Ibrutinib as initial therapy for elderly patients with chronic lymphocytic leukaemia or small lymphocytic lymphoma: an open-label, multicentre, phase 1b/2 trial

The Lancet Oncology - Tập 15 Số 1 - Trang 48-58 - 2014
Susan O’Brien1, Richard R. Furman2, Steven Coutré3, Jeff P. Sharman4, Jan A. Burger1, Kristie A. Blum5, Barbara Grant6, Donald Richards7, Morton Coleman2, William G. Wierda1, Jeffrey A. Jones5, Weiqiang Zhao8, Nyla A. Heerema8, Amy J. Johnson5, Raquel Izumi9, Ahmed Hamdy9, Betty Chang9, Thorsten Graef9, Fong Clow9, Joseph J. Buggy9, Danelle F. James9, John C. Byrd5
1Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
2Department of Medicine, Division of Hematology-Oncology, Weill Cornell Medical College, New York, NY, USA
3Division of Hematology and Stanford Cancer Center, Stanford University School of Medicine, Stanford, CA, USA.
4Willamette Valley Cancer Institute and Research Center/US Oncology Research, Springfield, OR, USA.
5Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA
6Vermont Cancer Center, University of Vermont, VT, USA
7Texas Oncology, US Oncology Research, Tyler, TX, USA
8Department of Pathology, The Ohio State University, Columbus, OH, USA
9Pharmacyclics, Sunnyvale, CA, USA

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