Identification of a Multipotent Self-Renewing Stromal Progenitor Population during Mammalian Kidney Organogenesis

Elsevier BV - Tập 3 Số 4 - Trang 650-662 - 2014
Akio Kobayashi1,2,3, Joshua W. Mugford1, A. Michaela Krautzberger4,1, Natalie Naiman3, Jessica Liao3, Andrew P. McMahon4,1,2
1Department of Stem Cell and Regenerative Biology, Harvard University, 7 Divinity Avenue, Cambridge, MA 02138, USA
2Harvard Stem Cell Institute, 1350 Massachusetts Avenue, Cambridge, MA 02138, USA
3Renal Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 4 Blackfan Circle, Boston, MA 02115, USA
4Department of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, W. M. Keck School of Medicine, University of Southern California, Los Angeles, 1425 San Pablo Street, Los Angeles, CA 90089, USA

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Bohnenpoll, 2013, Tbx18 expression demarcates multipotent precursor populations in the developing urogenital system but is exclusively required within the ureteric mesenchymal lineage to suppress a renal stromal fate, Dev. Biol., 380, 25, 10.1016/j.ydbio.2013.04.036

Boyle, 2008, Fate mapping using Cited1-CreERT2 mice demonstrates that the cap mesenchyme contains self-renewing progenitor cells and gives rise exclusively to nephronic epithelia, Dev. Biol., 313, 234, 10.1016/j.ydbio.2007.10.014

Boyle, 2014, Notch signaling is required for the formation of mesangial cells from a stromal mesenchyme precursor during kidney development, Development, 141, 346, 10.1242/dev.100271

Brenner-Anantharam, 2007, Tailbud-derived mesenchyme promotes urinary tract segmentation via BMP4 signaling, Development, 134, 1967, 10.1242/dev.004234

Brunskill, 2008, Atlas of gene expression in the developing kidney at microanatomic resolution, Dev. Cell, 15, 781, 10.1016/j.devcel.2008.09.007

Brunskill, 2011, Defining the molecular character of the developing and adult kidney podocyte, PLoS ONE, 6, e24640, 10.1371/journal.pone.0024640

Carroll, 2005, Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital system, Dev. Cell, 9, 283, 10.1016/j.devcel.2005.05.016

Costantini, 2006, Renal branching morphogenesis: concepts, questions, and recent advances, Differentiation, 74, 402, 10.1111/j.1432-0436.2006.00106.x

Costantini, 2010, Patterning a complex organ: branching morphogenesis and nephron segmentation in kidney development, Dev. Cell, 18, 698, 10.1016/j.devcel.2010.04.008

Das, 2013, Stromal-epithelial crosstalk regulates kidney progenitor cell differentiation, Nat. Cell Biol., 15, 1035, 10.1038/ncb2828

Dressler, 2009, Advances in early kidney specification, development and patterning, Development, 136, 3863, 10.1242/dev.034876

Fetting, 2014, FOXD1 promotes nephron progenitor differentiation by repressing decorin in the embryonic kidney, Development, 141, 17, 10.1242/dev.089078

Guillaume, 2009, Paraxial mesoderm contributes stromal cells to the developing kidney, Dev. Biol., 329, 169, 10.1016/j.ydbio.2009.02.034

Harding, 2011, The GUDMAP database—an online resource for genitourinary research, Development, 138, 2845, 10.1242/dev.063594

Hatini, 1996, Essential role of stromal mesenchyme in kidney morphogenesis revealed by targeted disruption of Winged Helix transcription factor BF-2, Genes Dev., 10, 1467, 10.1101/gad.10.12.1467

Herzlinger, 1995, Inductive interactions during kidney development, Semin. Nephrol., 15, 255

Humphreys, 2008, Intrinsic epithelial cells repair the kidney after injury, Cell Stem Cell, 2, 284, 10.1016/j.stem.2008.01.014

Humphreys, 2010, Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis, Am. J. Pathol., 176, 85, 10.2353/ajpath.2010.090517

Indra, 1999, Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases, Nucleic Acids Res., 27, 4324, 10.1093/nar/27.22.4324

Karner, 2011, Canonical Wnt9b signaling balances progenitor cell expansion and differentiation during kidney development, Development, 138, 1247, 10.1242/dev.057646

Kobayashi, 2004, Requirement of Lim1 for female reproductive tract development, Development, 131, 539, 10.1242/dev.00951

Kobayashi, 2005, Distinct and sequential tissue-specific activities of the LIM-class homeobox gene Lim1 for tubular morphogenesis during kidney development, Development, 132, 2809, 10.1242/dev.01858

Kobayashi, 2008, Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development, Cell Stem Cell, 3, 169, 10.1016/j.stem.2008.05.020

Kobayashi, 2011, β-Catenin is essential for Müllerian duct regression during male sexual differentiation, Development, 138, 1967, 10.1242/dev.056143

Levinson, 2003, Stromal progenitors are important for patterning epithelial and mesenchymal cell types in the embryonic kidney, Semin. Cell Dev. Biol., 14, 225, 10.1016/S1084-9521(03)00025-9

Levinson, 2005, Foxd1-dependent signals control cellularity in the renal capsule, a structure required for normal renal development, Development, 132, 529, 10.1242/dev.01604

Lin, 2014, RBP-J in FOXD1+ renal stromal progenitors is crucial for the proper development and assembly of the kidney vasculature and glomerular mesangial cells, Am. J. Physiol. Renal Physiol., 306, F249, 10.1152/ajprenal.00313.2013

Little, 2012, Mammalian kidney development: principles, progress, and projections, Cold Spring Harb. Perspect. Biol., 4, a008300, 10.1101/cshperspect.a008300

Little, 2007, A high-resolution anatomical ontology of the developing murine genitourinary tract, Gene Expr. Patterns, 7, 680, 10.1016/j.modgep.2007.03.002

Mugford, 2008, Osr1 expression demarcates a multi-potent population of intermediate mesoderm that undergoes progressive restriction to an Osr1-dependent nephron progenitor compartment within the mammalian kidney, Dev. Biol., 324, 88, 10.1016/j.ydbio.2008.09.010

Mugford, 2009, High-resolution gene expression analysis of the developing mouse kidney defines novel cellular compartments within the nephron progenitor population, Dev. Biol., 333, 312, 10.1016/j.ydbio.2009.06.043

Park, 2007, Wnt/beta-catenin signaling regulates nephron induction during mouse kidney development, Development, 134, 2533, 10.1242/dev.006155

Park, 2012, Six2 and Wnt regulate self-renewal and commitment of nephron progenitors through shared gene regulatory networks, Dev. Cell, 23, 637, 10.1016/j.devcel.2012.07.008

Quaggin, 2008, Development of the renal glomerulus: good neighbors and good fences, Development, 135, 609, 10.1242/dev.001081

Saxen, 1987

Schedl, 2007, Renal abnormalities and their developmental origin, Nat. Rev. Genet., 8, 791, 10.1038/nrg2205

Shakya, 2005, The role of GDNF/Ret signaling in ureteric bud cell fate and branching morphogenesis, Dev. Cell, 8, 65, 10.1016/j.devcel.2004.11.008

Soriano, 1999, Generalized lacZ expression with the ROSA26 Cre reporter strain, Nat. Genet., 21, 70, 10.1038/5007

Visel, 2004, GenePaint.org: an atlas of gene expression patterns in the mouse embryo, Nucleic Acids Res., 32, D552, 10.1093/nar/gkh029

Wang, 2009, Cre/lox recombination in the lower urinary tract, Genesis, 47, 409, 10.1002/dvg.20515

Wiggins, 2007, The spectrum of podocytopathies: a unifying view of glomerular diseases, Kidney Int., 71, 1205, 10.1038/sj.ki.5002222

Yu, 2009, A Wnt7b-dependent pathway regulates the orientation of epithelial cell division and establishes the cortico-medullary axis of the mammalian kidney, Development, 136, 161, 10.1242/dev.022087

Zhang, 1997, Altered cell differentiation and proliferation in mice lacking p57KIP2 indicates a role in Beckwith-Wiedemann syndrome, Nature, 387, 151, 10.1038/387151a0