In vitro characterization of the immunotoxic potential of several perfluorinated compounds (PFCs)

Toxicology and Applied Pharmacology - Tập 258 Số 2 - Trang 248-255 - 2012
Emanuela Corsini1, Enrico Sangiovanni2, Anna Avogadro1, Valentina Galbiati1, Barbara Viviani1, Marina Marinovich1, C. Galli1, Mario Dell’Agli2, Dori R. Germolec3
1Laboratory of Toxicology, Department of Pharmacological Sciences, Università degli Studi di Milano, Via Balzaretti, 9, 20133 Milano, Italy
2Laboratory of Pharmacognosy, Department of Pharmacological Sciences, Università degli Studi di Milano, Via Balzaretti 9, 20133 Milano, Italy
3National Toxicology Program, National Institute of Environmental Health Sciences, NIH, RTP, NC, USA

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Tài liệu tham khảo

3M, 2006, Environmental, Health, Safety, and Regulatory (EHRS) profile of perfluorobutane sulfonate (PFBS)

Biegel, 2001, Mechanisms of extrahepatic tumor induction by peroxisome proliferators in male CD rats, Toxicol. Sci., 60, 44, 10.1093/toxsci/60.1.44

Brostjan, 1997, Glucocorticoids inhibit E-selectin expression by targeting NF-kappaB and not ATF/c-Jun, J. Immunol., 158, 3836, 10.4049/jimmunol.158.8.3836

Butenhoff, 2004, Characterization of risk for general population exposure to perfluorooctanoate, Regul. Toxicol. Pharmacol., 39, 363, 10.1016/j.yrtph.2004.03.003

Calafat, 2006, Human exposure assessment to environmental chemicals using biomonitoring, Int. J. Androl., 29, 166, 10.1111/j.1365-2605.2005.00570.x

Chinetti, 2000, Peroxisome proliferator-activated receptors (PPARs): nuclear receptors at the crossroads between lipid metabolism and inflammation, Inflamm. Res., 49, 497, 10.1007/s000110050622

Corsini, 2011, In vitro evaluation of the immunotoxic potential of perfluorinated compounds (PFCs), Toxicol. Appl. Pharmacol., 250, 108, 10.1016/j.taap.2010.11.004

Costa, 2009, Thirty years of medical surveillance in perfluooctanoic acid production workers, J Occup Environ Med, 51, 364, 10.1097/JOM.0b013e3181965d80

Crabtree, 1994, Signal transmission between the plasma membrane and nucleus of T lymphocytes, Annu. Rev. Biochem., 63, 1045, 10.1146/annurev.bi.63.070194.005145

DeWitt, 2009, Suppression of humoral immunity by perfluorooctanoic acid is independent of elevated serum corticosterone concentration in mice, Toxicol. Sci., 109, 106, 10.1093/toxsci/kfp040

DeWitt, 2008, Perfluorooctanoic acid-induced immunomodulation in adult C57BL/6J or C57BL/6N female mice, Environ. Health Perspect., 116, 644, 10.1289/ehp.10896

DeWitt, J.C., Peden-Adams, M.M., Keller, J.M. Germolec, D.R. 2011. The immunotoxicity of perfluorinated compounds: recent developments. Toxicol. Pathol. 2011 Nov 22 [Electronic publication ahead of print].

Emmett, 2006, Community exposure to perfluorooctanoate: relationships between serum levels and certain health parameters, J. Occup. Environ. Med., 48, 771, 10.1097/01.jom.0000233380.13087.37

Feng, 2009, Perfluorononanoic acid induces apoptosis involving the Fas death receptor signaling pathway in rat testis, Toxicol. Lett., 190, 224, 10.1016/j.toxlet.2009.07.020

Fromme, 2009, Perfluorinated compounds—exposure assessment for the general population in Western countries, Int. J. Hyg. Environ. Health, 212, 239, 10.1016/j.ijheh.2008.04.007

Guruge, 2009, Effect of perfluorooctane sulfonate (PFOS) on influenza A virus-induced mortality in female B6C3F1 mice, J. Toxicol. Sci., 34, 687, 10.2131/jts.34.687

Hagenaars, 2011, Structure–activity relationship assessment of four perfluorinated chemicals using a prolonged zebrafish early life stage test, Chemosphere, 82, 764, 10.1016/j.chemosphere.2010.10.076

Haug, 2011, Characterisation of human exposure pathways to perfluorinated compounds—comparing exposure estimates with biomarkers of exposure, Environ. Int., 37, 687, 10.1016/j.envint.2011.01.011

Hu, 2002, Inhibition of gap junctional intercellular communication by perfluorinated compounds in rat liver and dolphin kidney epithelial cell lines in vitro and Sprague–Dawley rats in vivo, Toxicol. Sci., 68, 429, 10.1093/toxsci/68.2.429

Ji, 2008, Toxicity of perfluorooctane sulfonic acid and perfluorooctanoic acid on freshwater macroinvertebrates (Daphnia magna and Moina macrocopa) and fish (Oryzias latipes), Environ. Toxicol. Chem., 27, 2159, 10.1897/07-523.1

Joensen, 2009, Do perfluoroalkyl compounds impair human semen quality?, Environ. Health Perspect., 117, 923, 10.1289/ehp.0800517

Kato, 2011, Trends in exposure to polyfluoroalkyl chemicals in the U.S. population: 1999–2008, Environ. Sci. Technol., 10.1021/es1043613

Kennedy, 2004, The toxicology of perfluorooctanoate, Crit. Rev. Toxicol., 34, 351, 10.1080/10408440490464705

Lau, 2004, The developmental toxicity of perfluoroalkyl acids and their derivatives, Toxicol. Appl. Pharmacol., 198, 231, 10.1016/j.taap.2003.11.031

Lieder, 2009, A two-generation oral gavage reproduction study with potassium perfluorobutanesulfonate (K+PFBS) in Sprague Dawley rats, Toxicology, 259, 33, 10.1016/j.tox.2009.01.027

Liu, 1996, The direct effect of hepatic peroxisome proliferators on rat Leydig cell function in vitro, Fundam. Appl. Toxicol., 30, 102, 10.1006/faat.1996.0047

Liu, 1996, Effect of the peroxisome proliferator, ammonium perfluorooctanoate (C8), on hepatic aromatase activity in adult male Crl:CDBR (CD) rats, Fundam. Appl. Toxicol., 30, 220, 10.1006/faat.1996.0059

Martin, 2003, Bioconcentration and tissue distribution of perfluorinated acids in rainbow trout (Oncorhynchus mykiss), Environ. Toxicol. Chem., 22, 196, 10.1002/etc.5620220126

Olsen, 1999, Serum perfluorooctane sulfonate and hepatic and lipid clinical chemistry tests in fluorochemical production employees, J. Occup. Environ. Med., 41, 799, 10.1097/00043764-199909000-00012

Olsen, 2007, Half-life of serum elimination of perfluorooctanesulfonate, perfluorohexanesulfonate, and perfluorooctanoate in retired fluorochemical production workers, Environ Health Perspect, 115, 1298, 10.1289/ehp.10009

Pastoor, 1987, Biochemical and morphological studies of ammonium perfluorooctanoate-induced hepatomegaly and peroxisome proliferation, Exp. Mol. Pathol., 47, 98, 10.1016/0014-4800(87)90011-6

Peden-Adams, 2007, Suppression of humoral immunity following exposure to the perfluorinated insecticide sulfluramid, J. Toxicol Environ. Health A., 70, 1130, 10.1080/15287390701252733

Peden-Adams, 2008, Suppression of humoral immunity in mice following exposure to perfluorooctane sulfonate, Toxicol. Sci., 104, 144, 10.1093/toxsci/kfn059

Qazi, 2009, Toxicology, 260, 68, 10.1016/j.tox.2009.03.009

Rayne, 2009, Perfluoroalkyl sulfonic and carboxylic acids: a critical review of physicochemical properties, levels and patterns in waters and wastewaters, and treatment methods, J. Environ. Sci. Health, Part A: Tox. Hazard. Subst. Environ. Eng., 44, 1145, 10.1080/10934520903139811

Saccani, 2002, p38-dependent marking of inflammatory genes for increased NF-kappa B recruitment, Nat. Immunol., 3, 69, 10.1038/ni748

Sambrook, 2001

Schmitz, 2001, I kappa B-independent control of NF-kappa B activity by modulatory phosphorylations, Trends Biochem. Sci., 26, 186, 10.1016/S0968-0004(00)01753-9

Steffens, 2004, Anti-inflammatory properties of statins, Semin. Vasc. Med., 4, 417, 10.1055/s-2004-869599

Steenland, 2010, Epidemiologic evidence on the health effects of perfluorooctanoic acid (PFOA), Environ. Health Perspect., 118, 1100, 10.1289/ehp.0901827

Suja, 2009, Contamination, bioaccumulation and toxic effects of perfluorinated chemicals (PFCs) in the water environment: a review paper, Water Sci. Technol., 60, 1533, 10.2166/wst.2009.504

Takacs, 2007, Activation of mouse and human peroxisome proliferator-activated receptors (alpha, beta/delta, gamma) by perfluorooctanoic acid and perfluorooctane sulfonate, Toxicol. Sci., 95, 108, 10.1093/toxsci/kfl135

Vermeulen, 2002, Regulation of the transcriptional activity of the nuclear factor-kappaB p65 subunit, Biochem. Pharmacol., 64, 963, 10.1016/S0006-2952(02)01161-9

Vermeulen, 2003, Transcriptional activation of the NF-kappaB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1), EMBO J., 22, 1313, 10.1093/emboj/cdg139

Viatour, 2005, Phosphorylation of NF-kappaB and IkappaB proteins: implications in cancer and inflammation, Trends Biochem. Sci., 30, 43, 10.1016/j.tibs.2004.11.009

Yang, 2002, Involvement of the peroxisome proliferator-activated receptor alpha in the immunomodulation caused by peroxisome proliferators in mice, Biochem. Pharmacol., 63, 1893, 10.1016/S0006-2952(02)00923-1

Yang, 2002, Potent suppression of the adaptive immune response in mice upon dietary exposure to the potent peroxisome proliferator, perfluorooctanoic acid, Int. Immunopharmacol., 2, 389, 10.1016/S1567-5769(01)00164-3

Yang, 2001, Further evidence for the involvement of inhibition of cell proliferation and development in thymic and splenic atrophy induced by the peroxisome proliferator perfluoroctanoic acid in mice, Biochem. Pharmacol., 62, 1133, 10.1016/S0006-2952(01)00752-3

Wang, 2011, The effect of prenatal perfluorinated chemicals exposures on pediatric atopy, Environ. Res., 10.1016/j.envres.2011.04.006