Identification of candidate genes affecting Δ9-tetrahydrocannabinol biosynthesis in Cannabis sativa
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2006, Active site residues governing substrate selectivity and polyketide chain length in aloesone synthase, FEBS Journal, 273, 208, 10.1111/j.1742-4658.2005.05059.x
2008, Antibacterial cannabinoids from Cannabis sativa: a structure–activity study, Journal of Natural Products, 71, 1427, 10.1021/np8002673
2000, Gene ontology: tool for the unification of biology. The gene ontology consortium, Nature Genetics, 25, 25, 10.1038/75556
2003, The chalcone synthase superfamily of type III polyketide synthases, Natural Product Reports, 20, 79, 10.1039/b100917f
2003, The therapeutic potential of cannabis, Lancet Neurology, 2, 291, 10.1016/S1474-4422(03)00381-8
2002, Phytochelatins and metallothioneins: roles in heavy metal detoxification and homeostasis, Annual Review of Plant Biology, 53, 159, 10.1146/annurev.arplant.53.100301.135154
2004, On the origin of the fig: phylogenetic relationships of Moraceae from ndhF sequences, American Journal of Botany, 91, 767, 10.3732/ajb.91.5.767
2006, Genetic variation in hemp and marijuana (Cannabis sativa L.) according to amplified fragment length polymorphisms, Journal of Forensic Sciences, 51, 371, 10.1111/j.1556-4029.2006.00061.x
2003, The inheritance of chemical phenotype in Cannabis sativa L, Genetics, 163, 335, 10.1093/genetics/163.1.335
1998, The deoxyxylulose phosphate pathway of terpenoid biosynthesis in plants and microorganisms, Chemical Biology, 5, R221, 10.1016/S1074-5521(98)90002-3
2000, Potency trends of Delta(9)-THC and other cannabinoids in confiscated marijuana from 1980–1997, Journal of Forensic Sciences, 45, 24, 10.1520/JFS14636J
2001, Biosynthesis of cannabinoids. Incorporation experiments with (13)C-labeled glucoses, European Journal of Biochemistry, 268, 1596, 10.1046/j.1432-1327.2001.02030.x
1998, Prenylation of olivetolate by a hemp transferase yields cannabigerolic acid, the precursor of tetrahydrocannabinol, FEBS Letters, 427, 283, 10.1016/S0014-5793(98)00450-5
2008, PKS activities and biosynthesis of cannabinoids and flavonoids in Cannabis sativa L. plants, Plant and Cell Physiology, 49, 1767, 10.1093/pcp/pcn150
2005, Metabolic, genomic, and biochemical analyses of glandular trichomes from the wild tomato species Lycopersicon hirsutum identify a key enzyme in the biosynthesis of methylketones, The Plant Cell, 17, 1252, 10.1105/tpc.104.029736
2001, An investigation of the storage and biosynthesis of phenylpropenes in sweet basil, Plant Physiology, 125, 539, 10.1104/pp.125.2.539
2002, Identification, structure, and differential expression of members of a BURP domain containing protein family in soybean, Genome, 45, 693, 10.1139/g02-032
2005, DATF: a database of Arabidopsis transcription factors, Bioinformatics, 21, 2568, 10.1093/bioinformatics/bti334
1977, Morphogenesis of capitate glandular hairs of Cannabis sativa (Cannabaceae), American Journal of Botany, 64, 1023, 10.2307/2442258
1978, Ultrastructural development of capitate glandular hairs of Cannabis sativa L. (Cannabaceae), American Journal of Botany, 65, 140, 10.2307/2442447
1999, Biosynthesis of so-called ‘green odor’ emitted by green leaves, Comprehensive natural products chemistry
2009, Prenyl transfer to aromatic substrates: genetics and enzymology, Current Opinion in Chemical Biology, 13, 171, 10.1016/j.cbpa.2009.02.020
2004, A chemotaxonomic analysis of cannabinoid variation in Cannabis (Cannabaceae), American Journal of Botany, 91, 966, 10.3732/ajb.91.6.966
2000, Dissection of malonyl-coenzyme A decarboxylation from polyketide formation in the reaction mechanism of a plant polyketide synthase, Biochemistry, 39, 890, 10.1021/bi991489f
1997, Immunochemical localization of tetrahydrocannabinol (THC) in cryofixed glandular trichomes of Cannabis (Cannabaceae), American Journal of Botany, 84, 336, 10.2307/2446007
2003, Secretory vesicle formation in the secretory cavity of glandular trichomes of Cannabis sativa L. (Cannabaceae), Molecules and Cells, 15, 387, 10.1016/S1016-8478(23)13755-1
2008, Quality of chemically modified hemp fibres, Bioresource Technology, 99, 94, 10.1016/j.biortech.2006.11.050
1994, A pathway for the biosynthesis of straight and branched, odd- and even-length, medium-chain fatty acids in plants, Proceedings of the National Academy of Sciences, USA, 91, 11437, 10.1073/pnas.91.24.11437
2000, Probing essential oil biosynthesis and secretion by functional evaluation of expressed sequence tags from mint glandular trichomes, Proceedings of the National Academy of Sciences, USA, 97, 2934, 10.1073/pnas.97.6.2934
2006, Cannabidiol reverses MK-801-induced disruption of prepulse inhibition in mice, Neuropsychopharmacology, 31, 795, 10.1038/sj.npp.1300838
2008, AtMYB12 regulates caffeoyl quinic acid and flavonol synthesis in tomato: expression in fruit results in very high levels of both types of polyphenol, The Plant Journal, 56, 316, 10.1111/j.1365-313X.2008.03597.x
2007, Genetic interaction between glabra3-shapeshifter and siamese in Arabidopsis thaliana converts trichome precursors into cells with meristematic activity, The Plant Journal, 522, 352
2009, Transcritptome analysis of Arabidopsis wild type and gl3-sst sim trichomes identifies four additional genes required for trichome development, Molecular Plant, 2
1994, The normalization of recreational drug use amongst young people in north-west England, British Journal of Sociology, 45, 287, 10.2307/591497
2005, Plant cannabinoids: a neglected pharmacological treasure trove, British Journal of Pharmacology, 146, 913, 10.1038/sj.bjp.0706415
2005, The Arabidopsis transcription factor MYB12 is a flavonol-specific regulator of phenylpropanoid biosynthesis, Plant Physiology, 138, 1083, 10.1104/pp.104.058032
2003, The BOTRYTIS SUSCEPTIBLE1 gene encodes an R2R3MYB transcription factor protein that is required for biotic and abiotic stress responses in Arabidopsis, The Plant Cell, 15, 2551, 10.1105/tpc.014167
2008, EST analysis of hop glandular trichomes identifies an O-methyltransferase that catalyses the biosynthesis of xanthohumol, The Plant Cell, 20, 186, 10.1105/tpc.107.055178
2001, Cloning and analysis of valerophenone synthase gene expressed specifically in lupulin gland of hop (Humulus lupulus L.), Bioscience, Biotechnology and Biochemistry, 65, 150, 10.1271/bbb.65.150
2006, Genetics and marker-assisted selection of the chemotype in Cannabis sativa L, Molecular Breeding, 17, 257, 10.1007/s11032-005-5681-x
2006, Cannabinoid pharmacology: the first 66 years, British Journal of Pharmacology, 147, S163, 10.1038/sj.bjp.0706406
2004, Olivetol as product of a polyketide synthase in Cannabis sativa L, Plant Science, 166, 381, 10.1016/j.plantsci.2003.09.027
2004, Cloning and over-expression of a cDNA encoding a polyketide synthase from Cannabis sativa, Plant Physiology and Biochemistry, 42, 291, 10.1016/j.plaphy.2004.02.011
2004, Comparative proteomics of Cannabis sativa plant tissues, Journal of Biomolecular Technology, 15, 97
1999, The discovery of a mevalonate-independent pathway for isoprenoid biosynthesis in bacteria, algae and higher plants, Natural Products Reports, 16, 565, 10.1039/a709175c
1989, Molecular cloning: a laboratory manual
2004, The gene controlling marijuana psychoactivity: molecular cloning and heterologous expression of Delta1-tetrahydrocannabinolic acid synthase from Cannabis sativa L, Journal of Biological Chemistry, 279, 39767, 10.1074/jbc.M403693200
2005, Tetrahydrocannabinolic acid synthase, the enzyme controlling marijuana psychoactivity, is secreted into the storage cavity of the glandular trichomes, Plant and Cell Physiology, 46, 1578, 10.1093/pcp/pci166
2007, A polyketide synthase of Plumbago indica that catalyses the formation of hexaketide pyrones, FEBS Journal, 274, 406, 10.1111/j.1742-4658.2006.05588.x
2004, Xanthohumol and related prenylflavonoids from hops and beer: to your good health!, Phytochemistry, 65, 1317, 10.1016/j.phytochem.2004.04.025
2001, The R2R3-MYB gene family in Arabidopsis thaliana, Current Opinion in Plant Biology, 4, 447, 10.1016/S1369-5266(00)00199-0
2007, Cannabidiolic-acid synthase, the chemotype-determining enzyme in the fibre-type Cannabis sativa, FEBS Letters, 581, 2929, 10.1016/j.febslet.2007.05.043
1980, Constituents of Cannabis sativa L. XVIII–Electron voltage selected ion monitoring study of cannabinoids, Biomedical Mass Spectrometry, 7, 247, 10.1002/bms.1200070605
2004, Synergistic antifungal activity of two chitin-binding proteins from spindle tree (Euonymus europaeus L.), Planta, 219, 221, 10.1007/s00425-004-1238-1
2008, Terpene biosynthesis in glandular trichomes of hop, Plant Physiology, 148, 1254, 10.1104/pp.108.125187
2005, Safety issues concerning the medical use of cannabis and cannabinoids, Pain Research Management, 10
1993, The plant hormone abscisic acid mediates the drought-induced expression but not the seed-specific expression of rd22, a gene responsive to dehydration stress in Arabidopsis thaliana, Molecular and General Genetics, 238, 17