In silico Druggability Assessment of the NUDIX Hydrolase Protein Family as a Workflow for Target Prioritization

Maurice Michel1, Evert Homan1, Elisée Wiita1, Kia Pedersen1, Ingrid Almlöf1, Anna‐Lena Gustavsson2, Thomas Lundbäck2,3, Thomas Helleday4,1, Ulrika Warpman Berglund1
1Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Sweden
2Chemical Biology Consortium Sweden (CBCS), Science for Life Laboratory, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Sweden
3Mechanistic Biology and Profiling, Discovery Sciences, R&D, AstraZeneca, Sweden
4Department of Oncology and Metabolism, Sheffield Cancer Centre, University of Sheffield, United Kingdom

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