Hydrophobicity/hydrophilicity descriptors obtained from extrapolated chromatographic retention data as modeling tools for biological distribution: Application to some oxime-type acetylcholinesterase reactivators

Journal of Pharmaceutical and Biomedical Analysis - Tập 52 - Trang 508-516 - 2010
Victor Voicu1,2, Iuliana Sora3, Costel Sârbu4, Victor David5, Andrei Medvedovici5,3
1University of Medicine and Pharmacy “Carol Davilla”, Department of Pharmacology, Toxicology and Clinical Psychopharmacology, #8 Floreasca Street, Bucharest 014461, Romania
2Romanian Army Center for Medical Research, # 37 C.A. Rosetti Street, Bucharest 020012, Romania
3Bioanalytical Laboratory, SC Labormed Pharma SA, #44B Th. Pallady Blvd., Bucharest 032266, Romania
4Babeş-Bolyai University, Faculty of Chemistry and Chemical Engineering, #11 Arany Janos Street, Cluj-Napoca 400028, Romania
5University of Bucharest, Faculty of Chemistry, Department of Analytical Chemistry, #90 Panduri Avenue, Bucharest 050663, Romania

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Journal of Pharmaceutical and Biomedical Analysis

Tập 52

508-516

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