Humoral Fingerprinting of Immune Responses: ‘Super-Resolution’, High-Dimensional Serology

Trends in Immunology - Tập 37 - Trang 167-169 - 2016
William W. Lau1, John S. Tsang2
1Office of Intramural Research, Center for Information Technology, National Institutes of Health, Bethesda, MD, USA
2Systems Genomics and Bioinformatics Unit, Laboratory of Systems Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA

Tài liệu tham khảo

Tsang, 2015, Utilizing population variation, vaccination, and systems biology to study human immunology, Trends Immunol., 36, 479, 10.1016/j.it.2015.06.005 Chung, 2015, Dissecting polyclonal vaccine-induced humoral immunity against HIV using systems serology, Cell, 163, 988, 10.1016/j.cell.2015.10.027 Plotkin, 2008, Correlates of vaccine-induced immunity, Clin. Infect. Dis., 47, 401, 10.1086/589862 Takai, 2002, Roles of Fc receptors in autoimmunity, Nat. Rev. Immunol., 2, 580, 10.1038/nri856 Ideker, 2012, Differential network biology, Mol. Syst. Biol., 8, 565, 10.1038/msb.2011.99 de la Fuente, 2010, From ‘differential expression’ to ‘differential networking’ – identification of dysfunctional regulatory networks in diseases, Trends Genet., 26, 326, 10.1016/j.tig.2010.05.001 Tsang, 2014, Global analyses of human immune variation reveal baseline predictors of postvaccination responses, Cell, 157, 499, 10.1016/j.cell.2014.03.031 Furman, 2013, Apoptosis and other immune biomarkers predict influenza vaccine responsiveness, Mol. Syst. Biol., 9, 659, 10.1038/msb.2013.15 Robinson, 2015, Sequencing the functional antibody repertoire – diagnostic and therapeutic discovery, Nat. Rev. Rheumatol., 11, 171, 10.1038/nrrheum.2014.220