Identification and Characterization of Thymic Epithelial Progenitor Cells

Anderson, 2001, Lymphostromal interactions in thymus development and function, Nature Rev. Immunol., 1, 31, 10.1038/35095500 Anderson, 1993, MHC class II positive epithelium and mesenchyme cells are both required for T-cell development in the thymus, Nature, 362, 70, 10.1038/362070a0 Anderson, 1996, Cellular interactions in thymocyte development, Annu. Rev. Immunol., 14, 73, 10.1146/annurev.immunol.14.1.73 Anderson, 2000, Thymic vasculature, Int. Immunol., 12, 1105, 10.1093/intimm/12.7.1105 Auerbach, 1960, Morphogenetic interactions in the development of the mouse thymus gland, Dev. Biol., 2, 271, 10.1016/0012-1606(60)90009-9 Blackburn, 1996, The nu gene acts cell-autonomously and is required for differentiation of thymic epithelial progenitors, Proc. Natl. Acad. Sci. USA, 93, 5742, 10.1073/pnas.93.12.5742 Boyd, 1993, The thymic microenvironment, Immunol. Today, 14, 445, 10.1016/0167-5699(93)90248-J Chou, 1990, A rapid method to determine proliferation patterns of normal and malignant tissues by H3 mRNA in situ hybridization, Am. J. Pathol., 136, 729 Cordier, 1975, Nude mouse embryo, Scand. J. Immunol., 4, 193, 10.1111/j.1365-3083.1975.tb02616.x Cordier, 1980, Development of thymus, parathyroids, and ultimo-branchial bodies in NMRI and nude mice, Am. J. Anat., 157, 227, 10.1002/aja.1001570303 DeKoning, 1997, Thymic cortical epithelium is sufficient for the development of mature T cells in relB-deficient mice, J. Immunol., 158, 2558, 10.4049/jimmunol.158.6.2558 Fairchild, 2000, Extrathymic signals regulate the onset of T cell repertoire selection, Eur. J. Immunol., 30, 1948, 10.1002/1521-4141(200007)30:7<1948::AID-IMMU1948>3.0.CO;2-3 Ge, 2000, Effect of murine thymic epithelial cell line (MTEC1) on the functional expression of CD4+CD8- thymocytes subgroups, Int. Immunol., 12, 1127, 10.1093/intimm/12.8.1127 Godfrey, 1990, The phenotypic heterogeneity of mouse thymic stromal cells, Immunol. Today, 70, 66 Gordon, 2001, Gcm2 and Foxn1 mark early parathyroid- and thymus-specific domains in the developing third pharyngeal pouch, Mech. Dev., 103, 141, 10.1016/S0925-4773(01)00333-1 Haynes, 1984, Phenotypic characterization and ontogeny of mesodermal derived and endocrine components of the human thymic microenvironment, J. Exp. Med., 159, 1149, 10.1084/jem.159.4.1149 Hoffmann, 1992, Tolerance induction by thymic medullary epithelium, Proc. Natl. Acad. Sci. USA, 89, 2526, 10.1073/pnas.89.7.2526 Imami, 1992, A novel adhesion molecule in the murine thymic microenvironment, Dev. Immunol., 2, 161, 10.1155/1992/18016 Itoi, 2001, Two distinct steps of immigration of haematopoietic progenitors into the early thymus anlage, Int. Immunol., 13, 1203, 10.1093/intimm/13.9.1203 Janeway, 1996 Jotereau, 1987, Cell kinetics in the fetal mouse thymus, J. Immunol., 138, 1026, 10.4049/jimmunol.138.4.1026 Kaestner, 2000, Unified nomenclature for the winged helix/forkhead transcription factors, Genes Dev., 14, 142, 10.1101/gad.14.2.142 Klug, 1998, Interdependence of cortical thymic epithelial cell differentiation and T-lineage commitment, Proc. Natl. Acad. Sci. USA, 95, 11822, 10.1073/pnas.95.20.11822 Lampert, 1988, The origin of the diverse epithelial cells of the thymus Le Douarin, 1975, Tracing of cells of the avian thymus through embryonic life in interspecific chimeras, J. Exp. Med., 142, 17, 10.1084/jem.142.1.17 Lind, 2001, Mapping precursor movement through the postnatal thymus reveals specific microenvironments supporting defined stages of early lymphoid development, J. Exp. Med., 194, 127, 10.1084/jem.194.2.127 Manley, 2000, Thymus organogenesis and molecular mechanisms of thymic epithelial cell differentiation, Semin. Immunol., 12, 421, 10.1006/smim.2000.0263 Markert, 1999, Transplantation of thymus tissue in complete DiGeorge Syndrome, N. Engl. J. Med., 341, 1180, 10.1056/NEJM199910143411603 Matsuzaki, 1993, Characterization of c-kit positive intrathymic stem cells that are restricted to lymphoid differentiation, J. Exp. Med., 178, 1283, 10.1084/jem.178.4.1283 Miller, 1961, Immunological function of the thymus, Lancet, 2, 748, 10.1016/S0140-6736(61)90693-6 Nehls, 1994, New member of the winged-helix protein family disrupted in mouse and rat nude mutations, Nature, 372, 103, 10.1038/372103a0 Nehls, 1996, Two genetically separable steps in the differentiation of thymic epithelium, Science, 272, 886, 10.1126/science.272.5263.886 Owen, 1969, Tissue interaction in the development of thymus lymphocytes, J. Exp. Med., 129, 431, 10.1084/jem.129.2.431 Parham, 2000 Ritter, 1993, Development in the thymus, Immunol. Today, 14, 462, 10.1016/0167-5699(93)90250-O Rodewald, 2001, Thymus medulla consisting of epithelial islets each derived from a single progenitor, Nature, 414, 763, 10.1038/414763a Ropke, 1995, A common stem cell for murine cortical and medullary thymic epithelial cells?, Dev. Immunol., 4, 149, 10.1155/1995/23168 Schleup, 1988, Myasthenia gravis thymus, J Autoimmunity, 1, 445, 10.1016/0896-8411(88)90067-4 Smith, 1965, Studies on the thymus of the mammal. XIV. Histology and histochemistry of embryonic and early postnatal thymuses of C57BL/6 and AKR strain mice, Am. J. Anat., 116, 611, 10.1002/aja.1001160307 Tucek, 1990, Surface expression of CD4 and Thy-1 on mouse thymic stromal cells, Int. Immunol., 2, 593, 10.1093/intimm/2.7.593 Van Ewijk, 1982, Detection of Thy-1, T-200, Lyt-1 and Lyt-2-bearing cells in the developing lymphoid organs of the mouse embryo in vivo and in vitro, Eur. J. Immunol., 12, 262, 10.1002/eji.1830120403 Van Ewijk, 1999, Thymic microenvironments, 3-D versus 2-D?, Semin. Immunol., 11, 57, 10.1006/smim.1998.0158