IL-33: an alarmin cytokine with crucial roles in innate immunity, inflammation and allergy

Current Opinion in Immunology - Tập 31 - Trang 31-37 - 2014
Corinne Cayrol1,2, Jean‐Philippe Girard1,2
1CNRS, IPBS (Institut de Pharmacologie et de Biologie Structurale), 205 route de Narbonne, F-31077 Toulouse, France
2Université de Toulouse; UPS; IPBS; F-31077 Toulouse, France

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Baekkevold, 2003, Molecular characterization of NF-HEV, a nuclear factor preferentially expressed in human high endothelial venules, Am J Pathol, 163, 69, 10.1016/S0002-9440(10)63631-0

Carriere, 2007, IL-33, the IL-1-like cytokine ligand for ST2 receptor, is a chromatin-associated nuclear factor in vivo, Proc Natl Acad Sci U S A, 104, 282, 10.1073/pnas.0606854104

Schmitz, 2005, IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines, Immunity, 23, 479, 10.1016/j.immuni.2005.09.015

Liu, 2013, Structural insights into the interaction of IL-33 with its receptors, Proc Natl Acad Sci U S A, 110, 14918, 10.1073/pnas.1308651110

Liew, 2010, Disease-associated functions of IL-33: the new kid in the IL-1 family, Nat Rev Immunol, 10, 103, 10.1038/nri2692

Garlanda, 2013, The interleukin-1 family: back to the future, Immunity, 39, 1003, 10.1016/j.immuni.2013.11.010

Moro, 2010, Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cells, Nature, 463, 540, 10.1038/nature08636

Neill, 2010, Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity, Nature, 464, 1367, 10.1038/nature08900

Price, 2010, Systemically dispersed innate IL-13-expressing cells in type 2 immunity, Proc Natl Acad Sci U S A, 107, 11489, 10.1073/pnas.1003988107

Mjosberg, 2011, Human IL-25- and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161, Nat Immunol, 12, 1055, 10.1038/ni.2104

Walker, 2013, Development and function of group 2 innate lymphoid cells, Curr Opin Immunol, 25, 148, 10.1016/j.coi.2013.02.010

Kim, 2013, Innate lymphoid cells and allergic inflammation, Curr Opin Immunol, 25, 738, 10.1016/j.coi.2013.07.013

Nussbaum, 2013, Type 2 innate lymphoid cells control eosinophil homeostasis, Nature, 502, 245, 10.1038/nature12526

Hung, 2013, IL-33 drives biphasic IL-13 production for noncanonical Type 2 immunity against hookworms, Proc Natl Acad Sci U S A, 110, 282, 10.1073/pnas.1206587110

Spooner, 2013, Specification of type 2 innate lymphocytes by the transcriptional determinant Gfi1, Nat Immunol, 14, 1229, 10.1038/ni.2743

Yasuda, 2012, Contribution of IL-33-activated type II innate lymphoid cells to pulmonary eosinophilia in intestinal nematode-infected mice, Proc Natl Acad Sci U S A, 109, 3451, 10.1073/pnas.1201042109

Van Dyken, 2014, Chitin activates parallel immune modules that direct distinct inflammatory responses via innate lymphoid type 2 and gammadelta T cells, Immunity, 40, 414, 10.1016/j.immuni.2014.02.003

Monticelli, 2011, Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus, Nat Immunol, 12, 1045, 10.1038/ni.2131

Chang, 2011, Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity, Nat Immunol, 12, 631, 10.1038/ni.2045

Byers, 2013, Long-term IL-33-producing epithelial progenitor cells in chronic obstructive lung disease, J Clin Invest, 123, 3967, 10.1172/JCI65570

Bonilla, 2012, The alarmin interleukin-33 drives protective antiviral CD8 T cell responses, Science, 335, 984, 10.1126/science.1215418

Oboki, 2010, IL-33 is a crucial amplifier of innate rather than acquired immunity, Proc Natl Acad Sci U S A, 107, 18581, 10.1073/pnas.1003059107

Louten, 2011, Endogenous IL-33 enhances Th2 cytokine production and T-cell responses during allergic airway inflammation, Int Immunol, 23, 307, 10.1093/intimm/dxr006

Bartemes, 2012, IL-33-responsive lineage-CD25+CD44hi lymphoid cells mediate innate type 2 immunity and allergic inflammation in the lungs, J Immunol, 188, 1503, 10.4049/jimmunol.1102832

Barlow, 2013, IL-33 is more potent than IL-25 in provoking IL-13-producing nuocytes (type 2 innate lymphoid cells) and airway contraction, J Allergy Clin Immunol, 132, 933, 10.1016/j.jaci.2013.05.012

Kamijo, 2013, IL-33-mediated innate response and adaptive immune cells contribute to maximum responses of protease allergen-induced allergic airway inflammation, J Immunol, 190, 4489, 10.4049/jimmunol.1201212

Halim, 2014, Group 2 innate lymphoid cells are critical for the initiation of adaptive T helper 2 cell-mediated allergic lung inflammation, Immunity, 40, 425, 10.1016/j.immuni.2014.01.011

Hara, 2014, Airway uric acid is a sensor of inhaled protease allergens and initiates type 2 immune responses in respiratory mucosa, J Immunol, 192, 4032, 10.4049/jimmunol.1400110

Haenuki, 2012, A critical role of IL-33 in experimental allergic rhinitis, J Allergy Clin Immunol, 130, 10.1016/j.jaci.2012.02.013

Salimi, 2013, A role for IL-25 and IL-33-driven type-2 innate lymphoid cells in atopic dermatitis, J Exp Med, 210, 2939, 10.1084/jem.20130351

Gudbjartsson, 2009, Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction, Nat Genet, 41, 342, 10.1038/ng.323

Moffatt, 2010, A large-scale, consortium-based genomewide association study of asthma, N Engl J Med, 363, 1211, 10.1056/NEJMoa0906312

Torgerson, 2011, Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations, Nat Genet, 43, 887, 10.1038/ng.888

Ramasamy, 2012, Genome-wide association studies of asthma in population-based cohorts confirm known and suggested loci and identify an additional association near HLA, PLoS ONE, 7, e44008, 10.1371/journal.pone.0044008

Bonnelykke, 2014, A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations, Nat Genet, 46, 51, 10.1038/ng.2830

Moussion, 2008, The IL-1-like cytokine IL-33 is constitutively expressed in the nucleus of endothelial cells and epithelial cells in vivo: a novel ‘alarmin’?, PLoS ONE, 3, e3331, 10.1371/journal.pone.0003331

Pichery, 2012, Endogenous IL-33 is highly expressed in mouse epithelial barrier tissues, lymphoid organs, brain, embryos, and inflamed tissues: in situ analysis using a novel IL-33-LacZ gene trap reporter strain, J Immunol, 188, 3488, 10.4049/jimmunol.1101977

Roussel, 2008, Molecular mimicry between IL-33 and KSHV for attachment to chromatin through the H2A–H2B acidic pocket, EMBO Rep, 9, 1006, 10.1038/embor.2008.145

Bessa, 2014, Altered subcellular localization of IL-33 leads to non-resolving lethal inflammation, J Autoimmun, 10.1016/j.jaut.2014.02.012

Hardman, 2013, IL-33 citrine reporter mice reveal the temporal and spatial expression of IL-33 during allergic lung inflammation, Eur J Immunol, 43, 488, 10.1002/eji.201242863

Prefontaine, 2010, Increased IL-33 expression by epithelial cells in bronchial asthma, J Allergy Clin Immunol, 125, 752, 10.1016/j.jaci.2009.12.935

Arshad, 2012, TRAIL but not FasL and TNFalpha, regulates IL-33 expression in murine hepatocytes during acute hepatitis, Hepatology, 56, 2353, 10.1002/hep.25893

Tjota, 2013, IL-33-dependent induction of allergic lung inflammation by FcgammaRIII signaling, J Clin Invest, 123, 2287, 10.1172/JCI63802

Nakanishi, 2013, IL-33, but Not IL-25, is crucial for the development of house dust mite antigen-induced allergic rhinitis, PLoS ONE, 8, e78099, 10.1371/journal.pone.0078099

Cayrol, 2009, The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1, Proc Natl Acad Sci U S A, 106, 9021, 10.1073/pnas.0812690106

Luthi, 2009, Suppression of interleukin-33 bioactivity through proteolysis by apoptotic caspases, Immunity, 31, 84, 10.1016/j.immuni.2009.05.007

Kouzaki, 2011, The danger signal, extracellular ATP, is a sensor for an airborne allergen and triggers IL-33 release and innate Th2-type responses, J Immunol, 186, 4375, 10.4049/jimmunol.1003020

Snelgrove, 2014, Alternaria-derived serine protease activity drives IL-33 mediated asthma exacerbations, J Allergy Clin Immunol, 134, 10.1016/j.jaci.2014.02.002

Lefrancais, 2012, IL-33 is processed into mature bioactive forms by neutrophil elastase and cathepsin G, Proc Natl Acad Sci U S A, 109, 1673, 10.1073/pnas.1115884109