Identification of the HECT domain binding of indole-3-carbinol (I3C) derivatives for breast cancer therapy
Tài liệu tham khảo
Ai, 2016, Discovery of covalent ligands via noncovalent docking by dissecting covalent docking based on a "steric-clashes alleviating receptor (SCAR)" strategy, J. Chem. Inf. Model, 56, 1563, 10.1021/acs.jcim.6b00334
Anderton, 2004, Pharmacokinetics and tissue disposition of indole-3-carbinol and its acid condensation products after oral administration to mice, Clin. Cancer Res, 10, 5233, 10.1158/1078-0432.CCR-04-0163
Aronchik, 2014, The antiproliferative response of indole-3-carbinol in human melanoma cells is triggered by an interaction with NEDD4-1 and disruption of wild-type PTEN degradation, Mol. Cancer Res, 12, 1621, 10.1158/1541-7786.MCR-14-0018
Bartek, 2001, Mammalian G1- and S-phase checkpoints in response to DNA damage, Curr. Opin. Cell Biol., 13, 738, 10.1016/S0955-0674(00)00280-5
Bernassola, 2008, The HECT family of E3 ubiquitin ligases: multiple players in cancer development, Cancer Cell, 14, 10, 10.1016/j.ccr.2008.06.001
Bernassola, 2019, HECT-type E3 ubiquitin ligases in cancer, Trends Biochem Sci., 44, 1057, 10.1016/j.tibs.2019.08.004
Caruso, 2014, Indole-3-carbinol and its N-alkoxy derivatives preferentially target ERalpha-positive breast cancer cells, Cell Cycle, 13, 2587, 10.4161/15384101.2015.942210
Chen, 2021, A cell-free nanobody engineering platform rapidly generates SARS-CoV-2 neutralizing nanobodies, Nat. Commun., 12, 5506, 10.1038/s41467-021-25777-z
Choudhari, 2019, Phytochemicals in cancer treatment: from preclinical studies to clinical practice, Front. Pharmacol., 10, 1614, 10.3389/fphar.2019.01614
Cram, 2001, Indole-3-carbinol inhibits CDK6 expression in human MCF-7 breast cancer cells by disrupting Sp1 transcription factor interactions with a composite element in the CDK6 gene promoter, J. Biol. Chem., 276, 22332, 10.1074/jbc.M010539200
Fuentes, 2015, Dietary glucosinolates sulforaphane, phenethyl isothiocyanate, Indole-3-Carbinol/3,3′-diindolylmethane: anti-oxidative stress/inflammation, Nrf2, epigenetics/epigenomics and in vivo cancer chemopreventive efficacy, Curr. Pharmacol. Rep., 1, 179, 10.1007/s40495-015-0017-y
Hong, 2020, Late-stage diversification of natural products, ACS Cent. Sci., 6, 622, 10.1021/acscentsci.9b00916
Huang, 2020, Exosomal circRNA-100338 promotes hepatocellular carcinoma metastasis via enhancing invasiveness and angiogenesis, J. Exp. Clin. Cancer Res, 39, 20, 10.1186/s13046-020-1529-9
Jiang, 2019, Anti-Cancer Effects of 3, 3′-diindolylmethane on human hepatocellular carcinoma cells is enhanced by calcium ionophore: the role of cytosolic Ca(2+) and p38 MAPK, Front. Pharmacol., 10, 1167, 10.3389/fphar.2019.01167
Karimabad, 2019, Molecular targets, anti-cancer properties and potency of synthetic indole-3-carbinol derivatives, Mini Rev. Med. Chem., 19, 540, 10.2174/1389557518666181116120145
Kathman, 2015, A small molecule that switches a ubiquitin ligase from a processive to a distributive enzymatic mechanism, J. Am. Chem. Soc., 137, 12442, 10.1021/jacs.5b06839
Kim, 2018, Current results on the biological and pharmacological activities of Indole-3-carbinol, EXCLI J., 17, 181
Kishikawa, 2021, WWP1 inactivation enhances efficacy of PI3K inhibitors while suppressing their toxicities in breast cancer models, J. Clin. Invest, 131
Lee, 2018, Indole-3-carbinol induces apoptosis in human hepatocellular carcinoma Huh-7cells, Food Chem. Toxicol., 118, 119, 10.1016/j.fct.2018.05.014
Lee, 2019, Anticarcinogenic effect of indole-3-carbinol (I3C) on human hepatocellular carcinoma SNU449 cells, Hum. Exp. Toxicol., 38, 136, 10.1177/0960327118785235
Lee, 2020, WWP1 Gain-of-Function Inactivation of PTEN in Cancer Predisposition, N. Engl. J. Med, 382, 2103, 10.1056/NEJMoa1914919
Martinez Molina, 2013, Monitoring drug target engagement in cells and tissues using the cellular thermal shift assay, Science, 341, 84, 10.1126/science.1233606
Maruthanila, 2014, Attenuation of carcinogenesis and the mechanism underlying by the influence of indole-3-carbinol and its metabolite 3,3′-diindolylmethane: a therapeutic marvel, Adv. Pharmacol. Sci., 2014
Megna, 2016, Indole-3-carbinol induces tumor cell death: function follows form, J. Surg. Res, 204, 47, 10.1016/j.jss.2016.04.021
Moiseeva, 2006, Indole-3-carbinol-induced death in cancer cells involves EGFR downregulation and is exacerbated in a 3D environment, Apoptosis, 11, 799, 10.1007/s10495-006-5877-5
Nguyen, 2010, 1-Benzyl-indole-3-carbinol is a novel indole-3-carbinol derivative with significantly enhanced potency of anti-proliferative and anti-estrogenic properties in human breast cancer cells, Chem. Biol. Interact., 186, 255, 10.1016/j.cbi.2010.05.015
Oliver, 1998, Importance of poly(ADP-ribose) polymerase and its cleavage in apoptosis. Lesson from an uncleavable mutant, J. Biol. Chem., 273, 33533, 10.1074/jbc.273.50.33533
Quirit, 2017, Indole-3-carbinol (I3C) analogues are potent small molecule inhibitors of NEDD4-1 ubiquitin ligase activity that disrupt proliferation of human melanoma cells, Biochem. Pharmacol., 127, 13, 10.1016/j.bcp.2016.12.007
Reekie, 2017, Rapid access to N-(indol-2-yl)amides and N-(indol-3-yl)amides as unexplored pharmacophores, Org. Biomol. Chem., 15, 576, 10.1039/C6OB02622B
Smaill, 2016, Tyrosine Kinase inhibitors. 20. optimization of substituted quinazoline and pyrido[3,4-d]pyrimidine derivatives as orally active, irreversible inhibitors of the epidermal growth factor receptor family, J. Med. Chem., 59, 8103, 10.1021/acs.jmedchem.6b00883
Song, 2021, The HECT family of E3 ubiquitin ligases and PTEN, Semin. Cancer Biol.
Sreenivasulu, 2019, Synthesis, antiproliferative and apoptosis induction potential activities of novel bis(indolyl)hydrazide-hydrazone derivatives, Bioorg. Med. Chem., 27, 1043, 10.1016/j.bmc.2019.02.002
Wang, 2021, Combined luteolin and indole-3-carbinol synergistically constrains eralpha-positive breast cancer by dual inhibiting estrogen receptor alpha and cyclin-dependent kinase 4/6 pathway in cultured cells and xenograft mice, Cancers, 13
Weng, 2007, A potent indole-3-carbinol derived antitumor agent with pleiotropic effects on multiple signaling pathways in prostate cancer cells, Cancer Res, 67, 7815, 10.1158/0008-5472.CAN-07-0794
Weng, 2008, Indole-3-carbinol as a chemopreventive and anti-cancer agent, Cancer Lett., 262, 153, 10.1016/j.canlet.2008.01.033
Wu, 2019, Inhibition of tumor growth by dietary indole-3-carbinol in a prostate cancer xenograft model may be associated with disrupted gut microbial interactions, Nutrients, 11
Xie, 2015, Design, synthesis of novel tryptophan derivatives for antiplatelet aggregation activity based on tripeptide pENW (pGlu-Asn-Trp), Eur. J. Med. Chem., 102, 363, 10.1016/j.ejmech.2015.07.016
Zhao, 2021, Design, synthesis and evaluation of novel ErbB/HDAC multitargeted inhibitors with selectivity in EGFR(T790M) mutant cell lines, Eur. J. Med. Chem., 213, 10.1016/j.ejmech.2021.113173
Zubair, 2017, Cancer chemoprevention by phytochemicals: nature's healing touch, Molecules, 22