Human Prion Protein Mutants with Deleted and Inserted Octarepeats Undergo Different Pathways to Trigger Cell Apoptosis
Tóm tắt
Từ khóa
Tài liệu tham khảo
Aguzzi A, Polymenidou M (2004) Mammalian prion biology: one century of evolving concepts. Cell 116:313–327
An R, Dong CF, Lei YJ et al (2008) PrP mutants with different numbers of octarepeat sequences are more susceptible to the oxidative stress. Sci China C Life Sci 51:630–639
Averous J, Bruhat A, Jousse C, Carraro V, Thiel G, Faournoux P (2004) Induction of CHOP expression by amino acid limitation requires both ATF4 expression and ATF2 phosphorylation. J Biol Chem 279:5288–5297
Brown DR, Besinger A (1998) Prion protein expression and superoxide dismutase activity. Biochem J 334:423–429
Brown DR, Qin K, Herms JW et al (1997) The cellular prion protein binds copper in vivo. Nature 390:684–687
Chen L, Yang Y, Han J et al (2007) Removal of the glycosylation of prion protein provokes apoptosis in SF126. J Biochem Mol Biol 41:662–669
Cherasse Y, Maurin AC, Chaveroux C et al (2007) The p300/CBP-associated factor (PCAF) is a cofactor of ATF4 for amino acid-regulated transcription of CHOP. Nucleic Acids Res 35:5954–5965
Collinge J, Palmer MS, Sidle KC et al (1995) Transmission of the familial insomnia to laboratory animals. Lancet 346:569–570
Dong CF, Shi S, Wang XF et al (2008) The N-terminus of PrP is responsible for interacting with tubulin and fCJD related PrP mutants possess stronger inhibitive effect on microtubule assembly in vitro. Arch Biochem Biophys 480:83–92
Flechsig E, Shmerling D, Hegyi L et al (2000) Prion protein devoid of the octapeptide repeat region restores susceptibility to scrapie in PrP knockout mice. Neuro 27:399–408
Goldfarb LG, Brown P, McCombie WR et al (1991) Transmissible familial Creutzfeldt-Jakob disease associated with five, seven, and eight extra octapeptide coding repeats in the PRNP gene. Proc Natl Acad Sci U S A 88:10926–10930
Harris DA (2003) Trafficking, turnover and membrane topology of PrP: protein function in prion disease. Br Med Bull 66:71–85
Hegde RS, Rane NS (2003) Prion protein trafficking and the development of neurodegeneration. Trends Neurosci 26:337–339
Hegde RS, Mastrianni JA, Scott MR et al (1998) A transmembrane form of the prion protein in neurodegenerative disease. Science 279:827–834
Hetz C, Russelakis-Carneiro M, Maundrell K, Castilla J, Soto C (2003) Caspase-12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein. EMBO J 22:5435–5445
Hornshaw MP, McDermott JR, Candy JM (1995) Copper binding to the N-terminal tandem repeat region of mammalian and avian prion protein: structural studies using synthetic peptides. Biochem Biophys Res Commun 207:621–629
Hosoi T, Hyoda K, Okuma Y, Nomura Y, Ozawa K (2007) Geldanamycin induces CHOP expression through a 4-(2-amimoethyl)-benzenesulfonyl fluoride-responsive serine protease. Cell Res 17:184–186
Hosoi T, Sasaki M, Baba S, Ozawa K (2009) Effect of pranoprofen on endoplasmic reticulum stress in the primary cultured glial cells. Neurochem Int 54:1–6
Lindholm D, Wootz H, Korhonen L (2006) ER stress and neurodegenerative disease. Cell Death Differ 13:385–392
Pauly PC, Harris DA (1998) Copper stimulates endocytosis of the prion protein. J Biol Chem 273:33107–33110
Prusiner SB, Groth D, Serban A et al (1993) Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti-PrP antibodies. Proc Natl Acad Sci U S A 90:10608–10612
Suzette A, Priola B, Chesebro B (1998) Abnormal properties of prion protein with insertional mutations in different cell types. J Biol Chem 273:11980–11985
Wang XZ, Harding HP, Zhang Y, Jolicoeur EM, Kuroda M, Ron D (1998) Cloning of mammalian Ire1 reveals diversity in the ER stress responses. EMBO J 17:5708–5717
Wang Q, He ZZ, Zhang JH et al (2005) Overexpression of endoplasmic reticulum molecular chaperone Grp94 and Grp78 in human lung cancer tissues and its significance. Cancer Detect Prev 29:544–551
Wang XF, Guo YJ, Zhang BY et al (2007) Creutzfeldt-Jakob disease in a Chinese patient with a novel seven extra-repeat insertion in PRNP. J Neurol Neurosurg Psychiatry 78:201–203
Winklhofer KF, Tatzelt J (2006) The role of chaperones in Parkinson’s disease and prion diseases. Molecular Chaperones in Health and Diseases 172:221–258
Xuan B, Qian Z, Toriqoi E, Yu D (2009) Human cytomegalovirus protein pUL38 induces ATF4 expression, inhibits persistent JNK phosphorylation, and suppresses endoplasmic reticulum stress-induced cell death. J Virol 83:3463–3476
Yin SM, Yu SL, Li CY et al (2006) Prion proteins with insertion mutations have altered N-terminal conformation and increased ligand binding activity and are more susceptible to oxidative attack. J Biol Chem 281:10698–10705
Yoshida H, Matsui T, Yamamoto A, Okada T, Mori K (2001) XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress produce a highly active transcription factor. Cell 107:881–891