Immunoadsorption therapy for dilated cardiomyopathy and pulmonary arterial hypertension

Atherosclerosis Supplements - Tập 14 - Trang 203-211 - 2013
Michael Dandel1, Gerd Wallukat2, Angela Englert1, Roland Hetzer1
1Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
2Max-Delbrück Center, Berlin, Germany

Tài liệu tham khảo

Maron, 2006, Contemporary definitions and classification of cardiomyopathies: an American Heart Association Scientific Statement, Circulation, 113, 1807, 10.1161/CIRCULATIONAHA.106.174287 Lappé, 2008, Recent insights into the role of autoimmunity in idiopathic dilated cardiomyopathy, J Card Fail, 14, 521, 10.1016/j.cardfail.2008.02.016 Anderson, 1982, Deficient natural killer cell activity in patients with idiopathic dilated cardiomyopathy, Lancet, 2, 1124, 10.1016/S0140-6736(82)92786-6 Limas, 1995, Soluble interleukin-2 receptor levels in patients with dilated cardiomyopathy: correlation with disease severity and cardiac antibodies, Circulation, 91, 631, 10.1161/01.CIR.91.3.631 Gerli, 1986, Immunologic studies of peripheral blood from patients with idiopathic dilated cardiomyopathy, Am Heart J, 112, 350, 10.1016/0002-8703(86)90274-7 Schulze, 1990, Antibodies to ADP-ATP carrier – an autoantigen in myocarditis and dilated cardiomyopathy – impair cardiac function, Circulation, 81, 959, 10.1161/01.CIR.81.3.959 Fu, 1993, Location of functional autoimmune epitope on muscarinic acetylcholine receptor-2 in patients with idiopathic dilated cardiomyopathy, J Clin Invest, 91, 1964, 10.1172/JCI116416 Wallukat, 1995, Anti-β1-adrenoceptor antibodies with chronotropic activity from serum of patients with dilated cardionmyopathy: mapping of epitopes in the first and second extra- cellular loops, J Mol Cell Cardiol, 27, 397, 10.1016/S0022-2828(08)80036-3 Caforio, 2002, Circulating cardiac autoantibodies in dilated cardiomyopathy and myocarditis: pathogenic and clinical significance, Eur J Heart Fail, 4, 411, 10.1016/S1388-9842(02)00010-7 Dörfel, 1997, Short term hemodynamic effects of immunoadsorption in dilated cardiomyopathy, Circulation, 95, 1994, 10.1161/01.CIR.95.8.1994 Matsui, 1997, Peptides derived from cardiovascular G-protein-coupled receptors induce morphological cardiomyopathic changes in immunized rabbits, J Mol Cell Cardiol, 29, 641, 10.1006/jmcc.1996.0307 Müller, 2000, Immunoglobulin adsorption in patients with idiopathic dilated cardiomyopathy, Circulation, 101, 385, 10.1161/01.CIR.101.4.385 Felix, 2000, Hemodynamic effects of immunoadsorption and subsequent immunoglobulin substitution in dilated cardiomyopathy: three month results from a randomized study, J Am Coll Cardiol, 35, 1590, 10.1016/S0735-1097(00)00568-4 Knebel, 2004, Reduction of morbidity by immunadsorption therapy in patients with dilated cardiomyopathy, Int J Cardiol, 97, 517, 10.1016/j.ijcard.2003.12.003 Felix, 2002, Removal of cardiodepressant antibodies in dilated cardiomyopathy by immunoadsorbtion, J Am Coll Cardiol, 39, 646, 10.1016/S0735-1097(01)01794-6 Doesch, 2009, Effects of protein A immunoadsorption in patients with advanced chronic dilated cardiomyopathy, J Clin Apher, 24, 141 D'Alonzo, 1991, Survival in patients with primary pulmonary hypertension: results from a national prospective registry, Ann Intern Med, 115, 343, 10.7326/0003-4819-115-5-343 Farber, 2004, Pulmonary arterial hypertension, N Engl J Med, 351, 1655, 10.1056/NEJMra035488 Wallukat, 2007, Agonistic autoantibodies against the endothelin-1 ETA and α-1adrenergic receptor in sera of patients with idiopathic pulmonary arterial hypertension, Circulation, 116, II Dandel, 2008, Potential pathogenetic involvement of agonistic autoantibodies against α1-adrenergic and endothelin-1 receptors in pulmonary arterial hypertension, Circulation, 118, S1072 Sampietro, 2005, Inflammatory markers and serum lipids in idiopathic dilated cardiomyopathy, Am J Cardiol, 96, 1718, 10.1016/j.amjcard.2005.07.093 Yoshikawa, 2009, Autoimmune mechanisms underlying dilated cardiomyopathy, Circ J, 73, 602, 10.1253/circj.CJ-08-1151 Noutsias, 2002, Phenotype characterization in dilated cardiomyopathy – diagnostic significance of T lymphocytes and macrophages in inflammatory cardiomyopathy, Med Sci Monit, 8, CR478 Baba, 2002, Autoantibodies against sarcolemal Na-K-ATPase: possible upstream targets of arrhythmias and sudden deaths in patients with dilated cadiomyopathy, J Am Coll Cardiol, 40, 1153, 10.1016/S0735-1097(02)02075-2 Omerovic, 2000, Induction of cardiomyopathy in severe combined immuno-deficiency mice by transfer of lymphocytes from patients with idiopathic dilated cardiomyopathy, Autoimmunity, 32, 271, 10.3109/08916930008994101 Konstadoulakis, 1993, Clinical significance of antibodies against tropomyosin, actin and myosin in patients with dilated cardiomyopathy, J Clin Lab Immunol, 40, 61 Baba, 2004, Autoantibodies against M2-muscarinic acetylcholine receptors: new upstreams targets in atrial fibrillation in patients with dilated cardiomyopathy, Eur Heart J, 25, 1108, 10.1016/j.ehj.2004.05.012 Lauer, 2000, Antimyosin autoantibodies are associated with deterioration of systolic and diastolic left ventricular function in patients with chronic myocarditis, J Am Coll Cardiol, 35, 11, 10.1016/S0735-1097(99)00485-4 Wallukat, 1987, Effects of serum gamma globulin fraction of patients with allergic asthma and dilated cardiomyopathy on chronotropic β-adrenergic function in cultured rat heart myocytes, Biochim Biomed Acta, 78, 634 Gavin, 2002, Induction of myocarditis and valvulitis in Lewis rats by different epitopes of cardiac myosin and its implications in rheumatic carditis, Am J Pathol, 160, 297, 10.1016/S0002-9440(10)64373-8 Matsui, 2006, Transfer of immune components from rabbit autoimmune cardio – myopathy into severe combined immunodeficiency (SCID) mice induces cardiomyopathic changes, Autoimmunity, 39, 121, 10.1080/08916930500314855 Jahns, 2004, Direct evidence for beta-1 adrenergic receptor directed autoimmune attack as a cause of idiopathic dilated cardiomyopathy, J Clin Invest, 113, 1419, 10.1172/JCI200420149 Cunningham, 1986, A study of antigroup A streptococcal monoclonal antibodies cross-reactive with myosin, J Immunol, 136, 293, 10.4049/jimmunol.136.1.293 Caforio, 1992, Identification of alpha- and beta-cardiac myosin heavy chain isoforms as major antigens in dilated cardiomyopathy, Circulation, 85, 1734, 10.1161/01.CIR.85.5.1734 Li, 2006, Mimicry and antibody-mediated cell signaling in autoimmune myocarditis, J Immunol, 177, 8234, 10.4049/jimmunol.177.11.8234 Staudt, 2003, Beta-1-adrenoceptor autoantibodies induce apoptosis in adult isolated cardiomyocytes, Eur J Pharmacol, 466, 1, 10.1016/S0014-2999(03)01431-6 Horwich, 2003, Cardiac troponin I is associated with impaired hemodynamics, progressive left ventricular dysfunction and increased mortality rates in advanced heart failure, Circulation, 108, 833, 10.1161/01.CIR.0000084543.79097.34 Groser, 2006, Cardiac troponin I but not cardiac troponin T induces severe auto-immune inflammation in the myocardium, Circulation, 114, 1693, 10.1161/CIRCULATIONAHA.106.635664 Shmilowich, 2007, Autoantibodies to cardiac troponin I in patients with idiopathic dilated and ischemic cardiomyopathy, Int J Cardiol, 117, 198, 10.1016/j.ijcard.2006.04.077 Fukada, 2004, Autoimmunity against the second extracellular loop of beta1-adrenergic receptors induces early after-depolarization and decreases in K-channel density in rabbits, J Am Coll Cardiol, 43, 1090, 10.1016/j.jacc.2003.09.057 Jahns, 1999, Autoantibodies activating human beta adrenergic receptors are associated with reduced cardiac function in chronic heart failure, Circulation, 99, 649, 10.1161/01.CIR.99.5.649 Iwata, 2001, Autoantibodies against the second extracellular loop of β1-adrenergic receptors predict ventricular tachycardia and sudden death in patients with idiopathic dilated cardiomyopathy, J Am Coll Cardiol, 37, 418, 10.1016/S0735-1097(00)01109-8 Störk, 2006, Stimulating autoantibodies directed against beta-1 adrenergic receptor predict increased mortality in idiopathic cardiomyopathy, Am Heart J, 152, 697, 10.1016/j.ahj.2006.05.004 Müller, 1997, Weaning from mechanical cardiac support in patients with idiopathic dilated cardiomyopathy, Circulation, 96, 542, 10.1161/01.CIR.96.2.542 Dandel, 2008, Prediction of cardiac stability after weaning from ventricular assist devices in patients with idiopathic dilated cardiomyopathy, Circulation, 118, S94, 10.1161/CIRCULATIONAHA.107.755983 Goodwin, 1985, Mechanisms in cardiomyopathies, J Mol Cell Cardiol, 17, 5, 10.1016/0022-2828(85)90003-3 Maekawa, 2007, Connecting the missing link between dilated cardiomyopathy and viral myocarditis: virus, cytoskeleton, and innate immunity, Circulation, 115, 5, 10.1161/CIRCULATIONAHA.106.670554 Levin, 2008, Cross-talk between anti-β1-adrenoceptor antibodies in dilated cardiomyopathy and Chagas' disease, Autoimmunity, 41, 429, 10.1080/08916930802031702 Jane-wit, 2007, β1-adrenergic receptor autoantibodies mediate dilated cardio- myopathy by agonistic induced apoptosis, Circulation, 116, 399, 10.1161/CIRCULATIONAHA.106.683193 Wallukat, 1999, Agonist like beta-adrenergic antibodies in heart failure, Am J Cardiol, 83, 75H, 10.1016/S0002-9149(99)00265-9 Christ, 2001, Autoantibodies against the beta-1 adrenoceptor prolong action potential duration and enhance contractility in isolated cardiomyocytes, J Mol Cell Cardiol, 33, 1515, 10.1006/jmcc.2001.1414 Nicolls, 2005, Autoimmunity in pulmonary hypertension: a perspective, Eur Respir J, 26, 1110, 10.1183/09031936.05.00045705 Tamby, 2005, Anti-endothelial cell autoantibodies in idiopathic and systemic sclerosis associated pulmonary arterial hypertension, Thorax, 60, 765, 10.1136/thx.2004.029082 Tamby, 2006, Antibodies to fibroblasts in idiopathic and scleroderma-associated pulmonary hypertension, Eur Respir J, 28, 799, 10.1183/09031936.06.00152705 Giaid, 1993, Expression of endothelin 1 in lungs of patients with pulmonary hypertension, N Engl J Med, 328, 1732, 10.1056/NEJM199306173282402 Salvi, 1999, α-1-adrenergic hypothesis for pulmonary hypertension, Cest, 115, 1708 James, 1996, Early effects of total hepatectomy on hemodynamic state and organ uptake of catecholamines in the pig, Brit J Anaesth, 76, 713, 10.1093/bja/76.5.713 Bevan, 1986, Physiological variation in α-adrenoreceptor-mediated arterial sensitivity: relation to agonist affinity, Science, 234, 196, 10.1126/science.3018932 Chen, 2000, Endothelial dysfunction in the pulmonary vascular bed, Am J Med Sci, 320, 223, 10.1097/00000441-200010000-00001 Rich, 2003, Endothelin receptor blockers in cardiovascular disease, Circulation, 108, 2184, 10.1161/01.CIR.0000094397.19932.78 MacLean, 1998, Endothelin-1: a mediator of pulmonary hypertension?, Pulm Pharmacol Ther, 11, 125, 10.1006/pupt.1998.0126 Love, 1996, Vasodilator effects of endothelin-converting enzyme inhibition and endothelin ETA receptor blockade in chronic heart failure patients treated with ACE inhibitors, Circulation, 94, 2131, 10.1161/01.CIR.94.9.2131 Nootens, 1995, Neurohormonal activation in patients with right ventricular failure from pulmonary hypertension: relation to hemodynamic variables and endothelin levels, J Am Coll Cardiol, 26, 1581, 10.1016/0735-1097(95)00399-1 Wallukat, 1996, Removal of autoantibodies in dilated cardiomyopathy by immunoadsorption, Int J Cardiol, 54, 91, 10.1016/0167-5273(96)02598-3 Schimke, 2001, Decreased oxidative stress in patients with idiopathic dilated cardiomyopathy: one year after immunoglobulin adsorption, J Am Coll Cardiol, 38, 178, 10.1016/S0735-1097(01)01309-2 Mobini, 2003, Hemodynamic improvement and removal of autoantibodies against beta-1-adrenergic receptor by immunoadsorption therapy in dilated cardiomyopathy, J Autoimmun, 20, 345, 10.1016/S0896-8411(03)00042-8 Staudt, 2005, Role of immunoglobulin G3 subclass in dilated cardiomyopathy: results from protein A immunoadsorption, Am Heart J, 150, 729, 10.1016/j.ahj.2004.11.002 Staudt, 2006, Immunoadsorption in dilated cardiomyopahy: 6 months results from a randomized study, Am Heart J, 152, 10.1016/j.ahj.2006.06.027 Herda, 2010, Effects of immunoadsorption and subsequent immunoglobulin G substitution on cardiopulmonary exercise capacity in patients with dilated cardiomyopathy, Am Heart J, 159, 809, 10.1016/j.ahj.2010.01.012 Dörfel, 2004, Immunoadsorption in dilated cardiomyopathy, a 3 year follow-up, Int J Cardiol, 97, 529, 10.1016/j.ijcard.2004.03.001 Dandel, 2010, Efficacy of immunoadsorption as bridge-to-transplant therapy in patients with idiopathic dilated cardiomyopathy and evidence of beta-1 adrenoceptor autoantibodies, J Heart Lung Transplant, 29, 163, 10.1016/j.healun.2009.11.518 Staudt, 2010, Fcγ-receptor IIa polymorphism and the role of immunoadsorption in cardiac dysfunction in patients with dilated cardiomyopathy, Clin Pharamcol Ther, 87, 452, 10.1038/clpt.2009.246 Dandel, 2010, Are the therapeutic benefits of extracorporeal immunoglobulin adsorption in beta-1 adrenoceptor autoantibody positive patients with dilated cardiomyopathy indeed related to the removal of these antibodies?, Circulation, 122, A10319 Dandel, 2012, Role of β1 adrenoceptor autoantibodies in the pathogenesis of dilated cardiomyopathy, Immunobiology, 217, 511, 10.1016/j.imbio.2011.07.012 Felix, 2008, Immunoadsorption as treatment option in dilated cardiomyopathy, Autoimmunity, 41, 484, 10.1080/08916930802031173 Ikeda, 2008, Immunoadsorbtion therapy for patients with dilated cardiomyopathy and heart failure, Curr Cardiol Rev, 4, 219, 10.2174/157340308785160534 Staudt, 2001, Immunohistological changes in dilated cardiomyopathy induced by immunoadsorption therapy and subsequent immunoglobulin substitution, Circulation, 103, 2681, 10.1161/01.CIR.103.22.2681 Cooper, 2007, A pilot study to asses the use of protein A immunoadsorption for chronic dilated cardiomyopathy, J Clin Apher, 22, 210, 10.1002/jca.20130 Dandel, 2009, Functional autoantibodies against G-protein coupled receptors in sera of patients with pulmonary arterial hypertension: potential involvement in the pathogenesis of the disease, J Am Coll Cardiol, 53, A454 Dandel, 2009, Autoantibodies against endothelin-1 receptors are involved in the pathogenesis of pulmonary arterial hypertension, Circulation, 120, S1134