Human cytomegalovirus infection enhances cell proliferation, migration and upregulation of EMT markers in colorectal cancer-derived stem cell-like cells

International Journal of Oncology - Tập 51 Số 5 - Trang 1415-1426 - 2017
Wan‐Huai Teo1, Hsin‐Pai Chen2, Jason C. Huang1, Yu‐Jiun Chan2
1Department of Biotechnology and Laboratory Science in Medicine, School of Biomedical Science and Engineering, National Yang-Ming University, Taipei, Taiwan, R.O.C.
2Division of Infectious Diseases, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, R.O.C.

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World Health Organization fact sheet CancerFebruary2017http://www.who.int/mediacentre/factsheets/fs297/en/

Tanaka, 2009, Colorectal carcinogenesis: Review of human and experimental animal studies, J Carcinog, 8, 5, 10.4103/1477-3163.49014

Moore, 2011, Colorectal cancer: Epidemiology, etiology, and molecular basis, The ASCRS Textbook of Colon and Rectal Surgery, 2nd edition, 669, 10.1007/978-1-4419-1584-9_38

Colussi, 2013, Molecular pathways involved in colorectal cancer: Implications for disease behavior and prevention, Int J Mol Sci, 14, 16365, 10.3390/ijms140816365

Markowitz, 2009, Molecular origins of cancer: Molecular basis of colorectal cancer, N Engl J Med, 361, 2449, 10.1056/NEJMra0804588

Jemal, 2011, Global cancer statistics, CA Cancer J Clin, 61, 69, 10.3322/caac.20107

Harkins, 2002, Specific localisation of human cytomegalovirus nucleic acids and proteins in human colorectal cancer, Lancet, 360, 1557, 10.1016/S0140-6736(02)11524-8

Chen, 2012, Human cytomegalovirus preferentially infects the neoplastic epithelium of colorectal cancer: A quantitative and histological analysis, J Clin Virol, 54, 240, 10.1016/j.jcv.2012.04.007

Chen, 2014, Tumoral presence of human cytomegalovirus is associated with shorter disease-free survival in elderly patients with colorectal cancer and higher levels of intratumoral interleukin-17, Clin Microbiol Infect, 20, 664, 10.1111/1469-0691.12412

Dimberg, 2013, Detection of cytomegalovirus DNA in colorectal tissue from Swedish and Vietnamese patients with colorectal cancer, Anticancer Res, 33, 4947

Bai, 2016, Human cytomegalovirus infection and colorectal cancer risk: A meta-analysis, Oncotarget, 7, 76735, 10.18632/oncotarget.12523

Crough, 2009, Immunobiology of human cytomegalovirus: From bench to bedside, Clin Microbiol Rev, 22, 76, 10.1128/CMR.00034-08

Murphy, 2003, Coding potential of laboratory and clinical strains of human cytomegalovirus, Proc Natl Acad Sci USA, 100, 14976, 10.1073/pnas.2136652100

Harkins, 2010, Detection of human cytomegalovirus in normal and neoplastic breast epithelium, Herpesviridae, 1, 8, 10.1186/2042-4280-1-8

Samanta, 2003, High prevalence of human cytomegalovirus in prostatic intraepithelial neoplasia and prostatic carcinoma, J Urol, 170, 998, 10.1097/01.ju.0000080263.46164.97

Melnick, 2012, Human cytomegalovirus and mucoepidermoid carcinoma of salivary glands: Cell-specific localization of active viral and oncogenic signaling proteins is confirmatory of a causal relationship, Exp Mol Pathol, 92, 118, 10.1016/j.yexmp.2011.10.011

Cobbs, 2002, Human cytomegalovirus infection and expression in human malignant glioma, Cancer Res, 62, 3347

Rahbar, 2013, Human cytomegalovirus infection levels in glioblastoma multiforme are of prognostic value for survival, J Clin Virol, 57, 36, 10.1016/j.jcv.2012.12.018

Stragliotto, 2013, Effects of valganciclovir as an add-on therapy in patients with cytomegalovirus-positive glioblastoma: A randomized, double-blind, hypothesis-generating study, Int J Cancer, 133, 1204, 10.1002/ijc.28111

Wolmer-Solberg, 2013, Frequent detection of human cytomegalovirus in neuroblastoma: A novel therapeutic target?, Int J Cancer, 133, 2351, 10.1002/ijc.28265

Michaelis, 2009, The story of human cytomegalovirus and cancer: Increasing evidence and open questions, Neoplasia, 11, 1, 10.1593/neo.81178

Söderberg-Nauclér, 1999, Human cytomegalovirus latency and reactivation - a delicate balance between the virus and its host's immune system, Intervirology, 42, 314, 10.1159/000053966

Reeves, 2007, Complex I binding by a virally encoded RNA regulates mitochondria-induced cell death, Science, 316, 1345, 10.1126/science.1142984

Cobbs, 2007, Human cytomegalovirus induces cellular tyrosine kinase signaling and promotes glioma cell invasiveness, J Neurooncol, 85, 271, 10.1007/s11060-007-9423-2

Cobbs, 2008, Modulation of oncogenic phenotype in human glioma cells by cytomegalovirus IE1-mediated mitogenicity, Cancer Res, 68, 724, 10.1158/0008-5472.CAN-07-2291

Fiallos, 2014, Human cytomegalovirus gene expression in long-term infected glioma stem cells, PLoS One, 9, e116178, 10.1371/journal.pone.0116178

Soroceanu, 2015, Cytomegalovirus immediate-early proteins promote stemness properties in glioblastoma, Cancer Res, 75, 3065, 10.1158/0008-5472.CAN-14-3307

Fornara, 2016, Cytomegalovirus infection induces a stem cell phenotype in human primary glioblastoma cells: Prognostic significance and biological impact, Cell Death Differ, 23, 261, 10.1038/cdd.2015.91

Abdul Khalek, 2010, Colon cancer stem cells, Gastrointest Cancer Res, S16

Papailiou, 2011, Stem cells in colon cancer. A new era in cancer theory begins, Int J Colorectal Dis, 26, 1, 10.1007/s00384-010-1022-6

Du, 2008, CD44 is of functional importance for colorectal cancer stem cells, Clin Cancer Res, 14, 6751, 10.1158/1078-0432.CCR-08-1034

Gorham, 1996, Cellular distribution of CD44 gene transcripts in colorectal carcinomas and in normal colonic mucosa, J Clin Pathol, 49, 482, 10.1136/jcp.49.6.482

Wu, 1992, Localization of the human cytomegalovirus 2.7-kb major early beta-gene transcripts by RNA in situ hybridization in permissive and nonpermissive infections, Am J Pathol, 141, 1247

Cano, 2000, The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression, Nat Cell Biol, 2, 76, 10.1038/35000025

Yang, 2004, Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis, Cell, 117, 927, 10.1016/j.cell.2004.06.006

Mocarski, 2007, Cytomegaloviruses, Fields Virology, 5th edition, 2701

Fortunato, 1999, Regulation of human cytomegalovirus gene expression, Adv Virus Res, 54, 61, 10.1016/S0065-3527(08)60366-8

Landolfo, 2003, The human cytomegalovirus, Pharmacol Ther, 98, 269, 10.1016/S0163-7258(03)00034-2

Chen, 2015, Genetic polymorphisms of the human cytomegalovirus UL144 gene in colorectal cancer and its association with clinical outcome, J Gen Virol, 96, 3613, 10.1099/jgv.0.000308

Jiang, 2009, PI3K/PTEN signaling in angiogenesis and tumorigenesis, Adv Cancer Res, 102, 19, 10.1016/S0065-230X(09)02002-8

Suman, 2014, Activation of AKT signaling promotes epithelial-mesenchymal transition and tumor growth in colorectal cancer cells, Mol Carcinog, 53, E151, 10.1002/mc.22076

Porta, 2014, Targeting PI3K/Akt/mTOR signaling in cancer, Front Oncol, 4, 64, 10.3389/fonc.2014.00064

Mayer, 2016, The PI3K/AKT pathway as a target for cancer treatment, Annu Rev Med, 67, 11, 10.1146/annurev-med-062913-051343

Cobbs, 2014, HCMV glycoprotein B is expressed in primary glioblastomas and enhances growth and invasiveness via PDGFR-alpha activation, Oncotarget, 5, 1091, 10.18632/oncotarget.1787

Yurochko, 1995, Human cytomegalovirus upregulates NF-kappa B activity by transactivating the NF-kappa B p105/p50 and p65 promoters, J Virol, 69, 5391, 10.1128/JVI.69.9.5391-5400.1995

Castillo, 2000, Role of human cytomegalovirus immediate-early proteins in cell growth control, J Virol, 74, 8028, 10.1128/JVI.74.17.8028-8037.2000

Moorman, 2008, Human cytomegalovirus protein UL38 inhibits host cell stress responses by antagonizing the tuberous sclerosis protein complex, Cell Host Microbe, 3, 253, 10.1016/j.chom.2008.03.002

Streblow, 1999, The human cytomegalovirus chemokine receptor US28 mediates vascular smooth muscle cell migration, Cell, 99, 511, 10.1016/S0092-8674(00)81539-1

Maussang, 2006, Human cytomegalovirus-encoded chemokine receptor US28 promotes tumorigenesis, Proc Natl Acad Sci USA, 103, 13068, 10.1073/pnas.0604433103

Maussang, 2009, The human cytomegalovirus-encoded chemokine receptor US28 promotes angiogenesis and tumor formation via cyclooxygenase-2, Cancer Res, 69, 2861, 10.1158/0008-5472.CAN-08-2487

Slinger, 2010, HCMV-encoded chemokine receptor US28 mediates proliferative signaling through the IL-6-STAT3 axis, Sci Signal, 3, ra58, 10.1126/scisignal.2001180

Bongers, 2010, The cytomegalovirus-encoded chemokine receptor US28 promotes intestinal neoplasia in transgenic mice, J Clin Invest, 120, 3969, 10.1172/JCI42563

Cai, 2016, Human cytomegalovirus-encoded US28 may act as a tumor promoter in colorectal cancer, World J Gastroenterol, 22, 2789, 10.3748/wjg.v22.i9.2789

Ding, 2003, The pattern of enhancement of Src kinase activity on platelet-derived growth factor stimulation of glioblastoma cells is affected by the integrin engaged, J Biol Chem, 278, 39882, 10.1074/jbc.M304685200

Zhang, 2016, Signal transduction pathways of EMT induced by TGF-β, SHH, and WNT and their crosstalks, J Clin Med, 5, 41, 10.3390/jcm5040041

Derynck, 2014, Signaling pathway cooperation in TGF-β-induced epithelial-mesenchymal transition, Curr Opin Cell Biol, 31, 56, 10.1016/j.ceb.2014.09.001

Takebe, 2011, Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways, Nat Rev Clin Oncol, 8, 97, 10.1038/nrclinonc.2010.196

Takebe, 2015, Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: Clinical update, Nat Rev Clin Oncol, 12, 445, 10.1038/nrclinonc.2015.61

Gonzalez, 2014, Signaling mechanisms of the epithelial-mesenchymal transition, Sci Signal, 7, re8, 10.1126/scisignal.2005189

Jin, 2015, Epithelial-mesenchymal transition-associated microRNAs in colorectal cancer and drug-targeted therapies (Review), Oncol Rep, 33, 515, 10.3892/or.2014.3638

Bienz, 2000, Linking colorectal cancer to Wnt signaling, Cell, 103, 311, 10.1016/S0092-8674(00)00122-7

Polakis, 2000, Wnt signaling and cancer, Genes Dev, 14, 1837, 10.1101/gad.14.15.1837

Novellas de Munt, 2015, Targeting Wnt signaling in colorectal cancer. A review in the theme: Cell signaling: proteins, pathways and mechanisms, Am J Physiol Cell Physiol, 309, C511, 10.1152/ajpcell.00117.2015

Basu, 2016, Wnt signaling in cancer stem cells and colon cancer metastasis, F1000Res 5: F1000 Faculty Rev, 699

Brabletz, 2001, Variable beta-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment, Proc Natl Acad Sci USA, 98, 10356, 10.1073/pnas.171610498

Howard, 2011, A positive role of cadherin in Wnt/β-catenin signalling during epithelial-mesenchymal transition, PLoS One, 6, e23899, 10.1371/journal.pone.0023899

Ueno, 2009, Down-regulation of frizzled-7 expression decreases survival, invasion and metastatic capabilities of colon cancer cells, Br J Cancer, 101, 1374, 10.1038/sj.bjc.6605307

Nishioka, 2013, Possible involvement of Wnt11 in colorectal cancer progression, Mol Carcinog, 52, 207, 10.1002/mc.21845