Identification and binding mode of a novel Leishmania Trypanothione reductase inhibitor from high throughput screening

PLOS Neglected Tropical Diseases - Tập 12 Số 11 - Trang e0006969
Lorenzo Turcano1, Esther Torrente1, Antonino Missineo1, Matteo Andreini1, Marina Gramiccia2, Trentina Di Muccio2, Ilaria Genovese3, Annarita Fiorillo3, Steven J. Harper1, Alberto Bresciani1, Gianni Colotti4, Andrea Ilari4
1IRBM Science Park S.p.A. Via Pontina Km 30,600–00071 Pomezia (RM), Italy
2Dipartimento di Malattie Infettive,—Istituto Superiore di Sanità Viale Regina Elena, Roma, Italy
3Dipartimento di Scienze Biochimiche, “Sapienza” Università di Roma P.le A. Moro, Roma, Italy
4Istituto di Biologia e Patologia Molecolari–CNR, and Dipartimento di Scienze Biochimiche, “Sapienza” Università di Roma P.le A. Moro, Roma, Italy

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