Impact of preformed and de novo anti-HLA DP antibodies in renal allograft survival

Pei, 2003, Single human leukocyte antigen flow cytometry beads for accurate identification of human leukocyte antigen antibody specificities, Transplantation, 75, 43, 10.1097/00007890-200301150-00008 Mizutani, 2007, The importance of anti-HLA-specific antibody strength in monitoring kidney transplant patients, Am. J. Transplant., 7, 1027, 10.1111/j.1600-6143.2006.01721.x Tait, 2013, Consensus guidelines on the testing and clinical management issues associated with HLA and non-HLA antibodies in transplantation, Transplantation, 95, 19, 10.1097/TP.0b013e31827a19cc Lefaucheur, 2010, Preexisting donor-specific HLA antibodies predict outcome in kidney transplantation, J. Am. Soc. Nephrol., 21, 1398, 10.1681/ASN.2009101065 Gloor, 2010, Baseline donor-specific antibody levels and outcomes in positive crossmatch kidney transplantation, Am. J. Transplant., 10, 582, 10.1111/j.1600-6143.2009.02985.x Wiebe, 2012, Evolution and clinical–pathologic correlations of de novo donor-specific HLA antibody post kidney transplant, Am. J. Transplant., 12, 1157, 10.1111/j.1600-6143.2012.04013.x Loupy, 2012, The impact of donor-specific anti-HLA antibodies on late kidney allograft failure, Nat. Rev. Nephrol., 8, 348, 10.1038/nrneph.2012.81 Everly, 2013, Incidence and impact of de novo donor-specific alloantibody in primary renal allografts, Transplantation, 91, 410, 10.1097/TP.0b013e31827d62e3 Gilbert, 2011, Impact of pretransplant human leukocyte antigen-C and -DP antibodies on kidney graft outcome, Transplant. Proc., 43, 3412, 10.1016/j.transproceed.2011.09.023 Versluis, 1993, High-resolution HLA-DPB typing based upon computerized analysis of data obtained by fluorescent sequencing of the amplified polymorphic exon 2, Hum. Immunol., 38, 277, 10.1016/0198-8859(93)90555-F Billen, 2010, HLA-DP antibodies before and after renal transplantation, Tissue Antigens, 75, 278, 10.1111/j.1399-0039.2009.01428.x Pfeiffer, 1995, HLA-DP antibodies in patients awaiting renal transplantation, Transpl. Int., 8, 180, 10.1111/j.1432-2277.1995.tb01500.x Youngs, 2004, HLA-DP alloantibodies, 60 Ling, 2012, Pretransplant anti-HLA-Cw and anti-HLA-DP antibodies in sensitized patients, Hum. Immunol., 73, 879, 10.1016/j.humimm.2012.07.320 Mytilineos, 1997, Clinical relevance of HLA-DPB locus matching for cadaver kidney retransplants: a report of the Collaborative Transplant Study, Transplantation, 63, 1351, 10.1097/00007890-199705150-00025 Qiu, 2005, Detection of antibodies to HLA-DP in renal transplant recipients using single antigen beads, Transplantation, 80, 1511, 10.1097/01.tp.0000181384.49832.3a Caro-Oleas, 2012, Clinical relevance of anti-HLA donor-specific antibodies detected by Luminex assay in the development of rejection after renal transplantation, Transplantation, 94, 338, 10.1097/TP.0b013e31825ace2c Lachmann, 2009, Anti-human leukocyte antigen and donor-specific antibodies detected by Luminex posttransplant serve as biomarkers for chronic rejection of renal allografts, Transplantation, 87, 1505, 10.1097/TP.0b013e3181a44206 Crespo, 2013, Clinical relevance of pretransplant anti-HLA donor-specific antibodies: does C1q-fixation matter?, Transpl. Immunol., 29, 28, 10.1016/j.trim.2013.07.002 Loupy, 2013, Complement-binding anti-HLA antibodies and kidney-allograft survival, N. Engl. J. Med., 369, 1215, 10.1056/NEJMoa1302506 DeVos, 2012, Donor-specific HLA-DQ antibodies may contribute to poor graft outcome after renal transplantation, Kidney Int., 82, 598, 10.1038/ki.2012.190 Willicombe, 2012, De novo DQ donor specific antibodies are associated with a significant risk of antibody-mediated rejection and transplant glomerulopathy, Transplantation, 94, 172, 10.1097/TP.0b013e3182543950 Wiebe, 2013, Class II HLA epitope matching—a strategy to minimize de novo donor specific antibody development and improve outcomes, Am. J. Transplant., 13, 3114, 10.1111/ajt.12478 Jolly, 2012, Preformed donor HLA-DP-specific antibodies mediate acute and chronic antibody-mediated rejection following renal transplantation, Am. J. Transplant., 12, 2845, 10.1111/j.1600-6143.2012.04172.x Bachelet, 2015, Deleterious impact of donor-specific anti-HLA antibodies toward HLA-Cw and HLA-DP in kidney transplantation, Transplantation Goral, 2008, Preformed donor-directed anti-HLA-DP antibodies may be an impediment to successful kidney transplantation, Nephrol. Dial. Transplant., 23, 390, 10.1093/ndt/gfm703 Thaunat, 2009, Chronic humoral rejection mediated by anti-HLA-DP alloantibodies: insights into the role of epitope sharing in donor-specific and non-donor specific alloantibodies generation, Transpl. Immunol., 20, 209, 10.1016/j.trim.2008.12.006 Singh, 2010, Acute humoral rejection in a zero mismatch deceased donor renal transplant due to an antibody to an HLA-DP alpha, Transplantation, 90, 220, 10.1097/TP.0b013e3181e1177d