Human endothelial colony forming cells from adult peripheral blood have enhanced sprouting angiogenic potential through up-regulating VEGFR2 signaling

Leeper, 2010, Stem cell therapy for vascular regeneration: adult, embryonic, and induced pluripotent stem cells, Circulation, 122, 517, 10.1161/CIRCULATIONAHA.109.881441 Asahara, 2011, Concise review: circulating endothelial progenitor cells for vascular medicine, Stem Cells, 29, 1650, 10.1002/stem.745 Fadini, 2012, Critical reevaluation of endothelial progenitor cell phenotypes for therapeutic and diagnostic use, Circ. Res., 110, 624, 10.1161/CIRCRESAHA.111.243386 Ingram, 2004, Identification of a novel hierarchy of endothelial progenitor cells using human peripheral and umbilical cord blood, Blood, 104, 2752, 10.1182/blood-2004-04-1396 Critser, 2010, Endothelial colony-forming cell role in neoangiogenesis and tissue repair, Curr. Opin. Organ Transplant., 15, 68, 10.1097/MOT.0b013e32833454b5 Schwarz, 2012, Vascular incorporation of endothelial colony-forming cells is essential for functional recovery of murine ischemic tissue following cell therapy, Arterioscler. Thromb. Vasc. Biol., 32, e13, 10.1161/ATVBAHA.111.239822 Shepherd, 2006, Angiogenic cells can be rapidly mobilized and efficiently harvested from the blood following treatment with AMD3100, Blood, 108, 3662, 10.1182/blood-2006-06-030577 Reinisch, 2009, Humanized large-scale expanded endothelial colony-forming cells function in vitro and in vivo, Blood, 113, 6716, 10.1182/blood-2008-09-181362 Martin-Ramirez, 2012, Establishment of outgrowth endothelial cells from peripheral blood, Nat. Protoc., 7, 1709, 10.1038/nprot.2012.093 Joo, 2012, ROCK suppression promotes differentiation and expansion of endothelial cells from embryonic stem cell-derived Flk1(+) mesodermal precursor cells, Blood, 120, 2733, 10.1182/blood-2012-04-421610 Benedito, 2009, The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis, Cell, 137, 1124, 10.1016/j.cell.2009.03.025 Strasser, 2010, Microarray analysis of retinal endothelial tip cells identifies CXCR4 as a mediator of tip cell morphology and branching, Blood, 115, 5102, 10.1182/blood-2009-07-230284 Siemerink, 2012, CD34 marks angiogenic tip cells in human vascular endothelial cell cultures, Angiogenesis, 15, 151, 10.1007/s10456-011-9251-z Vanderslice, 1998, Angiogenesis induced by tumor necrosis factor-agr; is mediated by alpha4 integrins, Angiogenesis, 2, 265, 10.1023/A:1009296700991 Swift, 2009, Arterial–venous specification during development, Circ. Res., 104, 576, 10.1161/CIRCRESAHA.108.188805 Kim, 2010, LEC fate regulators: the 3 musketeers, Blood, 116, 4, 10.1182/blood-2010-04-278556 Alajati, 2008, Spheroid-based engineering of a human vasculature in mice, Nat. Methods, 5, 439, 10.1038/nmeth.1198 Melero-Martin, 2007, In vivo vasculogenic potential of human blood-derived endothelial progenitor cells, Blood, 109, 4761, 10.1182/blood-2006-12-062471 Mund, 2012, Flow cytometric identification and functional characterization of immature and mature circulating endothelial cells, Arterioscler. Thromb. Vasc. Biol., 32, 1045, 10.1161/ATVBAHA.111.244210 van Beem, 2009, Blood outgrowth endothelial cells from cord blood and peripheral blood: angiogenesis-related characteristics in vitro, J. Thromb. Haemost: JTH, 7, 217, 10.1111/j.1538-7836.2008.03192.x Tura, 2013, Late outgrowth endothelial cells resemble mature endothelial cells and are not derived from bone marrow, Stem Cells, 31, 338, 10.1002/stem.1280 Campioni, 2013, In vitro characterization of circulating endothelial progenitor cells isolated from patients with acute coronary syndrome, PLoS One, 8, 10.1371/journal.pone.0056377 Michowitz, 2007, Circulating endothelial progenitor cells and clinical outcome in patients with congestive heart failure, Heart, 93, 1046, 10.1136/hrt.2006.102657 Fadini, 2006, Number and function of endothelial progenitor cells as a marker of severity for diabetic vasculopathy, Arterioscler. Thromb. Vasc. Biol., 26, 2140, 10.1161/01.ATV.0000237750.44469.88 Bompais, 2004, Human endothelial cells derived from circulating progenitors display specific functional properties compared with mature vessel wall endothelial cells, Blood, 103, 2577, 10.1182/blood-2003-08-2770 Smadja, 2007, Increased VEGFR2 expression during human late endothelial progenitor cells expansion enhances in vitro angiogenesis with up-regulation of integrin alpha(6), J. Cell. Mol. Med., 11, 1149, 10.1111/j.1582-4934.2007.00090.x Yan, 2012, Chemokine receptor CXCR7 mediates human endothelial progenitor cells survival, angiogenesis, but not proliferation, J. Cell. Biochem., 113, 1437, 10.1002/jcb.24015 Boyer-Di Ponio, 2014, Instruction of circulating endothelial progenitors in vitro towards specialized blood–brain barrier and arterial phenotypes, PLoS One, 9, e84179, 10.1371/journal.pone.0084179 Finkenzeller, 2007, In vitro angiogenesis properties of endothelial progenitor cells: a promising tool for vascularization of ex vivo engineered tissues, Tissue Eng., 13, 1413, 10.1089/ten.2006.0369 Sieminski, 2005, Improved microvascular network in vitro by human blood outgrowth endothelial cells relative to vessel-derived endothelial cells, Tissue Eng., 11, 1332, 10.1089/ten.2005.11.1332 Jeong, 2011, Sprouting angiogenesis under a chemical gradient regulated by interactions with an endothelial monolayer in a microfluidic platform, Anal. Chem., 83, 8454, 10.1021/ac202170e Nguyen, 2013, Biomimetic model to reconstitute angiogenic sprouting morphogenesis in vitro, Proc. Natl. Acad. Sci. U. S. A., 110, 6712, 10.1073/pnas.1221526110 Beets, 2013, Robustness in angiogenesis: notch and BMP shaping waves, Trends Genet.: TIG, 29, 140, 10.1016/j.tig.2012.11.008 Smadja, 2008, Bone morphogenetic proteins 2 and 4 are selectively expressed by late outgrowth endothelial progenitor cells and promote neoangiogenesis, Arterioscler. Thromb. Vasc. Biol., 28, 2137, 10.1161/ATVBAHA.108.168815 Liu, 2012, Vasculogenic and osteogenesis-enhancing potential of human umbilical cord blood endothelial colony-forming cells, Stem Cells, 30, 1911, 10.1002/stem.1164 Margheri, 2011, Endothelial progenitor cell-dependent angiogenesis requires localization of the full-length form of uPAR in caveolae, Blood, 118, 3743, 10.1182/blood-2011-02-338681 Au, 2008, Differential in vivo potential of endothelial progenitor cells from human umbilical cord blood and adult peripheral blood to form functional long-lasting vessels, Blood, 111, 1302, 10.1182/blood-2007-06-094318 Finkenzeller, 2009, Impaired in vivo vasculogenic potential of endothelial progenitor cells in comparison to human umbilical vein endothelial cells in a spheroid-based implantation model, Cell Prolif., 42, 498, 10.1111/j.1365-2184.2009.00610.x