Identification of the HECT domain binding of indole-3-carbinol (I3C) derivatives for breast cancer therapy

Phytochemistry Letters - Tập 54 - Trang 7-13 - 2023
Wenwen Zheng1,2, Zhichao Shi1,2, Xun Zhang3, Weibin Wu2, Zigao Yuan3, Lei Zhao4, Qinyuan Li3, Zixuan Qiu5, Cunlong Zhang2, Bizhu Chu4, Zijian Liu2, Wei-Min Chen1, Yuyang Jiang3,4,5,6
1College of Pharmacy, Jinan University, Guangzhou 510632, PR China
2Shenzhen Kivita Innovative Drug Discovery Institute, Shenzhen 518057, PR China
3State Key Laboratory of Chemical Oncogenomics, Guangdong Provincial Key Laboratory of Chemical Biology, Tsinghua Shenzhen International Graduate School, Shenzhen 518055, PR China
4School of Pharmaceutical Sciences, Health Science Center, Shenzhen University, Shenzhen 518060, PR China
5Institute of Biomedical Health Technology and Engineering, Shenzhen Bay Laboratory, Shenzhen, 518132, PR China
6School of Pharmaceutical Sciences, Tsinghua University, Beijing 100084, PR China

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