Imaging of intracranial hemorrhage in photon counting computed tomography using virtual monoenergetic images

Denise Schoenbeck1,2, Alexander Sacha1,2, Julius Henning Niehoff1,2, Christoph Moenninghoff1,2, Jan Borggrefe1,2, Sebastian Horstmeier1,2, Alexey Surov1,2, Iram Shahzadi3, Ulrich Knappe2,4, Jan Robert Kroeger1,2, Arwed Elias Michael1,2
1Department of Radiology, Neuroradiology and Nuclear Medicine, Johannes Wesling University Hospital, Ruhr University Bochum, Bochum, Germany
2Johannes Wesling University Hospital By Muehlenkreiskliniken AöR, Minden, Germany
3Siemens Healthineers GmbH, Erlangen, Germany
4Department of Neurosurgery, Johannes Wesling University Hospital, Ruhr University Bochum, Bochum, Germany

Tóm tắt

To determine the optimal virtual monoenergetic image (VMI) for detecting and assessing intracranial hemorrhage in unenhanced photon counting CT of the head based on the evaluation of quantitative and qualitative image quality parameters. Sixty-three patients with acute intracranial hemorrhage and unenhanced CT of the head were retrospectively included. In these patients, 35 intraparenchymal, 39 intraventricular, 30 subarachnoidal, and 43 subdural hemorrhages were selected. VMIs were reconstructed using all available monoenergetic reconstruction levels (40–190 keV). Multiple regions of interest measurements were used for evaluation of the overall image quality, and signal, noise, signal-to-noise-ratio (SNR), and contrast-to-noise-ratio (CNR) of intracranial hemorrhage. Based on the results of the quantitative analysis, specific VMIs were rated by five radiologists on a 5-point Likert scale. Signal, noise, SNR, and CNR differed significantly between different VMIs (p < 0.001). Maximum CNR for intracranial hemorrhage was reached in VMI with keV levels > 120 keV (intraparenchymal 143 keV, intraventricular 164 keV, subarachnoidal 124 keV, and subdural hemorrhage 133 keV). In reading, no relevant superiority in the detection of hemorrhage could be demonstrated using VMIs above 66 keV. For the detection of hemorrhage in unenhanced CT of the head, the quantitative analysis of the present study on photon counting CT is generally consistent with the findings from dual-energy CT, suggesting keV levels just above 120 keV and higher depending on the location of the hemorrhage. However, on the basis of the qualitative analyses, no reliable statement can yet be made as to whether an additional VMI with higher keV is truly beneficial in everyday clinical practice.

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Tài liệu tham khảo

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