Il Progetto Ipertensione negli Accordi Integrativi Locali fra FIMMG e AUSL di Ferrara: i risultati di un’esperienza

PharmacoEconomics Italian Research Articles - Tập 11 - Trang 165-173 - 2009
G. R. Marinelli1, C. Casaroli1, N. Vita1, R. Finessi1, A. Fiorini1, F. Levato1, A. Campi1, F. Foglietta1, G. L. Colombo2
1AUSL Ferrara, Italia
2S.A.V.E. Studi Analisi Valutazioni Economiche, Milano, Italia

Tóm tắt

Cardiovascular disease (CV) is the most common cause of death and permanent disability in industrialized countries and hypertension is among the most important CV risk factors. From 2001 to 2007, the Ferrara Local Health Authority (AUSL) in collaboration with the Italian Federation of Family Doctors (FIMMG) within the Local Supplementary Agreements (AIL), developed a working plan known as “Hypertension Project” aiming to improve the prescription appropriateness of antihypertensive drugs. An indicator measuring adherence of General Practitioners (GPs) to correct prescription of antihypertensive drugs was defined. The indicator was the Mean Cost of Defined Daily Dose (DDD) for antihypertensive drugs (MC-DDD-A) per GP, calculated as the total cost for antihypertensives during the time period considered divided by the total number of DDD of antihypertensives used in the same period. Since 2003 expenditure for antihypertensive drugs has stabilized reaching an annual amount of €21,500,000.00, whereas from 2000 to 2002 the trend indicated an increase by €1,750,000.00 yearly. Actually, the MC-DDD-A of the Ferrara AUSL decreased from €0.54 in 2003 to €0.41 in 2007 compared to €0.50 and €0.46 of the Emilia Romagna Region. With regard to consequences on healthcare, in the same period (2003–2007) the DDD/1,000 persons/die of antihypertensive drugs decreased from 298 to 385 with a concomitant increase of DDD/1,000 persons/die of (less expensive) first choice antihypertensive drugs. The “Hypertension Project” — which meets the principles of medical ethics and deontology — favoured greater adherence to the agreed objectives of appropriateness for the use of antihypertensive drugs and a more rational utilization of available resources, allowing a more extensive use of antihypertensive drugs without increasing healthcare expenditure.

Tài liệu tham khảo

Borgonovi E, Longo F. Riforma sanitaria e medicina generale in Italia. In: Sassi F, (ed). Gestione e finanziamento della medicina generale in Italia. Bologna: Il Mulino Editore, 1997 Sturm H, Austvoll-Dahlgren A, Aaserud M, et al. Pharmaceutical policies: effects of financial incentives for prescribers. Cochrane Database Syst Re 2007: CD006731 Vendramini E. Primary care: role and organization of the general practitioner. In: Lega F, (ed). Organizational design and development for health care services. Mc Graw Hill, 2005 Mancia G, Volpe R, Boros S, et al. Cardiovascular risk profile and blood pressure control in Italian hypertensive patients under specialist care. J Hypertens 2004; 22: 51–7 Wolf-Mayer K, Cooper RS, Banegas JR, et al. Hypertension prevalence and blood pressure levels in 6 European countries, Canada and the United States. JAMA 2003; 289: 2363–9 Levy D, Larson MG, Vasan RS, et al. The progression from hypertension to congestive heart failure. JAMA 1996; 275: 1557–62 Agabiti-Rosei E, Giovannini E, Mancia G, et al. Ipertensione arteriosa e patologia cardiaca. Linee guida diagnostico-terapeutiche a cura della Commissione congiunta ANMCO-SIC-SIIA. G Ital Cardiol 1999; 29: 341–56 Marzari C, Maggi S, Manzato E, et al. Depressive symptoms and development of coronary heart disease events: the Italian Longitudinal Study on Aging (ILSA). J Gerontol 2005; 60A: 85–92 EUROASPIRE I and II Group. European Action on Secondary Prevention by Intervention to Reduce Events. Clinical reality of coronary prevention guidelines: a comparison of EUROASPIRE I and II in nine countries. EUROASPIRE I and II Group. European Action Secondary Prevention by Intervention to Reduce Events. Lancet 2001; 357: 995–1001 Ministero della Salute. Suppl. G.U.-Serie generale-N. 4 del 7 gennaio 2003; D.M. del 20 dicembre 2002 Osservazioni dell’OMS, Allegato 1 al D.M. 27 settembre 2002 Commissione unica del farmaco (CUF). Suppl. ordinario N. 127 G.U. — Serie generale-N. 155 del 5 luglio 1999. “Categorie terapeutiche omogenee” ai sensi del disposto di cui all’art. 36, commi 8 e 16, della legge del 27 dicembre 1997, N. 449 Vaccheri A, Montanaro N. Il metodo della dose definita giornaliera (DDD) per valutare il consumo dei farmaci. Farmeconomia 1995; 3: 16–22 Ezzati M, Lopez AD, Rodgers A, et al. Selected major risk factors and global and regional burden of disease. Lancet 2002; 360: 1347–60 OSMED. L’uso dei farmaci in Italia. Rapporto Nazionale 2007. Roma: AIFA, 2008 Eandi M. Unità di consumo dei farmaci e valutazioni farmacoeconomiche: uso e misuso di DDD e PDD. Farmeconomia e Percorsi Terapeutici 2002; 3: 209–22