Identification and experimental validation of druggable epigenetic targets in hepatoblastoma

Journal of Hepatology - Tập 79 - Trang 989-1005 - 2023
Alex Clavería-Cabello1, Jose Maria Herranz1,2, Maria Ujue Latasa1,2, Maria Arechederra1,2,3, Iker Uriarte1,2, Antonio Pineda-Lucena4, Felipe Prosper3,5, Pedro Berraondo6,7, Cristina Alonso8, Bruno Sangro2,3,9, Jose Juan García Marin2,10, Maria Luz Martinez-Chantar2,11, Sergio Ciordia12, Fernando José Corrales2,12, Paola Francalanci13, Rita Alaggio14, Jessica Zucman-Rossi15, Emilie Indersie16, Stefano Cairo16,17, Montserrat Domingo-Sàbat18
1Hepatology Program, CIMA, CCUN, University of Navarra, Pamplona, Spain
2CIBERehd, Instituto de Salud Carlos III, Madrid, Spain
3Instituto de Investigaciones Sanitarias de Navarra IdiSNA, Pamplona, Spain
4Molecular Therapeutics Program, CIMA, CCUN, University of Navarra, Pamplona, Spain
5Oncohematology Program, CIMA, CCUN, University of Navarra, Pamplona, Spain
6Immunology and Immunotherapy Program, CIMA, University of Navarra, Pamplona, Spain
7CIBERONC, Madrid, Spain
8OWL Metabolomics, Derio, Spain
9Hepatology Unit, CCUN, Navarra University Clinic, Pamplona, Spain
10Experimental Hepatology and Drug Targeting (HEVEFARM), University of Salamanca, IBSAL, Salamanca, Spain
11Liver Disease Laboratory, Center for Cooperative Research in Biosciences (CICbioGUNE), Basque Research and Technology Alliance (BRTA), Derio, Spain
12Functional Proteomics Laboratory, CNB-CSIC, Madrid, Spain
13Pathology Unit, Children's Hospital Bambino Gesù, IRCCS, Rome, Italy
14Pathology Unit, Children's Hospital Bambino Gesù, IRCCS, Sapienza University, Rome, Italy
15Centre de Recherche des Cordeliers, Sorbonne Université, Université de Paris, INSERM, Hôpital Européen Georges Pompidou, Paris, France
16XenTech, Evry-Courcouronnes, France
17Champions Oncology, Rockville, MD, USA
18Childhood Liver Oncology Group, Program of Predictive and Personalized Medicine of Cancer (PMPCC), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain

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