Immunohistochemical analyses of paraffin-embedded sections after primary surgery or trimodality treatment in esophageal carcinoma

Clinical and Translational Radiation Oncology - Tập 36 - Trang 106-112 - 2022
Benjamin Terfa Igbo1,2, Annett Linge2,3,4,5, Susanne Frosch3,5, Theresa Suckert2,4, Liane Stolz-Kieslich4, Steffen Löck1,6,3, Mani Sankari Kumaravadivel7,4, Thilo Welsch8, Jürgen Weitz8,5, Ulrich Sommer9, Daniela Aust9,10, Esther G.C. Troost1,2,3,4,5
1Institute of Radiooncology - OncoRay, Helmholtz-Zentrum Dresden-Rossendorf, Rossendorf, Germany
2OncoRay – National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Helmholtz-Zentrum Dresden – Rossendorf, Dresden, Germany
3Department of Radiotherapy and Radiation Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
4German Cancer Consortium (DKTK), partner site Dresden, and German Cancer Research Center (DKFZ), Heidelberg, Germany
5National Center for Tumor Diseases (NCT), Partner Site Dresden, Germany: German Cancer Research Center (DKFZ), Heidelberg, Germany; Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany, and; Helmholtz Association / Helmholtz-Zentrum Dresden - Rossendorf (HZDR), Dresden, Germany
6OncoRay – National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Helmholtz-Zentrum Dresden - Rossendorf, Dresden, Germany
7OncoRay – National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany
8Department of Visceral, Thoracic and Vascular Surgery (VTG), Faculty of Medicine and University Hospital Carl Gustav Carus, Dresden, Germany
9Institute of Pathology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Germany
10Institute for Pathology and Tumor and Normal Tissue Bank of the University Cancer Center (UCC), University Hospital Carl Gustav Carus, Medical Faculty, Technische Universität Dresden, Dresden, Germany

Tài liệu tham khảo

Shapiro, 2015, Neoadjuvant chemoradiotherapy plus surgery versus surgery alone for oesophageal or junctional cancer (CROSS): Long-term results of a randomised controlled trial, Lancet Oncol, 10.1016/S1470-2045(15)00040-6 van Hagen, 2012, Preoperative Chemoradiotherapy for Esophageal or Junctional Cancer, N Engl J Med, 366, 2074, 10.1056/NEJMoa1112088 de Gouw, 2019, Detecting Pathological Complete Response in Esophageal Cancer after Neoadjuvant Therapy Based on Imaging Techniques: A Diagnostic Systematic Review and Meta-Analysis, Journal of Thoracic Oncology, 10.1016/j.jtho.2019.04.004 Weber, 2020 Basu, 2019, Overview of Important “Organs at Risk” (OAR) in Modern Radiotherapy for Head and Neck Cancer (HNC), In: Cancer Survivorship Apolle, 2017, The clinical target volume in lung, head-and-neck, and esophageal cancer: Lessons from pathological measurement and recurrence analysis. Clinical and Translational, Radiation Oncology Van Der Heijden, 2019, Acute hypoxia profile is a stronger prognostic factor than chronic hypoxia in advanced stage head and neck cancer patients, Cancers (Basel), 11, 10.3390/cancers11040583 Helbig L, Koi L, Brüchner K, Gurtner K, Hess-Stumpp H, Unterschemmann K, et al. Hypoxia-inducible factor pathway inhibition resolves tumor hypoxia and improves local tumor control after single-dose irradiation. Int J Radiat Oncol Biol Phys [Internet]. 2014;88(1):159–66. Available from: http://dx.doi.org/10.1016/j.ijrobp.2013.09.047. Bussink, 1998, Multiparameter analysis of vasculature, perfusion and proliferation in human tumour xenografts, Br J Cancer, 10.1038/bjc.1998.9 Apolle, 2019, Inter-observer variability in target delineation increases during adaptive treatment of head-and-neck and lung cancer, Acta Oncol (Madr), 10.1080/0284186X.2019.1629017 Rice, 2017, 8th edition AJCC/UICC staging of cancers of the esophagus and esophagogastric junction: Application to clinical practice, Ann Cardiothorac Surg, 6, 119, 10.21037/acs.2017.03.14 Van Heijl, 2008, Neoadjuvant chemoradiation followed by surgery versus surgery alone for patients with adenocarcinoma or squamous cell carcinoma of the esophagus (CROSS), BMC Surg, 8, 1, 10.1186/1471-2482-8-21 Tumor- und Normalgewebebank des Nationalen Centrum für Tumorerkrankungen Dresden (NCT/UCC)-(TNTB) [Internet]. Available from: https://www.uniklinikum-dresden.de/de/das-klinikum/universitaetscentren/universitaets-krebscentrum-ucc/core-units/tumor-und-normalgewebebank (Accessed 17.02.2022). Bankhead, 2017, QuPath: Open source software for digital pathology image analysis, Sci Rep, 10.1038/s41598-017-17204-5 Schmidt, 2018, Cell detection with star-convex polygons Koishi, 2006, Persistent CXCR4 expression after preoperative chemoradiotherapy predicts early recurrence and poor prognosis in esophageal cancer, World J Gastroenterol, 10.3748/wjg.v12.i47.7585 Göbel, 2022, PD-1 and PD-L1 expression predict regression and prognosis following neoadjuvant radiochemotherapy of oesophageal adenocarcinoma, Clin Transl Radiat Oncol, 34, 90, 10.1016/j.ctro.2022.04.001 Chen, 2016, Prognostic significance of programmed death-1 and programmed death-ligand 1 expression in patients with esophageal squamous cell carcinoma, Oncotarget, 7, 30772, 10.18632/oncotarget.8956 Yamamoto, 2020, Tumor-infiltrating M2 macrophage in pretreatment biopsy sample predicts response to chemotherapy and survival in esophageal cancer, Cancer Sci, 10.1111/cas.14328 Kießler, 2021, Tumor-infiltrating plasmacytoid dendritic cells are associated with survival in human colon cancer, J Immunother Cancer, 9, 1, 10.1136/jitc-2020-001813 Ogawa, 2011, Clinical significance of HIF-1α expression in patients with esophageal cancer treated with concurrent chemoradiotherapy, Anticancer Res Linge, 2016, Low cancer stem cell marker expression and low hypoxia identify good prognosis subgroups in HPV(-) HNSCC after postoperative radiochemotherapy: A multicenter study of the DKTK-ROG, Clin Cancer Res, 10.1158/1078-0432.CCR-15-1990 Huang, 2020, The Impacts of Different Types of Radiation on the CRT and PDL1 Expression in Tumor Cells Under Normoxia and Hypoxia, Front Oncol, 10, 1 Chen, 2020, HIF1A expression correlates with increased tumor immune and stromal signatures and aggressive phenotypes in human cancers, Cell Oncol, 10.1007/s13402-020-00534-4 Roma-Rodrigues, 2019, Targeting tumor microenvironment for cancer therapy, Int J Mol Sci, 10.3390/ijms20040840 Vaupel, 2004, The Role of Hypoxia-Induced Factors in Tumor Progression, Oncologist, 10.1634/theoncologist.9-90005-10 Graeber, 1996, Potential in Solid Tumours, 379, 88 López de Andrés, 2020, Cancer stem cell secretome in the tumor microenvironment: a key point for an effective personalized cancer treatment, Journal of Hematology and Oncology, 10.1186/s13045-020-00966-3 Liu, 2020, Radiotherapy targeting cancer stem cells “awakens” them to induce tumour relapse and metastasis in oral cancer. International, J Oral Sci, 10.1038/s41368-020-00087-0 Huijskens, 2021, Radical radiotherapy for paediatric solid tumour metastases: An overview of current European protocols and outcomes of a SIOPE multicenter survey, Eur J Cancer, 10.1016/j.ejca.2020.12.004