Immunological characterization of the complement regulator factor H-binding CRASP and Erp proteins of Borrelia burgdorferi

Akins, 1999, Molecular and evolutionary analysis of Borrelia burgdorferi 297 circular plasmid-encoded lipoproteins with OspE- and OspF-like leader peptides, Infect. Immun., 67, 1526, 10.1128/IAI.67.3.1526-1532.1999 Alitalo, 2001, Complement evasion by Borrelia burgdorferi: serum-resistant strains promote C3b inactivation, Infect. Immun., 69, 3685, 10.1128/IAI.69.6.3685-3691.2001 Alitalo, 2002, Complement inhibitor factor H binding to Lyme disease spirochetes is mediated by inducible expression of multiple plasmid-encoded outer surface protein E paralogs, J. Immunol., 169, 3847, 10.4049/jimmunol.169.7.3847 Breitner-Ruddock, 1997, Heterogeneity in the complement-dependent bacteriolysis within the species of Borrelia burgdorferi, Med. Microbiol. Immunol., 185, 253, 10.1007/s004300050038 Casjens, 1997, Homology throughout the multiple 32-kilobase circular plasmids present in Lyme disease spirochete, J. Bacteriol., 179, 217, 10.1128/jb.179.1.217-227.1997 El-Hage, 2001, Surface exposure and protease insensitivity of Borrelia burgdorferi Erp (OspE/F-related) lipoproteins, Microbiology, 147, 821, 10.1099/00221287-147-4-821 Hellwage, 2001, The complement regulator factor H binds to the surface protein OspE of Borrelia burgdorferi, J. Biol. Chem., 276, 8427, 10.1074/jbc.M007994200 Kraiczy, 2000, Comparison of two laboratory methods for the determination of serum resistance in Borrelia burgdorferi isolates, Immunobiology, 201, 406, 10.1016/S0171-2985(00)80094-7 Kraiczy, 2001, Immune evasion of Borrelia burgdorferi by acquisition of human complement regulators FHL-1 and factor H, Eur. J. Immunol., 31, 1674, 10.1002/1521-4141(200106)31:6<1674::AID-IMMU1674>3.0.CO;2-2 Kraiczy, 2001, Further characterization of complement regulator-acquiring surface proteins of Borrelia burgdorferi, Infect. Immun., 69, 7800, 10.1128/IAI.69.12.7800-7809.2001 Kraiczy, 2002, Complement regulator-acquiring surface proteins of Borrelia burgdorferi: A new protein family involved in complement resistance, Wien. Klin. Wochenschr., 114, 568 Kraiczy, 2003, Immune evasion of Borrelia burgdorferi: mapping of a complement inhibitor factor H-binding site of BbCRASP-3, a novel member of the Erp protein family, Eur. J. Immunol., 33, 697, 10.1002/eji.200323571 Kühn, 1995, Mapping of the complement regulatory domains in the human factor H-like protein 1 and in factor H, J. Immunol., 155, 5663, 10.4049/jimmunol.155.12.5663 Kurtenbach, 1998, Serum complement sensitivity as a key factor in Lyme disease ecology, Infect. Immun., 66, 1248, 10.1128/IAI.66.3.1248-1251.1998 Kurtenbach, 2002, Host association of Borrelia burgdorferi- the key role of host complement, Trends Microbiol., 10, 74, 10.1016/S0966-842X(01)02298-3 Lindahl, 2000, Human complement regulators: a major target for pathogenic microorganisms, Curr. Opin. Immunol., 12, 44, 10.1016/S0952-7915(99)00049-7 Mbow, 2002, Borrelia burgdorferi-specific monoclonal antibodies derived from mice primed with Lyme disease spirochete-infected Ixodes scapularis ticks, Hybridoma, 21, 179, 10.1089/153685902760173890 Pangburn, 1997, Human complement C3b inactivator: isolation, characterization, and demonstration of an absolute requirement for the serum protein β1H for cleavage of C3b and C4b in solution, J. Exp. Med., 146, 257, 10.1084/jem.146.1.257 Prodinger, 1998, The C-terminus of factor H: monoclonal antibodies inhibit heparin binding and identify epitopes common to factor H and factor H-related proteins, Biochem. J., 31, 41, 10.1042/bj3310041 Stevenson, 1996, A family of genes located on four separate 32-kilobase circular plasmids in Borrelia burgdorferi B31, J. Bacteriol., 178, 3508, 10.1128/jb.178.12.3508-3516.1996 Stevenson, 1998, Borrelia burgdorferi Erp proteins are immunogenic in mammals infected by tick bite, and their synthesis is inducible in cultured bacteria, Infect. Immun., 66, 2648, 10.1128/IAI.66.6.2648-2654.1998 Stevenson, 1998, Evidence of past recombination events among the genes encoding the Erp antigens of Borrelia burgdorferi, Microbiology, 144, 1869, 10.1099/00221287-144-7-1869 Stevenson, 2000, Repetition, conservation, and variation: the multiple cp32 plasmids of Borrelia species, J. Mol. Microbiol. Biotechnol., 2, 411 Stevenson, 2002, Differential binding to host complement inhibitor factor H by Borrelia burgdorferi Erp surface proteins: a possible mechanism underlying the expansive host range of Lyme disease spirochete, Infect. Immun., 70, 491, 10.1128/IAI.70.2.491-497.2002 Van Dam, 1997, Complement-mediated serum sensitivity among spirochetes that cause Lyme disease, Infect. Immun., 65, 1228, 10.1128/IAI.65.4.1228-1236.1997 Walport, 2001, Complement. First of two parts, N. Engl. J. Med., 344, 1058, 10.1056/NEJM200104053441406 Whaley, 1976, Modulation of the alternative complement pathways by beta 1 H globulin, J. Exp. Med., 144, 1147, 10.1084/jem.144.5.1147 Würzner, 1999, Evasion of pathogens by avoiding recognition or eradication by complement, in part via molecular mimicry, Mol. Immunol., 36, 249, 10.1016/S0161-5890(99)00049-8 Zipfel, 1999, FHL-1: a human complement and immune regulator with cell-adhesive function, Immunol. Today, 20, 135, 10.1016/S0167-5699(98)01432-7