Human genetics, natriuretic peptides and hypertension

Christopher Newton‐Cheh1,2
1Massachusetts General Hospital, Boston, USA
2Broad Institute of Harvard and MIT, Cambridge, USA

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Tài liệu tham khảo

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Newton-Cheh C, Johnson T, Gateva V, Tobin MD, Bochud M, Coin L, Najjar SS: Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet. 2009, 41: 666-676. 10.1038/ng.361.

Kato N, Takeuchi F, Tabara Y, Kelly TN, Go MJ, Sim X, Tay WT: Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians. Nat Genet. 2011, 43: 531-538. 10.1038/ng.834.

Matsukawa N, Grzesik WJ, Takahashi N, Pandey KN, Pang S, Yamauchi M, Smithies O: The natriuretic peptide clearance receptor locally modulates the physiological effects of the natriuretic peptide system. Proc Natl Acad Sci USA. 1999, 96: 7403-7408. 10.1073/pnas.96.13.7403.

Lango Allen H, Estrada K, Lettre G, Berndt SI, Weedon MN, Rivadeneira F, Willer CJ: Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature. 2010, 467: 832-838. 10.1038/nature09410.

Jaubert J, Jaubert F, Martin N, Washburn LL, Lee BK, Eicher EM, Guénet JL: Three new allelic mouse mutations that cause skeletal overgrowth involve the natriuretic peptide receptor C gene (Npr3). Proc Natl Acad Sci USA. 1999, 96: 10278-10283. 10.1073/pnas.96.18.10278.