Human MUC4 mucin induces ultra-structural changes and tumorigenicity in pancreatic cancer cells
Tóm tắt
Từ khóa
Tài liệu tham khảo
Alos L, Lujan B, Castillo M, Nadal A, Carreras M, Caballero M, de BC, Cardesa A (2005) Expression of membrane-bound mucins (MUC1 and MUC4) and secreted mucins (MUC2, MUC5AC, MUC5B, MUC6 and MUC7) in mucoepidermoid carcinomas of salivary glands. Am J Surg Pathol 29: 806–813
Andrianifahanana M, Agrawal A, Singh AP, Moniaux N, Van SI, Aubert JP, Meza J, Batra SK (2005) Synergistic induction of the MUC4 mucin gene by interferon-gamma and retinoic acid in human pancreatic tumour cells involves a reprogramming of signalling pathways. Oncogene 24: 6143–6154
Andrianifahanana M, Moniaux N, Schmied BM, Ringel J, Friess H, Hollingsworth MA, Buchler MW, Aubert JP, Batra SK (2001) Mucin (MUC) gene expression in human pancreatic adenocarcinoma and chronic pancreatitis: a potential role of MUC4 as a tumor marker of diagnostic significance. Clin Cancer Res 7: 4033–4040
Audie JP, Janin A, Porchet N, Copin MC, Gosselin B, Aubert JP (1993) Expression of human mucin genes in respiratory, digestive, and reproductive tracts ascertained by in situ hybridization. J Histochem Cytochem 41: 1479–1485
Audie JP, Tetaert D, Pigny P, Buisine MP, Janin A, Aubert JP, Porchet N, Boersma A (1995) Mucin gene expression in the human endocervix. Hum Reprod 10: 98–102
Balague C, Gambus G, Carrato C, Porchet N, Aubert JP, Kim YS, Real FX (1994) Altered expression of MUC2, MUC4, and MUC5 mucin genes in pancreas tissues and cancer cell lines. Gastroenterology 106: 1054–1061
Bax DA, Haringsma J, Einerhand AW, van DH, Blok P, Siersema PD, Kuipers EJ, Kusters JG (2004) MUC4 is increased in high grade intraepithelial neoplasia in Barrett's oesophagus and is associated with a proapoptotic Bax to Bcl-2 ratio. J Clin Pathol 57: 1267–1272
Bernardi P, Scorrano L, Colonna R, Petronilli V, Di Lisa F (1999) Mitochondria and cell death Eur. J Biochem 264: 687–701
Brand KA, Hermfisse U (1997) Aerobic glycolysis by proliferating cells: a protective strategy against reactive oxygen species. FASEB J 11: 388–395
Buisine MP, Devisme L, Copin MC, Durand-Reville M, Gosselin B, Aubert JP, Porchet N (1999) Developmental mucin gene expression in the human respiratory tract. Am J Respir Cell Mol Biol 20: 209–218
Buisine MP, Devisme L, Savidge TC, Gespach C, Gosselin B, Porchet N, Aubert JP (1998) Mucin gene expression in human embryonic and fetal intestine. Gut 43: 519–524
Carraway KL, Price-Schiavi SA, Komatsu M, Idris N, Perez A, Li P, Jepson S, Zhu X, Carvajal ME, Carraway CA (2000) Multiple facets of sialomucin complex/MUC4, a membrane mucin and erbb2 ligand, in tumors and tissues (Y2K update). Front Biosci 5: D95–D107
Chaturvedi P, Singh AP, Moniaux N, Senapati S, Chakraborty S, Meza JL, Batra SK (2007) MUC4 mucin potentiates pancreatic tumor cell proliferation, survival, and invasive properties and interferes with its interaction to extracellular matrix proteins. Mol Cancer Res 5: 309–320
Choudhury A, Moniaux N, Winpenny JP, Hollingsworth MA, Aubert JP, Batra SK (2000a) Human MUC4 mucin cDNA and its variants in pancreatic carcinoma. J Biochem (Tokyo) 128: 233–243
Choudhury A, Singh RK, Moniaux N, El-Metwally TH, Aubert JP, Batra SK (2000b) Retinoic acid dependent transforming growth factor-beta2-mediated induction of MUC4 mucin expression in human pancreatic tumor cells follows retinoic acid receptor-alpha signaling pathway. J Biol Chem 275: 33929–33936
Denecker G, Vercammen D, Steemans M, Berghe TV, Brouckaert G, Loo GV, Zhivotovsky B, Fiers W, Grooten J, Declercq W, Vandenabeele P (2001) Death receptor-induced apoptotic and necrotic cell death:differential role of caspases and mitochondria. Cell Death Differ 8: 829–840
Dietze EC, Caldwell LE, Grupin SL, Mancini M, Seewaldt VL (2001) Tamoxifen but not 4-hydroxytamoxifen initiates apoptosis in p53(-) normal human mammary epithelial cells by inducing mitochondrial depolarization. J Biol Chem 276: 5384–5394
Escande F, Lemaitre L, Moniaux N, Batra SK, Aubert JP, Buisine MP (2002) Genomic organization of MUC4 mucin gene. Towards the characterization of splice variants. Eur J Biochem 269: 3637–3644
Handra-Luca A, Lamas G, Bertrand JC, Fouret P (2005) MUC1, MUC2, MUC4, and MUC5AC expression in salivary gland mucoepidermoid carcinoma: diagnostic and prognostic implications. Am J Surg Pathol 29: 881–889
Hofer MD, Kuefer R, Varambally S, Li H, Ma J, Shapiro GI, Gschwend JF, Hautmann RE, Sanda MG, Klaudia Giehl MG, Menke A, Chinnaiyan AM, Rubin MA (2004) The role of metastasis associated protein 1 in prostate cancer progression. Cancer Res 64: 825–829
Hollingsworth MA, Strawhecker JM, Caffrey TC, Mack DR (1994) Expression of MUC1, MUC2, MUC3 and MUC4 mucin mRNAs in human pancreatic and intestinal tumor cell lines. Int J Cancer 57: 198–203
Jhala N, Jhala D, Vickers SM, Eltoum I, Batra SK, Manne U, Eloubeidi M, Jones JJ, Grizzle WE (2006) Biomarkers in diagnosis of pancreatic carcinoma in fine-needle aspirates. Am J Clin Pathol 126: 572–579
Khorrami AM, Choudhury A, Andrianifahanana M, Varshney GC, Bhattacharyya SN, Hollingsworth MA, Kaufman B, Batra SK (2002) Purification and characterization of a human pancreatic adenocarcinoma mucin. J Biochem (Tokyo) 131: 21–29
Kluck RM, Bossy-Wetzel E, Green DR, Newmeyer DD (1997) The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science 275: 1132–1136
Komatsu M, Jepson S, Arango ME, Carothers Carraway CA, Carraway KL (2001) Muc4/sialomucin complex, an intramembrane modulator of ErbB2/HER2/Neu, potentiates primary tumor growth and suppresses apoptosis in a xenotransplanted tumor. Oncogene 20: 461–470
Langley RR, Carlisle R, Ma L, Specian RD, Gerritsen ME, Granger DN (2001) Endothelial expression of vascular adhesion molecule-1 correlates with metastatic pattern in spontaneous melanoma. Microcirculation 5: 335–345
Liu X, Kim CN, Yang J, Jemmerson R, Wang X (1996) Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell 86: 147–157
Mancini M, Anderson BO, Caldwell E, Sedghinasab M, Paty PB, Hockenbery DM (1997) Mitochondrial proliferation and paradoxical membrane depolarization during terminal differentiation and apoptosis in a human colon carcinoma cell line. J Cell Biol 138: 449–469
Nollet S, Moniaux N, Maury J, Petitprez D, Degand P, Laine A, Porchet N, Aubert JP (1998) Human mucin gene MUC4: organization of its 5′-region and polymorphism of its central tandem repeat array. Biochem J 332: 739–748
Ogata S, Uehara H, Chen A, Itzkowitz SH (1992) Mucin gene expression in colonic tissues and cell lines. Cancer Res 52: 5971–5978
Pagliacci MC, Spinozzi F, Migliorati G, Fumi G, Smacchia M, Grignani F, Riccardi C, Nicoletti I (1993) Genistein inhibits tumour cell growth in vitro but enhances mitochondrial reduction of tetrazolium salts: a further pitfall in the use of the MTT assay for evaluating cell growth and survival. Eur J Cancer 29A: 1573–1577
Park HU, Kim JW, Kim GE, Bae HI, Crawley SC, Yang SC, Gum Jr J, Batra SK, Rousseau K, Swallow DM, Sleisenger MH, Kim YS (2003) Aberrant Expression of MUC3 and MUC4 membrane-associated mucins and sialyl lex antigen in pancreatic intraepithelial neoplasia. Pancreas 26: 48–54
Porchet N, Nguyen VC, Dufosse J, Audie JP, Guyonnet-Duperat V, Gross MS, Denis C, Degand P, Bernheim A, Aubert JP (1991) Molecular cloning and chromosomal localization of a novel human tracheo-bronchial mucin cDNA containing tandemly repeated sequences of 48 base pairs. Biochem Biophys Res Commun 175: 414–422
Renis M, Cantatore P, Loguercio PP, Fracasso F, Gadaleta MN (1989) Content of mitochondrial DNA and of three mitochondrial RNAs in developing and adult rat cerebellum. J Neurochem 52: 750–754
Robin ED, Wong R (1988) Mitochondrial DNA molecules and virtual number of mitochondria per cell in mammalian cells. J Cell Physiol 136: 507–513
Sazer S, Sherwood SW (1990) Mitochondrial growth and DNA synthesis occur in the absence of nuclear DNA replication in fission yeast. J Cell Sci 97: 509–516
Shay JW, Pierce DJ, Werbin H (1990) Mitochondrial DNA copy number is proportional to total cell DNA under a variety of growth conditions. J Biol Chem 265: 14802–14807
Singh AP, Moniaux N, chauhan SC, Meza JL, Batra SK (2004) Inhibition of MUC4 expression suppresses pancreatic tumor cell growth and metastasis. Cancer Res 64: 622–630
Swart MJ, Batra SK, Varshney GC, Hollingsworth MA, Yeo CJ, Cameron JL, Willentz RE, Hruban RH, Argani P (2002) MUC4 expression increases progressively in pancreatic intraepithelial neoplasia (PanIN). Am J Clin Pathol 117: 791–796
von Wangenheim KH, Peterson HP (1998) Control of cell proliferation by progress in differentiation: clues to mechanisms of aging, cancer causation and therapy. J Theor Biol 193: 663–678
Weed DT, Gomez-Fernandez C, Yasin M, Hamilton-Nelson K, Rodriguez M, Zhang J, Carraway KL (2004) MUC4 and ErbB2 expression in squamous cell carcinoma of the upper aerodigestive tract: correlation with clinical outcomes. Laryngoscope 114: 1–32