Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase

Molecular and Cellular Neurosciences - Tập 14 Số 6 - Trang 419-427 - 1999
Ishrut Hussain1, David J. Powell2, David Howlett1, David G. Tew3, Thomas D. Meek3, C.G. Chapman4, Israel Gloger4, Kay E. Murphy4, Christopher Southan5, Dominic M. Ryan6, Trudi S. Smith7, David L. Simmons1, Frank S. Walsh1, Colin Dingwall1, Gary Christie1
1Department of Neurosciences, SmithKline Beecham Pharmaceuticals, New Frontiers Science Park, (North), Coldharbour Road, Fourth Avenue, Harlow, Essex CM19 5AW, United Kingdom
2Department of Molecular Screening Technologies, SmithKline Beecham Pharmaceuticals, New Frontiers Science Park, (North), Coldharbour Road, Fourth Avenue, Harlow, Essex CM19 5AW, United Kingdom
3Department of Molecular Screening Technologies, SmithKline Beecham Pharmaceuticals, 709 Swedeland Road, King of Prussia, Pennsylvania, 19406
4Department of Biotechnology and Genetics, SmithKline Beecham Pharmaceuticals, New Frontiers Science Park, (North), Coldharbour Road, Fourth Avenue, Harlow, Essex CM19 5AW, United Kingdom
5Department of Bioinformatics, SmithKline Beecham Pharmaceuticals, New Frontiers Science Park, (North), Coldharbour Road, Fourth Avenue, Harlow, Essex CM19 5AW, United Kingdom
6Department of Medicinal Chemistry, SmithKline Beecham Pharmaceuticals, New Frontiers Science Park, (North), Coldharbour Road, Fourth Avenue, Harlow, Essex CM19 5AW, United Kingdom
7Department of Biotechnology and Genetics, SmithKline Beecham Pharmaceuticals, 709 Swedeland Road, King of Prussia, Pennsylvania, 19406

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