating kidney from stem cells, Annu Rev Physiol, 81, 335, 10.1146/annurev-physiol-020518-114331
Takasato, 2015, Kidney organoids from human ips cells contain multiple lineages and model human nephrogenesis, Nature, 526, 564, 10.1038/nature15695
Hiratsuka, 2019, Induction of human pluripotent stem cells into kidney tissues by synthetic mrnas encoding transcription factors, Sci Rep, 9, 913, 10.1038/s41598-018-37485-8
Bajaj, 2018, Human pluripotent stem cell-derived kidney model for nephrotoxicity studies, Drug Metab Dispos, 46, 1703, 10.1124/dmd.118.082727
Czerniecki, 2018, High-throughput screening enhances kidney organoid differentiation from human pluripotent stem cells and enables automated multidimensional phenotyping, Cell Stem Cell, 22, 929, 10.1016/j.stem.2018.04.022
Garreta, 2019, Fine tuning the extracellular environment accelerates the derivation of kidney organoids from human pluripotent stem cells, Nat Mater, 18, 397, 10.1038/s41563-019-0287-6
Schutgens, 2019, Tubuloids derived from human adult kidney and urine for personalized disease modeling, Nat Biotechnol, 37, 303, 10.1038/s41587-019-0048-8
Soo, 2018, Advances in predictive in vitro models of drug-induced nephrotoxicity, Nat Rev Nephrol, 14, 378, 10.1038/s41581-018-0003-9
Wilmer, 2016, Kidney-on-a-chip technology for drug-induced nephrotoxicity screening, Trends Biotechnol, 34, 156, 10.1016/j.tibtech.2015.11.001
Orosz, 2004, Growth, immortalization, and differentiation potential of normal adult human proximal tubule cells, In Vitro Cell Dev Biol Anim, 40, 22, 10.1290/1543-706X(2004)40<22:GIADPO>2.0.CO;2
Kaminski, 2016, Direct reprogramming of fibroblasts into renal tubular epithelial cells by defined transcription factors, Nat Cell Biol, 18, 1269, 10.1038/ncb3437
Jang, 2013, Human kidney proximal tubule-on-a-chip for drug transport and nephrotoxicity assessment, Integr Biol (Camb), 5, 1119, 10.1039/c3ib40049b
Homan, 2016, Bioprinting of 3d convoluted renal proximal tubules on perfusable chips, Sci Rep, 6, 34845, 10.1038/srep34845
Lin, 2019, Renal reabsorption in 3d vascularized proximal tubule models, Proc Natl Acad Sci U S A, 116, 5399, 10.1073/pnas.1815208116
Jansen, 2016, Bioengineered kidney tubules efficiently excrete uremic toxins, Sci Rep, 6, 26715, 10.1038/srep26715
Weber, 2016, Development of a microphysiological model of human kidney proximal tubule function, Kidney Int, 90, 627, 10.1016/j.kint.2016.06.011
Chapron, 2020, An improved vascularized, dual-channel microphysiological system facilitates modeling of proximal tubular solute secretion, ACS Pharmacol Transl Sci, 3, 496, 10.1021/acsptsci.9b00078
Bhargava, 2017, Mitochondrial energetics in the kidney, Nat Rev Nephrol, 13, 629, 10.1038/nrneph.2017.107
Vormann, 2018, Nephrotoxicity and kidney transport assessment on 3d perfused proximal tubules, AAPS J, 20, 90, 10.1208/s12248-018-0248-z
Vriend, 2018, Screening of drug-transporter interactions in a 3d microfluidic renal proximal tubule on a chip, AAPS J, 20, 87, 10.1208/s12248-018-0247-0
Vriend, 2020, Flow stimulates drug transport in a human kidney proximal tubule-on-a-chip independent of primary cilia, Biochim Biophys Acta Gen Subj, 1864, 129433, 10.1016/j.bbagen.2019.129433
Sakolish, 2018, Technology transfer of the microphysiological systems: a case study of the human proximal tubule tissue chip, Sci Rep, 8, 14882, 10.1038/s41598-018-33099-2
Sakolish, 2020, Predicting tubular reabsorption with a human kidney proximal tubule tissue-on-a-chip and physiologically-based modeling, Toxicol In Vitro, 63, 104752, 10.1016/j.tiv.2019.104752
van der Made, 2019, Quantitative translation of microfluidic transporter in vitro data to in vivo reveals impaired albumin-facilitated indoxyl sulfate secretion in chronic kidney disease, Mol Pharm, 16, 4551, 10.1021/acs.molpharmaceut.9b00681
Probst, 2018, High-throughput organ-on-a-chip systems: current status and remaining challenges, Curr Opin Biomed Eng, 6, 33, 10.1016/j.cobme.2018.02.004
Prasad, 2019, Toward a consensus on applying quantitative liquid chromatography-tandem mass spectrometry proteomics in translational pharmacology research: a white paper, Clin Pharmacol Ther, 106, 525, 10.1002/cpt.1537
Prasad, 2016, Abundance of drug transporters in the human kidney cortex as quantified by quantitative targeted proteomics, Drug Metab Dispos, 44, 1920, 10.1124/dmd.116.072066
Kumar, 2018, The importance of incorporating oct2 plasma membrane expression and membrane potential in ivive of metformin renal secretory clearance, Drug Metab Dispos, 46, 1441, 10.1124/dmd.118.082313
Scotcher, 2017, Microsomal and cytosolic scaling factors in dog and human kidney cortex and application for in vitro-in vivo extrapolation of renal metabolic clearance, Drug Metab Dispos, 45, 556, 10.1124/dmd.117.075242
Rodrigues, 2018, Endogenous probes for drug transporters: balancing vision with reality, Clin Pharmacol Ther, 103, 434, 10.1002/cpt.749
Chan, 2019, Bottom-up physiologically-based biokinetic modelling as an alternative to animal testing, ALTEX, 36, 597
Arafa, 2015, Tmigd1 is a novel adhesion molecule that protects epithelial cells from oxidative cell injury, Am J Pathol, 185, 2757, 10.1016/j.ajpath.2015.06.006
Alvarez, 2016, Comparative characterization of shiga toxin type 2 and subtilase cytotoxin effects on human renal epithelial and endothelial cells grown in monolayer and bilayer conditions, PloS One, 11, 10.1371/journal.pone.0158180
Wieser, 2008, Htert alone immortalizes epithelial cells of renal proximal tubules without changing their functional characteristics, Am J Physiol Ren Physiol, 295, F1365, 10.1152/ajprenal.90405.2008
