How well are we translating biofilm research from bench-side to bedside?

Mack, 1975, Microbial film development in a trickling filter, Microb Ecol, 2, 215, 10.1007/BF02010441 Nishimura, 1994, [Therapeutic study on biofilm of the urinary tract using a severely complicated bladder model (biofilm model of the urinary tract)--experimental study using an automatic simulator of urinary antimicrobial agent concentration, and clinical study], Kansenshogaku Zasshi, 68, 386, 10.11150/kansenshogakuzasshi1970.68.386 Domenico, P. Metal/thiol biocides. United States Patent 6,248,371 (2000). Philip, D. Metal/thiol biocides. United States Patent 6,248,371 (2001). Wolcott, 2010, Chronic wounds and the medical biofilm paradigm, J Wound Care, 19, 45, 10.12968/jowc.2010.19.2.46966 Wong, 2019, Estimation of clinical trial success rates and related parameters, Biostatistics, 20, 273, 10.1093/biostatistics/kxx069 Moore, 2018, Estimated costs of pivotal trials for novel therapeutic agents approved by the US food and drug administration, 2015-2016, JAMA Intern Med, 178, 1451, 10.1001/jamainternmed.2018.3931 Lu, 2019, Honey can inhibit and eliminate biofilms produced by Pseudomonas aeruginosa, Sci Rep, 9, 18160, 10.1038/s41598-019-54576-2 Reichling, 2020, Anti-biofilm and virulence factor-reducing activities of essential oils and oil components as a possible option for bacterial infection control, Planta Med