Hydrogen peroxide causes dimethylthiourea consumption while hydroxyl radical causes dimethyl sulfoxide consumption in vitro

McCord, 1978, The biology and pathology of oxygen radicals, Ann. Int. Med., 89, 122, 10.7326/0003-4819-89-1-122 McCord, 1985, Oxygen-derived free radicals in post ischemic tissue injury, New Engl. J. Med., 312, 159, 10.1056/NEJM198501173120305 Turrens, 1984, Protection against oxygen toxicity by intravenous injection of liposome entrapped catalase and superoxide dismutase, J. Clin. Invest., 73, 879, 10.1172/JCI111210 Tate, 1982, Oxygen radical mediated permeability edema and vasoconstriction in isolated perfused rabbit lungs, Am. Rev. Respir. Dis., 126, 802 Harada, 1983, Oxygen radical scavengers protect alveolar macrophages from hyperoxic injury in vitro, Am. Rev. Respir. Dis., 128, 761 Fox, 1983, Prevention of thiourea-induced pulmonary edema by hydroxyl radical scavengers, J. Appl. Physiol., 55, 1456, 10.1152/jappl.1983.55.5.1456 Jackson, 1983, Dimethylthiourea (DMTU), an O2 radical scavenger, prevents acute edematous lung injury (ARDS) following injection for phorbol myristate acetate (PMA), Clin. Res., 31, 96A Fox, 1984, Prevention of granulocyte-mediated oxidant injury in rats by a hydroxyl radical scavenger, dimethylthiourea, J. Clin. Invest., 74, 1456, 10.1172/JCI111558 Antony, 1984, Dimethylthiourea prevents oxygen radical mediated pleural fibrosis in experimental pleurisy, Clin. Res., 32, 424A Repine, 1981, Dimethyl sulfoxide prevents DNA nicking mediated by ionizing radiation or iron/hydrogen peroxide generated hydroxyl radical, 78, 1001 Linas, 1985, Dimethylthiourea (DMTU) prevents hydrogen (H2O2)-mediated injury and is consumed by H2O2 in the isolated perfused kidney, Clin. Res., 33, 491A Toth, 1984, Intact human erythrocytes prevent hydrogen peroxide mediated damage to endothelial cells and corresponding disappearance of dimethylthiourea, Clin. Res., 32, 88A Jackson, 1985, Dimethylthiourea consumption reflects hydrogen peroxide concentrations and the severity of acute edematous lung injury, J. Appl. Physiol., 59, 1995, 10.1152/jappl.1985.59.6.1995 Langleben, 1985, Effect of dimethylthiourea on hypoxia-induced right ventricular hypertrophy, Clin. Res., 33, 78A Garretson, 1982, Determination of dimethyl sulfoxide in serum and other body fluids by gas chromatography, J. Anal. Toxic., 6, 76, 10.1093/jat/6.2.76 Toth, 1984, Intact human erythrocytes prevent hydrogen peroxide mediated damage to isolated perfused rat lungs and cultured bovine pulmonary artery endothelial cells, J. Clin. Invest., 74, 292, 10.1172/JCI111414 Mccord, 1978, Superoxide-dependent production of hydroxyl radical catalyzed by iron-EDTA complex, FEBS Lett., 86, 139, 10.1016/0014-5793(78)80116-1 Repine, 1981, Hydrogen peroxide kills Staphylococcus aureus by reacting with staphylococcal iron to form hydroxyl radical, J. Biol. Chem., 256, 7094, 10.1016/S0021-9258(19)68927-1 Repine, 1979, Generation of hydroxyl radicals by enzymes, chemicals and human phagocytes in vitro, J. Clin. Invest., 64, 1642, 10.1172/JCI109626 Veltwisch, 1980, Primary processes in the reaction of ·OH radicals with sulfoxides, J. Chem. Soc. Pekin, II, 146 Cederbaum, 1979, Effect of thiourea on microsomal oxidation of alcohols and associated microsomal function, Biochem., 18, 1187, 10.1021/bi00574a011 Klein, 1981, Production of formaldehyde during metabolism of dimethyl sulfoxide by hydroxyl radical generating systems, Biochem., 20, 6006, 10.1021/bi00524a013 Kobayashi, 1981, Simultaneous quantitation of thiourea in rat plasma by high-performance liquid chromatography, J. Chromatogr., 207, 281, 10.1016/S0021-9673(00)89945-8