In Silico and In Vitro Analysis of IL36RN Alterations Reveals Critical Residues for the Function of the Interleukin-36 Receptor Complex

Journal of Investigative Dermatology - Tập 143 - Trang 2468-2475.e6 - 2023
Niina K. Hassi1, Timir Weston2, Giulia Rinaldi1, Joseph C. Ng2,3, Asma Smahi4, Sophie Twelves1, Camilla Davan-Wetton1, Dana Fakhreddine1, Franca Fraternali2,3, Francesca Capon1
1Department of Medical and Molecular Genetics, School of Basic and Medical Biosciences, King's College London, London, United Kingdom
2Randall Centre for Cell & Molecular Biophysics, School of Basic and Medical Biosciences, King’s College London, London, United Kingdom
3Institute of Structural and Molecular Biology, University College London, London, United Kingdom
4Imagine Institute, INSERM UMR 1163, Paris, France

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