Human umbilical cord blood-derived stromal cells prevent graft-versus-host disease in mice following haplo-identical stem cell transplantation

Cytotherapy - Tập 13 - Trang 83-91 - 2011
Lei Hao1, Lei Gao1, Xing-Hua Chen1, Zhong-Min Zou2, Xi Zhang1, Pei-Yan Kong1, Cheng Zhang1, Xian-Gui Peng1, Ai-Hua Sun1, Qing-Yu Wang1
1Department of Hematology, Xinqiao Hospital
2Department of Chemical Defense and Toxicology, Third Military Medical University, Chongqing, China

Tài liệu tham khảo

Beatty, 1991, Marrow transplantation from HLA-matched unrelated donors for treatment of hematologic malignancies, Transplantation, 51, 443, 10.1097/00007890-199102000-00034 Martin, 1987, Human marrow transplantation: an immunological perspective, Adv Immunol, 40, 379, 10.1016/S0065-2776(08)60243-6 Ikehara, 2003, A new concept of stem cell disorders and their new therapy, J Hematother Stem Cell Res, 12, 643, 10.1089/15258160360732678 Sun, 2007, Pathophysiology of acute graft-versus-host disease: recent advances, Transl Res, 150, 197, 10.1016/j.trsl.2007.06.003 Nash, 2000, Phase 3 study comparing methotrexate and tacrolimus with methotrexate and cyclosporine for prophylaxis of acute graft-versus-host disease after marrow transplantation from unrelated donors, Blood, 96, 2062 Ratanatharathorn, 1998, Phase III study comparing methotrexate and tacrolimus (prograf, FK506) with methotrexate and cyclosporine for graft-versus-host disease prophylaxis after HLA-identical sibling bone marrow transplantation, Blood, 92, 2303 Zeiser, 2004, Immunopathogenesis of acute graft-versus-host disease: implications for novel preventive and therapeutic strategies, Ann Hematol, 83, 551, 10.1007/s00277-004-0890-7 Di Nicola, 2002, Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli, Blood, 99, 3838, 10.1182/blood.V99.10.3838 Tse, 2003, Suppression of allogeneic T-cell proliferation by human marrow stromal cells: implications in transplantation, Transplantation, 75, 389, 10.1097/01.TP.0000045055.63901.A9 Potian, 2003, Veto-like activity of mesenchymal stem cells: functional discrimination between cellular responses to alloantigens and recall antigens, J Immunol, 171, 3426, 10.4049/jimmunol.171.7.3426 Krampera, 2006, Role for interferon-gamma in the immunomodulatory activity of human bone marrow mesenchymal stem cells, Stem Cells, 24, 386, 10.1634/stemcells.2005-0008 Le Blanc, 2003, Immunomodulatory effects of fetal and adult mesenchymal stem cells, Cytotherapy, 5, 485, 10.1080/14653240310003611 Lazarus, 2005, Cotransplantation of HLA-identical sibling culture-expanded mesenchymal stem cells and hematopoietic stem cells in hematologic malignancy patients, Biol Blood Marrow Transplant, 11, 389, 10.1016/j.bbmt.2005.02.001 Min, 2007, IL-10-transduced bone marrow mesenchymal stem cells can attenuate the severity of acute graft-versus-host disease after experimental allogeneic stem cell transplantation, Bone Marrow Transplant, 39, 637, 10.1038/sj.bmt.1705644 Itakura, 2007, Mesenchymal stem cells facilitate the induction of mixed hematopoietic chimerism and islet allograft tolerance without GVHD in the rat, Am J Transplant, 7, 336, 10.1111/j.1600-6143.2006.01643.x Ringden, 2006, Mesenchymal stem cells for treatment of therapy-resistant graft-versus-host disease, Transplantation, 81, 1390, 10.1097/01.tp.0000214462.63943.14 Tisato, 2007, Mesenchymal stem cells of cord blood origin are effective at preventing but not treating graft-versus-host disease, Leukemia, 21, 1992, 10.1038/sj.leu.2404847 Gao, 2006, Human umbilical cord blood-derived stromal cell, a new resource of feeder layer to expand human umbilical cord blood CD34+ cells in vitro, Blood Cells Mol Dis, 36, 322, 10.1016/j.bcmd.2005.12.036 Hao, 2009, Human umbilical cord blood-derived stromal cells suppress xenogeneic immune cell response in vitro, Croat Med J, 50, 351, 10.3325/cmj.2009.50.351 Cooke, 1996, An experimental model of idiopathic pneumonia syndrome after bone marrow transplantation. I. The roles of minor H antigens and endotoxin, Blood, 88, 3230, 10.1182/blood.V88.8.3230.bloodjournal8883230 Ferrara, 1986, Cutaneous acute graft-versus-host disease to minor histocompatibility antigens in a murine model: histologic analysis and correlation to clinical disease, J Invest Dermatol, 86, 371, 10.1111/1523-1747.ep12285612 Grass, 1999, Prevention of transfusion-associated graft-versus-host disease by photochemical treatment, Blood, 93, 3140, 10.1182/blood.V93.9.3140 Hill, 1997, Total body irradiation and acute graft-versus-host disease: the role of gastrointestinal damage and inflammatory cytokines, Blood, 90, 3204, 10.1182/blood.V90.8.3204 Le Blanc, 2004, Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells, Lancet, 363, 1439, 10.1016/S0140-6736(04)16104-7 Le Blanc, 2008, Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study, Lancet, 371, 1579, 10.1016/S0140-6736(08)60690-X Wilson, 2009, Antibody to the dendritic cell surface activation antigen CD83 prevents acute graft-versus-host disease, J Exp Med, 206, 387, 10.1084/jem.20070723 Jiang, 2005, Human mesenchymal stem cells inhibit differentiation and function of monocyte-derived dendritic cells, Blood, 105, 4120, 10.1182/blood-2004-02-0586 Nauta, 2006, Mesenchymal stem cells inhibit generation and function of both CD34+-derived and monocyte-derived dendritic cells, J Immunol, 177, 2080, 10.4049/jimmunol.177.4.2080 Zhang, 2004, Effects of mesenchymal stem cells on differentiation, maturation, and function of human monocyte-derived dendritic cells, Stem Cells Dev, 13, 263, 10.1089/154732804323099190 Itoh, 1999, Thymus and autoimmunity: production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance, J Immunol, 162, 5317, 10.4049/jimmunol.162.9.5317 Stephens, 2000, CD25 is a marker for CD4+ thymocytes that prevent autoimmune diabetes in rats, but peripheral T cells with this function are found in both CD25+ and CD25− subpopulations, J Immunol, 165, 3105, 10.4049/jimmunol.165.6.3105 Stephens, 2001, Human CD4(+)CD25(+) thymocytes and peripheral T cells have immune suppressive activity in vitro, Eur J Immunol, 31, 1247, 10.1002/1521-4141(200104)31:4<1247::AID-IMMU1247>3.0.CO;2-M Shevach, 2001, Control of T-cell activation by CD4+ CD25+ suppressor T cells, Immunol Rev, 182, 58, 10.1034/j.1600-065X.2001.1820104.x Thornton, 1998, CD4+ CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production, J Exp Med, 188, 287, 10.1084/jem.188.2.287 Piccirillo, 2001, Cutting edge: control of CD8+ T cell activation by CD4+ CD25+ immunoregulatory cells, J Immunol, 167, 1137, 10.4049/jimmunol.167.3.1137 Annacker, 2000, Regulatory CD4 T cells control the size of the peripheral activated/memory CD4 T cell compartment, J Immunol, 164, 3573, 10.4049/jimmunol.164.7.3573 Hess, 1994, Characterization of peripheral autoregulatory mechanisms that prevent development of cyclosporin-induced syngeneic graft-versus-host disease, J Immunol, 153, 400, 10.4049/jimmunol.153.1.400 Taylor, 2001, CD4(+) CD25(+) immune regulatory cells are required for induction of tolerance to alloantigen via costimulatory blockade, J Exp Med, 193, 1311, 10.1084/jem.193.11.1311 Hoffmann, 2002, Donor-type CD4(+) CD25(+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation, J Exp Med, 196, 389, 10.1084/jem.20020399 Taylor, 2002, The infusion of ex vivo activated and expanded CD4(+) CD25(+) immune regulatory cells inhibits graft-versus-host disease lethality, Blood, 99, 3493, 10.1182/blood.V99.10.3493 Maccario, 2005, Interaction of human mesenchymal stem cells with cells involved in alloantigen-specific immune response favors the differentiation of CD4+ T-cell subsets expressing a regulatory/suppressive phenotype, Haematologica, 90, 516 Aggarwal, 2005, Human mesenchymal stem cells modulate allogeneic immune cell responses, Blood, 105, 1815, 10.1182/blood-2004-04-1559 Tian, 2008, Bone marrow-derived mesenchymal stem cells decrease acute graft-versus-host disease after allogeneic hematopoietic stem cells transplantation, Immunol Invest, 37, 29, 10.1080/08820130701410223 von Boehmer, 2005, Mechanisms of suppression by suppressor T cells, Nat Immunol, 6, 338, 10.1038/ni1180 Picca, 2005, The role of self-peptides in the development of CD4+ CD25+ regulatory T cells, Curr Opin Immunol, 17, 131, 10.1016/j.coi.2005.01.003 Sakaguchi, 2005, Naturally arising Foxp3-expressing CD25+ CD4+ regulatory T cells in immunological tolerance to self and non-self, Nat Immunol, 6, 345, 10.1038/ni1178 Kovacsovics-Bankowski, 2009, Clinical scale expanded adult pluripotent stem cells prevent graft-versus-host disease, Cell Immunol, 255, 55, 10.1016/j.cellimm.2008.10.004 Polchert, 2008, IFN-gamma activation of mesenchymal stem cells for treatment and prevention of graft versus host disease, Eur J Immunol, 38, 1745, 10.1002/eji.200738129