Hydroimidazolone modification of human αA-crystallin: Effect on the chaperone function and protein refolding ability

Harding, 1991 Bloemendal, 1982, Lens proteins, CRC Crit. Rev. Biochem., 12, 1, 10.3109/10409238209105849 Ingolia, 1982, Four small Drosophila heat shock proteins are related to each other and to mammalian alpha-crystallin, Proc. Natl. Acad. Sci. U. S. A., 79, 2360, 10.1073/pnas.79.7.2360 Narberhaus, 2002, Alpha-crystallin-type heat shock proteins: socializing minichaperones in the context of a multichaperone network, Microbiol. Mol. Biol. Rev., 66, 64, 10.1128/MMBR.66.1.64-93.2002 Derham, 1999, Alpha-crystallin as a molecular chaperone, Prog. Retin. Eye Res., 18, 463, 10.1016/S1350-9462(98)00030-5 Horwitz, 2003, Alpha-crystallin, Exp. Eye Res., 76, 145, 10.1016/S0014-4835(02)00278-6 Horwitz, 2008, Alpha crystallin: the quest for a homogeneous quaternary structure, Exp. Eye Res. Horwitz, 2004, The native oligomeric organization of alpha-crystallin, is it necessary for its chaperone function?, Exp. Eye Res., 79, 817, 10.1016/j.exer.2004.05.007 Sharma, 2000, Synthesis and characterization of a peptide identified as a functional element in alphaA-crystallin, J. Biol. Chem., 275, 3767, 10.1074/jbc.275.6.3767 Brady, 1997, Targeted disruption of the mouse alpha A-crystallin gene induces cataract and cytoplasmic inclusion bodies containing the small heat shock protein alpha B-crystallin, Proc. Natl. Acad. Sci. U. S. A., 94, 884, 10.1073/pnas.94.3.884 Boyle, 2003, Morphological characterization of the Alpha A- and Alpha B-crystallin double knockout mouse lens, BMC Ophthalmol., 3, 3, 10.1186/1471-2415-3-3 Shroff, 2000, Mutation of R116C results in highly oligomerized alpha A-crystallin with modified structure and defective chaperone-like function, Biochemistry, 39, 1420, 10.1021/bi991656b Treweek, 2005, R120G alphaB-crystallin promotes the unfolding of reduced alpha-lactalbumin and is inherently unstable, FEBS J., 272, 711, 10.1111/j.1742-4658.2004.04507.x Xi, 2008, Mechanism of small heat shock protein function in vivo: a knock-in mouse model demonstrates that the R49C mutation in alpha A-crystallin enhances protein insolubility and cell death, J. Biol. Chem., 283, 5801, 10.1074/jbc.M708704200 Hsu, 2006, A transgenic mouse model for human autosomal dominant cataract, Invest. Ophthalmol. Vis. Sci., 47, 2036, 10.1167/iovs.05-0524 Cherian, 1995, Decreased molecular chaperone property of alpha-crystallins due to posttranslational modifications, Biochem. Biophys. Res. Commun., 208, 675, 10.1006/bbrc.1995.1391 Thampi, 2002, Enhanced C-terminal truncation of alphaA- and alphaB-crystallins in diabetic lenses, Invest. Ophthalmol. Vis. Sci., 43, 3265 Thornalley, 1993, The glyoxalase system in health and disease, Mol. Aspects Med., 14, 287, 10.1016/0098-2997(93)90002-U Ahmed, 1997, N-epsilon-(carboxyethyl)lysine, a product of the chemical modification of proteins by methylglyoxal, increases with age in human lens proteins, Biochem. J., 324, 565, 10.1042/bj3240565 Chellan, 1999, Protein crosslinking by the Maillard reaction: dicarbonyl-derived imidazolium crosslinks in aging and diabetes, Arch. Biochem. Biophys., 368, 98, 10.1006/abbi.1999.1291 Biemel, 2002, Identification and quantification of major maillard cross-links in human serum albumin and lens protein. Evidence for glucosepane as the dominant compound, J. Biol. Chem., 277, 24907, 10.1074/jbc.M202681200 Ahmed, 2003, Methylglyoxal-derived hydroimidazolone advanced glycation end-products of human lens proteins, Invest. Ophthalmol. Vis. Sci., 44, 5287, 10.1167/iovs.03-0573 Wilker, 2001, Chromatographic quantification of argpyrimidine, a methylglyoxal-derived product in tissue proteins: comparison with pentosidine, Anal. Biochem., 290, 353, 10.1006/abio.2001.4992 Kumar, 2004, Effect of dicarbonyl-induced browning on alpha-crystallin chaperone-like activity: physiological significance and caveats of in vitro aggregation assays, Biochem. J., 379, 273, 10.1042/bj20031633 Nagaraj, 2003, Enhancement of chaperone function of alpha-crystallin by methylglyoxal modification, Biochemistry, 42, 10746, 10.1021/bi034541n Biswas, 2006, Effect of site-directed mutagenesis of methylglyoxal-modifiable arginine residues on the structure and chaperone function of human alphaA-crystallin, Biochemistry, 45, 4569, 10.1021/bi052574s Biswas, 2008, Chemical modulation of the chaperone function of human {alpha}A-crystallin, J. Biochem., 144, 21, 10.1093/jb/mvn037 Ahmed, 2005, Peptide mapping identifies hotspot site of modification in human serum albumin by methylglyoxal involved in ligand binding and esterase activity, J. Biol. Chem., 280, 5724, 10.1074/jbc.M410973200 Ahmed, 2002, Chromatographic assay of glycation adducts in human serum albumin glycated in vitro by derivatization with 6-aminoquinolyl-N-hydroxysuccinimidyl-carbamate and intrinsic fluorescence, Biochem. J., 364, 15, 10.1042/bj3640015 Biswas, 2007, Alpha-crystallin assisted refolding of enzyme substrates: optimization of external parameters, Protein J., 26, 247, 10.1007/s10930-006-9066-8 Biswas, 2008, Zn2+ enhances the molecular chaperone function and stability of alpha-crystallin, Biochemistry, 47, 804, 10.1021/bi7011965 Kumar, 2005, Alphab-crystallin-assisted reactivation of glucose-6-phosphate dehydrogenase upon refolding, Biochem. J., 391, 335, 10.1093/jb/mvi131 Henle, 1994, Detection and identification of a protein-bound imidazolone resulting from the reaction of arginine residues and methylglyoxal, Z. Lebensm. Unters. Forsch., 199, 55, 10.1007/BF01192954 Ahmed, 2002, Biochem. J., 364, 1, 10.1042/bj3640001 Santhoshkumar, 2001, Phe71 is essential for chaperone-like function in alpha A-crystallin, J. Biol. Chem., 276, 47094, 10.1074/jbc.M107737200 Derham, 1997, Effect of aging on the chaperone-like function of human alpha-crystallin assessed by three methods, Biochem. J., 328, 763, 10.1042/bj3280763 Bhattacharyya, 1998, Alpha-crystallin does not require temperature activation for its chaperone-like activity, Biochem. Mol. Biol. Int., 46, 249 Zhi, 1992, Renaturation of citrate synthase: influence of denaturant and folding assistants, Protein Sci., 1, 522, 10.1002/pro.5560010407 Raman, 1995, Rapid refolding studies on the chaperone-like alpha-crystallin. Effect of alpha-crystallin on refolding of beta- and gamma-crystallins, J. Biol. Chem., 270, 19888, 10.1074/jbc.270.34.19888 Ahmed, 2005, Peptide mapping of human serum albumin modified minimally by methylglyoxal in vitro and in vivo, Ann. N. Y. Acad. Sci., 1043, 260, 10.1196/annals.1333.031 Haik, 1994, Methylglyoxal concentration and glyoxalase activities in the human lens, Exp. Eye Res., 59, 497, 10.1006/exer.1994.1135 McClure, 1966, Fluorescent probes for conformational states of proteins. I. Mechanism of fluorescence of 2-p-toluidinylnaphthalene-6-sulfonate, a hydrophobic probe, Biochemistry, 5, 1908, 10.1021/bi00870a018 Bera, 2002, A positive charge preservation at position 116 of alpha A-crystallin is critical for its structural and functional integrity, Biochemistry, 41, 12421, 10.1021/bi0204140 Shroff, 2001, Substituted hydrophobic and hydrophilic residues at methionine-68 influence the chaperone-like function of alphaB-crystallin, Mol. Cell. Biochem., 220, 127, 10.1023/A:1010834107809 Reddy, 2006, Chaperone-like activity and hydrophobicity of alpha-crystallin, IUBMB Life, 58, 632, 10.1080/15216540601010096 Khanova, 2007, Effect of alpha-crystallin on thermal denaturation and aggregation of rabbit muscle glyceraldehyde-3-phosphate dehydrogenase, Biophys. Chem., 125, 521, 10.1016/j.bpc.2006.11.002 Rajaraman, 1996, Molten-globule state of carbonic anhydrase binds to the chaperone-like alpha-crystallin, J. Biol. Chem., 271, 27595, 10.1074/jbc.271.44.27595 Hess, 1998, Protection of a restriction enzyme from heat inactivation by [alpha]-crystallin, Mol. Vis., 4, 29 Rajaraman, 2001, Interaction of human recombinant alphaA- and alphaB-crystallins with early and late unfolding intermediates of citrate synthase on its thermal denaturation, FEBS Lett., 497, 118, 10.1016/S0014-5793(01)02451-6 Raman, 1997, Effect of the chaperone-like alpha-crystallin on the refolding of lysozyme and ribonuclease A, FEBS Lett., 416, 369, 10.1016/S0014-5793(97)01240-4 Ganea, 2000, alpha-crystallin assists the renaturation of glyceraldehyde-3-phosphate dehydrogenase, Biochem. J., 345, 467, 10.1042/0264-6021:3450467 Benesch, 2008, Small heat shock protein activity is regulated by variable oligomeric substructure, J. Biol. Chem., 283, 28513, 10.1074/jbc.M804729200