Improved survival in amyotrophic lateral sclerosis patients following autologous bone marrow mononuclear cell therapy: a long term 10-year retrospective study
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Cleveland, 2001, From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS, Nat Rev Neurosci, 2, 806, 10.1038/35097565
Wijesekera, 2009, Amyotrophic lateral sclerosis, Orphanet J Rare Dis, 4, 1, 10.1186/1750-1172-4-3
Miller, 2012, Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND), Cochrane Database Syst Rev
Tanaka, 2016, A 24-week, phase III, double-blind, parallel-group study of edaravone (MCI-186) for treatment of amyotrophic lateral sclerosis (ALS), Neurology, 86, 189
Oskarsson, 2018, Amyotrophic lateral sclerosis: an update for 2018, Mayo Clin Proc, 93, 1617, 10.1016/j.mayocp.2018.04.007
Tanaka, 2016, A double-blind, parallel-group, placebo-controlled, 24-week, exploratory study of edaravone (MCI-186) for the treatment of advanced amyotrophic lateral sclerosis (ALS), Neurology, 86, 191
Abe, 2014, Confirmatory double-blind, parallel-group, placebo-controlled study of efficacy and safety of edaravone (MCI-186) in amyotrophic lateral sclerosis patients, Amyotroph Lateral Scler Frontotemporal Degener, 15, 610, 10.3109/21678421.2014.959024
Al-Chalabi, 2018, Finding a treatment for ALS - will gene editing cut it?, N Engl J Med, 378, 1454, 10.1056/NEJMcibr1716741
Moura, 2016, Efficacy of stem cell therapy in amyotrophic lateral sclerosis: a systematic review and meta-analysis, J Clin Med Res, 8, 317, 10.14740/jocmr2495w
Beers, 2011, Neuroinflammation modulates distinct regional and temporal clinical responses in ALS mice, Brain Behav Immun, 25, 1025, 10.1016/j.bbi.2010.12.008
Rizzo, 2014, Cellular therapy to target neuroinflammation in amyotrophic lateral sclerosis, Cell Mol Life Sci, 71, 999, 10.1007/s00018-013-1480-4
Blanquer, 2010, Bone marrow stem cell transplantation in amyotrophic lateral sclerosis: technical aspects and preliminary results from a clinical trial, Methods Find Exp Clin Pharmacol, 32, 31
Blanquer, 2012, Neurotrophic bone marrow cellular nests prevent spinal motoneuron degeneration in amyotrophic lateral sclerosis patients: a pilot safety study, Stem Cells, 30, 1277, 10.1002/stem.1080
Prabhakar, 2012, Autologous bone marrow-derived stem cells in amyotrophic lateral sclerosis: a pilot study, Neurol India, 60, 465, 10.4103/0028-3886.103185
Sharma, 2015, The effect of autologous bone marrow mononuclear cell transplantation on the survival duration in amyotrophic lateral sclerosis - a retrospective controlled study, Am J Stem Cells, 4, 50
General Assembly of the World Medical Association, 2014, World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects, J Am Coll Dent, 81, 14
Feldman, 2002, Age trends in the level of serum testosterone and other hormones in middle-aged men: longitudinal results from the Massachusetts male aging study, J Clin Endocrinol Metab, 87, 589, 10.1210/jcem.87.2.8201
Zmuda, 1997, Longitudinal relation between endogenous testosterone and cardiovascular disease risk factors in middle-aged men. A 13-year follow-up of former Multiple Risk Factor Intervention Trial participants, Am J Epidemiol, 146, 609, 10.1093/oxfordjournals.aje.a009326
Longinetti, 2019, Epidemiology of amyotrophic lateral sclerosis: an update of recent literature, Curr Opin Neurol, 32, 771, 10.1097/WCO.0000000000000730
Pupillo, 2014, Long-term survival in amyotrophic lateral sclerosis: a population-based study, Ann Neurol, 75, 287, 10.1002/ana.24096
Chio, 2009, Prognostic factors in ALS: A critical review, Amyotroph Lateral Scler, 10, 310, 10.3109/17482960802566824
Testa, 2004, Survival of 793 patients with amyotrophic lateral sclerosis diagnosed over a 28-year period, Amyotroph Lateral Scler Other Motor Neuron Disord, 5, 208, 10.1080/14660820410021311
del Aguila, 2003, Prognosis in amyotrophic lateral sclerosis: a population-based study, Neurology, 60, 813, 10.1212/01.WNL.0000049472.47709.3B
Tysnes, 1991, Epidemiology of amyotrophic lateral sclerosis in Hordaland County, western Norway, Acta Neurol Scand, 83, 280, 10.1111/j.1600-0404.1991.tb04701.x
Chiò, 2013, Global epidemiology of amyotrophic lateral sclerosis: a systematic review of the published literature, Neuroepidemiology, 41, 118, 10.1159/000351153
Manjaly, 2010, The sex ratio in amyotrophic lateral sclerosis: A population based study, Amyotroph Lateral Scler, 11, 439, 10.3109/17482961003610853
Gutiérrez-Lobos, 2002, The influence of age on the female/male ratio of treated incidence rates in depression, BMC Psychiatry, 2, 3, 10.1186/1471-244X-2-3
Sane, 2015, Autologous bone marrow mononuclear cell intrathecal transplantation may affect the survival duration in amyotrophic lateral sclerosis-Clinical study, 227
Nakamizo, 2000, Protection of cultured spinal motor neurons by estradiol, Neuroreport, 11, 3493, 10.1097/00001756-200011090-00019
Groeneveld, 2004, Ovariectomy and 17beta-estradiol modulate disease progression of a mouse model of ALS, Brain Res, 1021, 128, 10.1016/j.brainres.2004.06.024
Monachelli, 2011, Endogenous progesterone is associated to amyotrophic lateral sclerosis prognostic factors, Acta Neurol Scand, 123, 60, 10.1111/j.1600-0404.2010.01385.x
Gonzalez Deniselle, 2002, Progesterone neuroprotection in the Wobbler mouse, a genetic model of spinal cord motor neuron disease, Neurobiol Dis, 11, 457, 10.1006/nbdi.2002.0564
Gonzalez Deniselle, 2007, Progesterone modulates brain-derived neurotrophic factor and choline acetyltransferase in degenerating Wobbler motoneurons, Exp Neurol, 203, 406, 10.1016/j.expneurol.2006.08.019
Chió, 1991, Risk factors in motor neuron disease: a case-control study, Neuroepidemiology, 10, 174, 10.1159/000110267
Popat, 2006, Effect of reproductive factors and postmenopausal hormone use on the risk of amyotrophic lateral sclerosis, Neuroepidemiology, 27, 117, 10.1159/000095550
Gonzalez Deniselle, 2016, Steroid profiling in male wobbler mouse, a model of amyotrophic lateral sclerosis, Endocrinology, 157, 4446, 10.1210/en.2016-1244
McLeod, 2019, Androgen receptor antagonism accelerates disease onset in the SOD1G93A mouse model of amyotrophic lateral sclerosis, Br J Pharmacol, 176, 2111, 10.1111/bph.14657
Sane H, Paranjape A, Nivins S. Correlation of testosterone levels with progression of amyotrophic lateral sclerosis: a cross section study. 2017.
Rosen, 1993, Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis, Nature, 362, 59, 10.1038/362059a0
Boillée, 2006, ALS: a disease of motor neurons and their nonneuronal neighbors, Neuron, 52, 39, 10.1016/j.neuron.2006.09.018
Appel, 2010, T cell-microglial dialogue in Parkinson's disease and amyotrophic lateral sclerosis: are we listening?, Trends Immunol, 31, 7, 10.1016/j.it.2009.09.003
Zhao, 2004, Activated microglia initiate motor neuron injury by a nitric oxide and glutamate-mediated mechanism, J Neuropathol Exp Neurol, 63, 964, 10.1093/jnen/63.9.964
Burguillos, 2011, Caspase signalling controls microglia activation and neurotoxicity, Nature, 472, 319, 10.1038/nature09788
Ghoshal, 2007, Proinflammatory mediators released by activated microglia induces neuronal death in Japanese encephalitis, Glia, 55, 483, 10.1002/glia.20474
Zhao, 2013, Immune-mediated mechanisms in the pathoprogression of amyotrophic lateral sclerosis, J Neuroimmune Pharmacol, 8, 888, 10.1007/s11481-013-9489-x
Neher, 2011, Inhibition of microglial phagocytosis is sufficient to prevent inflammatory neuronal death, J Immunol, 186, 4973, 10.4049/jimmunol.1003600
Norden, 2013, Review: microglia of the aged brain: primed to be activated and resistant to regulation, Neuropathol Appl Neurobiol, 39, 19, 10.1111/j.1365-2990.2012.01306.x
Hu, 2015, Microglial and macrophage polarization—new prospects for brain repair, Nat Rev Neurol, 11, 56, 10.1038/nrneurol.2014.207
Dupuis, 2012, A randomized, double blind, placebo-controlled trial of pioglitazone in combination with riluzole in amyotrophic lateral sclerosis, PLoS One, 7, 10.1371/journal.pone.0037885
Smith, 1994, Treatment of ALS with high dose pulse cyclophosphamide, J Neurol Sci, 124, 84, 10.1016/0022-510X(94)90188-0
Brown, 1986, Failure of immunosuppression with a 10- to 14-day course of high-dose intravenous cyclophosphamide to alter the progression of amyotrophic lateral sclerosis, Arch Neurol, 43, 383, 10.1001/archneur.1986.00520040063021
Cudkowicz, 2006, Trial of celecoxib in amyotrophic lateral sclerosis, Ann Neurol, 60, 22, 10.1002/ana.20903
Stommel, 2009, Efficacy of thalidomide for the treatment of amyotrophic lateral sclerosis: a phase II open label clinical trial, Amyotroph Lateral Scler, 10, 393, 10.3109/17482960802709416
Gordon, 2007, Efficacy of minocycline in patients with amyotrophic lateral sclerosis: a phase III randomised trial, Lancet Neurol, 6, 1045, 10.1016/S1474-4422(07)70270-3
Levine, 2012, A pilot trial of pioglitazone HCl and tretinoin in ALS: cerebrospinal fluid biomarkers to monitor drug efficacy and predict rate of disease progression, Neurol Res Int, 2012, 10.1155/2012/582075
Xie, 2016, Bone marrow-derived cells: from the laboratory to the clinic, 27
Challen, 2006, A side order of stem cells: the SP phenotype, Stem Cells, 24, 3, 10.1634/stemcells.2005-0116
Salem, 2010, Mesenchymal stromal cells: current understanding and clinical status, Stem Cells, 28, 585, 10.1002/stem.269
Kucia, 2008, Evidence that very small embryonic-like stem cells are mobilized into peripheral blood, Stem Cells, 26, 2083, 10.1634/stemcells.2007-0922
Ji, 2008, Simultaneous expression of Oct4 and genes of three germ layers in single cell-derived multipotent adult progenitor cells, Ann Hematol, 87, 431, 10.1007/s00277-008-0470-3
Park, 2005, Evidence for the hemangioblast, Exp Hematol, 33, 965, 10.1016/j.exphem.2005.06.003
Kucia, 2005, Bone marrow as a home of heterogenous populations of nonhematopoietic stem cells, Leukemia, 19, 1118, 10.1038/sj.leu.2403796
Yang, 2016, Various cell populations within the mononuclear fraction of bone marrow contribute to the beneficial effects of autologous bone marrow cell therapy in a rodent stroke model, Transl Stroke Res, 7, 322, 10.1007/s12975-016-0462-x
Kim, 2009, Mesenchymal stem cell-educated macrophages: a novel type of alternatively activated macrophages, Exp Hematol, 37, 1445, 10.1016/j.exphem.2009.09.004
Hegyi, 2014, Regulation of mouse microglia activation and effector functions by bone marrow-derived mesenchymal stem cells, Stem Cells Dev, 23, 2600, 10.1089/scd.2014.0088
Liu, 2013, Interplay between human microglia and neural stem/progenitor cells in an allogeneic co-culture model, J Cell Mol Med, 17, 1434, 10.1111/jcmm.12123
Yan, 2013, Bone marrow-derived mesenchymal stem cells maintain the resting phenotype of microglia and inhibit microglial activation, PLoS One, 8, 10.1371/journal.pone.0084116
Pastor, 2012, Comparative effects between bone marrow and mesenchymal stem cell transplantation in GDNF expression and motor function recovery in a motorneuron degenerative mouse model, Stem Cell Rev Rep, 8, 445, 10.1007/s12015-011-9295-x
Labouyrie, 1999, Expression of neurotrophins and their receptors in human bone marrow, Am J Pathol, 154, 405, 10.1016/S0002-9440(10)65287-X
Jones, 2010, Mesenchymal stem cells rescue Purkinje cells and improve motor functions in a mouse model of cerebellar Ataxia, Neurobiol Dis, 40, 415, 10.1016/j.nbd.2010.07.001
Auffray, 1996, Nerve growth factor is involved in the supportive effect by bone marrow-derived stromal cells of the factor-dependent human cell line UT-7, Blood, 88, 1608, 10.1182/blood.V88.5.1608.1608
Wang, 2007, Vascular endothelial growth factor overexpression delays neurodegeneration and prolongs survival in amyotrophic lateral sclerosis mice, J Neurosci, 27, 304, 10.1523/JNEUROSCI.4433-06.2007
Cabanes, 2007, Neuroprotective effect of adult hematopoietic stem cells in a mouse model of motoneuron degeneration, Neurobiol Dis, 26, 408, 10.1016/j.nbd.2007.01.008
Suzuki, 2007, GDNF secreting human neural progenitor cells protect dying motor neurons, but not their projection to muscle, in a rat model of familial ALS, PLoS One, 2, e689, 10.1371/journal.pone.0000689
Wang, 2014, Bone marrow mononuclear cell transplantation promotes therapeutic angiogenesis via upregulation of the VEGF-VEGFR2 signaling pathway in a rat model of vascular dementia, Behav Brain Res, 265, 171, 10.1016/j.bbr.2014.02.033
Oosthuyse, 2001, Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration, Nat Genet, 28, 131, 10.1038/88842
Jin, 2000, Vascular endothelial growth factor: direct neuroprotective effect in in vitro ischemia, Proc Natl Acad Sci USA, 97, 10242, 10.1073/pnas.97.18.10242
Jin, 2000, Induction of vascular endothelial growth factor receptors and phosphatidylinositol 3’-kinase/Akt signaling by global cerebral ischemia in the rat, Neuroscience, 100, 713, 10.1016/S0306-4522(00)00331-6
Silverman, 1999, Vascular, glial and neuronal effects of vascular endothelial growth factor in mesencephalic explant cultures, Neuroscience, 90, 1529, 10.1016/S0306-4522(98)00540-5
Carmeliet, 2013, VEGF ligands and receptors: implications in neurodevelopment and neurodegeneration, Cell Mol Life Sci, 70, 1763, 10.1007/s00018-013-1283-7
Ruiz de Almodovar, 2009, Role and therapeutic potential of VEGF in the nervous system, Physiol Rev, 89, 607, 10.1152/physrev.00031.2008
Azzouz, 2004, VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model, Nature, 429, 413, 10.1038/nature02544
Storkebaum, 2005, Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS, Nat Neurosci, 8, 85, 10.1038/nn1360
Zheng, 2004, Vascular endothelial growth factor prolongs survival in a transgenic mouse model of ALS, Ann Neurol, 56, 564, 10.1002/ana.20223
Feng, 2008, Combined lithium and valproate treatment delays disease onset, reduces neurological deficits and prolongs survival in an amyotrophic lateral sclerosis mouse model, Neuroscience, 155, 567, 10.1016/j.neuroscience.2008.06.040
Chen, 1999, Long term lithium treatment suppresses p53 and Bax expression but increases Bcl-2 expression. A prominent role in neuroprotection against excitotoxicity, J Biol Chem, 274, 6039, 10.1074/jbc.274.10.6039
Shalbuyeva, 2007, Lithium desensitizes brain mitochondria to calcium, antagonizes permeability transition, and diminishes cytochrome C release, J Biol Chem, 282, 18057, 10.1074/jbc.M702134200
Bachmann, 2009, Common effects of lithium and valproate on mitochondrial functions: protection against methamphetamine-induced mitochondrial damage, Int J Neuropsychopharmacol, 12, 805, 10.1017/S1461145708009802
Quiroz, 2010, Novel insights into lithium's mechanism of action: neurotrophic and neuroprotective effects, Neuropsychobiology, 62, 50, 10.1159/000314310
Bosche, 2013, Lithium prevents early cytosolic calcium increase and secondary injurious calcium overload in glycolytically inhibited endothelial cells, Biochem Biophys Res Commun, 434, 268, 10.1016/j.bbrc.2013.03.047
Ngok-Ngam, 2013, Pharmacological inhibition of GSK3 attenuates DNA damage-induced apoptosis via reduction of p53 mitochondrial translocation and Bax oligomerization in neuroblastoma SH-SY5Y cells, Cell Mol Biol Lett, 18, 58, 10.2478/s11658-012-0039-y
Feier, 2013, Lithium and valproate modulate energy metabolism in an animal model of mania induced by methamphetamine, Pharmacol Biochem Behav, 103, 589, 10.1016/j.pbb.2012.09.010
Busceti, 2008, Enhanced tau phosphorylation in the hippocampus of mice treated with 3,4-methylenedioxymethamphetamine (“Ecstasy”), J Neurosci, 28, 3234, 10.1523/JNEUROSCI.0159-08.2008
Fornai, 2008, Lithium delays progression of amyotrophic lateral sclerosis, Proc Natl Acad Sci USA, 105, 2052, 10.1073/pnas.0708022105
Harris, 2012, Clinical and pathological effects of intrathecal injection of mesenchymal stem cell-derived neural progenitors in an experimental model of multiple sclerosis, J Neurol Sci, 313, 167, 10.1016/j.jns.2011.08.036
Wu, 2002, New method for transplantation of neurosphere cells into injured spinal cord through cerebrospinal fluid in rat, Neurosci Lett, 318, 81, 10.1016/S0304-3940(01)02488-0
Bai, 2003, Dissemination and proliferation of neural stem cells on the spinal cord by injection into the fourth ventricle of the rat: a method for cell transplantation, J Neurosci Methods, 124, 181, 10.1016/S0165-0270(03)00007-4
Fischer, 2009, Pulmonary passage is a major obstacle for intravenous stem cell delivery: the pulmonary first-pass effect, Stem Cells Dev, 18, 683, 10.1089/scd.2008.0253
Vasconcelos-dos-Santos, 2012, Intravenous and intra-arterial administration of bone marrow mononuclear cells after focal cerebral ischemia: Is there a difference in biodistribution and efficacy?, Stem Cell Res, 9, 1, 10.1016/j.scr.2012.02.002
Sadan, 2009, Bone-marrow-derived mesenchymal stem cell therapy for neurodegenerative diseases, Expert Opin Biol Ther, 9, 1487, 10.1517/14712590903321439
Pastor, 2013, Bone marrow transplantation in hindlimb muscles of motoneuron degenerative mice reduces neuronal death and improves motor function, Stem Cells Dev, 22, 1633, 10.1089/scd.2012.0487
Corti, 2004, Wild-type bone marrow cells ameliorate the phenotype of SOD1-G93A ALS mice and contribute to CNS, heart and skeletal muscle tissues, Brain, 127, 2518, 10.1093/brain/awh273
Gubert, 2019, Bone-marrow mononuclear cell therapy in a mouse model of amyotrophic lateral sclerosis: Functional outcomes from different administration routes, Brain Res, 1712, 73, 10.1016/j.brainres.2019.02.003
Gubert, 2016, Intraspinal bone-marrow cell therapy at pre- and symptomatic phases in a mouse model of amyotrophic lateral sclerosis, Stem Cell Res Ther, 7, 41, 10.1186/s13287-016-0293-4
R. Martinez, 2017, Intrathecal delivery of bone marrow stem cells in ALS: A preliminary report, Trends in Transplant, 10, 1, 10.15761/TiT.1000220
Deda, 2009, Treatment of amyotrophic lateral sclerosis patients by autologous bone marrow-derived hematopoietic stem cell transplantation: a 1-year follow-up, Cytotherapy, 11, 18, 10.1080/14653240802549470
Ruiz-López, 2016, Breathing pattern in a phase I clinical trial of intraspinal injection of autologous bone marrow mononuclear cells in patients with amyotrophic lateral sclerosis, Respir Physiol Neurobiol, 221, 54, 10.1016/j.resp.2015.11.007