Hybrid Modelling and Process Optimization of Biological Systems

3rd International Workshop on Equation-Based Object-Oriented Modeling Languages and Tools. Conference proceedings, 63–70. Braun W, Ochel L, Bachmann B (2011) Symbolically Derived Jacobians Using Automatic Differentiation -Enhancement of the OpenModelica Compiler. Modelica Conference proceedings. Chelouah, 2003, Genetic and Nelder-Mead algorithms hybridized for a more accurate global optimization of continuous multiminima functions, European Journal of Operational Research, 148, 335, 10.1016/S0377-2217(02)00401-0 David R, Alla H (2001) On Hybrid Petri Nets. Discrete Event Dynamic Systems: Theory and Applications (11), 9–40. AB, 2010, Dymola-Dynamic Modeling Laboratory-User Manual, 2 Hooke, 1961, Direct Search Solution of Numerical and Statistical Problems, Journal of the ACM, 8, 212, 10.1145/321062.321069 Modelica Association (2010) Modelica - A Unified Object-Oriented Language for Physical Systems Modeling. Language Specification Version 3.2. Proß S, Bachmann B (2009) A Petri Net Library for Modeling Hybrid Systems in OpenModelica. Modelica Conference proceedings. Proß S, Bachmann B (2011a) An Advanced Environment for Hybrid Modeling of Biological Systems Based on Modelica. Journal of Integrative Bioinformatics (8), 1–34. Proß S, Bachmann B (2011b) An Advanced Environment for Hybrid Modeling and Parameter Identification of Biological Systems. Modelica Conference proceedings. Proß S, Bachmann B, Hofestädt R, Niehaus K, Ueckerdt R, Vorhölter FJ, Lutter P (2009) Modeling a Bacterium's Life: A Petri-Net Library in Modelica. Modelica Conference proceedings. Rechenberg I (1971) Evolutionsstrategie: Optimierung technischer Systeme nach Prinzipien der biologischen Evolution. Dr.-Ing. Thesis, Technical University of Berlin. Schwefel H (1975) Evolutionsstrategie und numerische Optimierung. Dissertation, TU Berlin. Wiechert, 2002, Modeling and simulation: tools for metabolic engineering, Journal of biotechnology, 94, 37, 10.1016/S0168-1656(01)00418-7