Identification of a CpG Island Methylator Phenotype that Defines a Distinct Subgroup of Glioma

Cancer Cell - Tập 17 Số 5 - Trang 510-522 - 2010
Houtan Noushmehr1, Daniel J. Weisenberger1, Kristin Alfaro-Munoz2, Heidi Phillips3, Kanan Pujara3, Benjamin P. Berman1, Fei Pan1, Christopher E. Pelloski4, Erik P. Sulman4, Krishna Bhat2, Roel G.W. Verhaak5,6, Katherine A. Hoadley7,8, D. Neil Hayes7,8, Charles M. Perou7,8, Heather K. Schmidt9, Li Ding9, Richard K. Wilson9, David D.L. Bowtell1, Hui Shen1, Henrik Bengtsson10, Pierre Neuvial10, Leslie Cope11, Jonathan D. Buckley12,1, James G. Herman11, Stephen B. Baylin11, Peter W. Laird1, Kenneth Aldape2
1USC Epigenome Center, University of Southern California, Los Angeles, CA 90033, USA
2Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
3Department of Tumor Biology and Angiogenesis, Genentech, Inc., South San Francisco, CA 94080, USA
4Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
5Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115 USA
6The Eli and Edythe L. Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142, USA
7Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
8Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
9The Genome Center at Washington University, Department of Genetics, Washington University School of Medicine, St. Louis, MI 63108, USA
10Department of Statistics, University of California, Berkeley, CA 94720, USA
11Department on Oncology, Johns Hopkins School of Medicine, Baltimore, MD 21231, USA
12Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA

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Cancer Cell

Tập 17 Số 5

510-522

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