Hospital Epidemiology and Infection Control in Acute-Care Settings

Clinical Microbiology Reviews - Tập 24 Số 1 - Trang 141-173 - 2011
Emily Sydnor1, Trish M. Perl2,1
1Department of Medicine, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland
2Department of Hospital Epidemiology and Infection Control, Johns Hopkins University School of Medicine, Baltimore, Maryland

Tóm tắt

SUMMARY

Health care-associated infections (HAIs) have become more common as medical care has grown more complex and patients have become more complicated. HAIs are associated with significant morbidity, mortality, and cost. Growing rates of HAIs alongside evidence suggesting that active surveillance and infection control practices can prevent HAIs led to the development of hospital epidemiology and infection control programs. The role for infection control programs has grown and continues to grow as rates of antimicrobial resistance rise and HAIs lead to increasing risks to patients and expanding health care costs. In this review, we summarize the history of the development of hospital epidemiology and infection control, common HAIs and the pathogens causing them, and the structure and role of a hospital epidemiology and infection control program.

Từ khóa


Tài liệu tham khảo

Ahmad, K. 2007. Kazakhstan health workers stand trial for HIV outbreak. Lancet Infect. Dis. 7 : 311.

10.2307/30141232

10.1001/archinte.166.12.1289

10.7326/0003-4819-77-5-691

10.2307/30148417

American Institute of Architects. 2010. Guidelines for design and construction of hospital and health care facilities. Facility Guidelines Institute Dallas TX. http://www.fgiguidelines.org/2010guidelines.html.

10.1164/rccm.200405-644ST

10.1086/599814

10.1086/338958

10.1086/524334

10.1016/j.ajic.2006.11.007

Arnow, P. M., R. L. Andersen, P. D. Mainous, and E. J. Smith. 1978. Pumonary aspergillosis during hospital renovation. Am. Rev. Respir. Dis. 118 : 49-53.

10.1086/650752

10.1016/0195-6701(89)90110-2

10.7326/0003-4819-145-10-200611210-00008

10.1186/1471-2334-6-21

10.1016/j.jhin.2005.05.003

10.1016/j.arcmed.2005.02.005

10.1128/CMR.13.3.385

10.1353/pbm.2005.0068

10.1097/01.CCM.0000142399.70913.2F

10.1007/s001340100979

10.1086/652648

10.2307/30142404

10.7326/0003-4819-122-9-199505010-00003

10.1056/NEJMoa0808939

10.1093/oxfordjournals.ndt.a091872

Boelaert, J. R., et al. 1993. Nasal mupirocin ointment decreases the incidence of Staphylococcus aureus bacteraemias in haemodialysis patients. Nephrol. Dial. Transplant. 8 : 235-239.

10.1164/ajrccm.154.5.8912745

10.1086/533590

10.1086/589906

10.2307/30141115

10.1128/jcm.32.5.1148-1153.1994

10.1086/421495

10.2174/138945005774912717

10.1001/archinte.165.12.1430

10.1177/000313480607201106

10.1001/archinte.165.10.1179

10.1056/NEJM198905043201806

10.1056/NEJMhpr020557

10.1097/01.CCM.0000094217.07170.75

Byers, K. E., et al. 1998. Disinfection of hospital rooms contaminated with vancomycin-resistant Enterococcus faecium. Infect. Control Hosp. Epidemiol. 19 : 261-264.

10.1086/591061

10.1056/NEJM199711203372101

10.1086/591940

10.1016/j.cld.2009.11.003

10.1111/j.1469-0691.2009.03115.x

10.1001/archinte.162.19.2223

10.1001/archinte.159.10.1127

10.1097/01.SMJ.0000050683.36014.2E

10.1001/jama.1991.03470060033005

Centers for Disease Control and Prevention. 2008. Acute hepatitis C virus infections attributed to unsafe injection practices at an endoscopy clinic—Nevada, 2007. MMWR Morb. Mortal. Wkly. Rep. 57 : 513-517.

Centers for Disease Control and Prevention. 2010. Detection of Enterobacteriaceae isolates carrying metallo-beta-lactamase—United States, 2010. MMWR Morb. Mortal. Wkly. Rep. 59 : 750.

Centers for Disease Control and Prevention. 2002. Exophiala infection from contaminated injectable steroids prepared by a compounding pharmacy—United States July-November 2002. MMWR Morb. Mortal. Wkly. Rep. 51 : 1109-1112.

Centers for Disease Control and Prevention. 1999. Four pediatric deaths from community-acquired methicillin-resistant Staphylococcus aureus—Minnesota and North Dakota, 1997-1999. JAMA 282 : 1123-1125.

Centers for Disease Control and Prevention. 2009. Guidance for control of infections with carbapenem-resistant or carbapenemase-producing Enterobacteriaceae in acute care facilities. MMWR Morb. Mortal. Wkly. Rep. 58 : 256-260.

Centers for Disease Control and Prevention. 2000. Guidelines for preventing opportunistic infections among hematopoietic stem cell transplant recipients. MMWR Recommend. Rep. 49 : 1-125.

Centers for Disease Control and Prevention. 2009. Interim guidance on infection control measures for 2009 H1N1 influenza in healthcare settings including protection of healthcare personnel. Centers for Disease Control and Prevention Atlanta GA. http://www.cdc.gov/h1n1flu/guidelines_infection_control.htm.

Centers for Disease Control and Prevention. 2010. Prevention strategies for seasonal influenza in healthcare settings. Centers for Disease Control and Prevention Atlanta GA. http://www.cdc.gov/flu/pdf/infectioncontrol_seasonalflu_ICU2010.pdf.

Centers for Disease Control and Prevention. 2005. Severe Clostridium difficile-associated disease in populations previously at low risk—four states, 2005. MMWR Morb. Mortal. Wkly. Rep. 54 : 1201-1205.

Centers for Disease Control and Prevention. 1995. Vaccination coverage of 2-year-old children—United States, January-March, 1994. MMWR Morb. Mortal. Wkly. Rep. 44 : 142-143, 149-150.

10.1016/S0924-8579(09)70562-X

10.1086/502540

10.1086/592984

10.1056/NEJM199407073310104

10.7326/0003-4819-116-10-798

10.1128/jcm.27.10.2386-2387.1989

10.2307/30141515

Performance standards for antimicrobial susceptibility testing. 2009

10.1080/00028899908984481

10.1086/524332

10.1086/651706

10.1053/jhin.2002.1258

Cortese, M. M., and U. D. Parashar. 2009. Prevention of rotavirus gastroenteritis among infants and children: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recommend. Rep. 58 : 1-25.

10.1086/499406

10.1086/502522

10.1086/345476

10.1016/S0002-9343(97)00003-X

10.1016/j.jcv.2007.11.006

10.1056/NEJMoa0810988

10.1023/A:1001738823146

10.1016/S0163-4453(98)80173-4

10.1086/430909

10.1164/ajrccm.160.3.9808145

10.1086/502178

10.1086/591065

10.1086/592981

10.1086/514761

10.1086/587987

10.1016/j.ajic.2009.10.001

10.1086/502043

10.1086/367653

10.1056/NEJM199602293340902

10.1097/01.CCM.0000251496.61520.75

10.1016/0002-9343(91)90535-6

10.1111/j.1445-5994.2009.02004.x

Tuberculosis in the workplace. 2001

10.1016/j.vaccine.2004.08.017

10.1056/NEJMra064928

10.1128/AAC.48.7.2431-2436.2004

10.1086/500202

10.1086/514553

10.1016/j.jhin.2004.03.006

10.1097/00002030-200305230-00010

Ganczak, M., and P. Barss. 2008. Nosocomial HIV infection: epidemiology and prevention—a global perspective. AIDS Rev. 10 : 47-61.

10.1086/313694

10.1086/345921

10.1016/j.ajog.2008.05.001

10.1016/0196-6553(88)90053-3

10.1086/432803

10.1086/341304

10.1128/AAC.01169-07

10.1067/mai.2002.125337

10.1086/502596

10.1086/533494

10.1093/infdis/138.5.625

10.1128/AAC.35.11.2180

10.1128/JCM.42.4.1519-1527.2004

10.1086/322970

10.1093/oxfordjournals.aje.a113990

10.1016/S0196-6553(85)80010-9

10.1093/oxfordjournals.aje.a112928

10.1086/313960

10.1056/NEJM197902223000803

10.1056/NEJM198607103150201

10.1128/AAC.43.6.1412

10.1001/jama.299.10.1149

10.1086/598513

10.1016/j.ajic.2006.09.011

Harris, A. D., J. C. McGregor, and J. P. Furuno. 2006. What infection control interventions should be undertaken to control multidrug-resistant Gram-negative bacteria? Clin. Infect. Dis. 43(Suppl. 2): S57-S61.

10.1086/522657

10.1093/jac/dkp256

10.1128/CMR.16.3.546-568.2003

10.1086/650298

10.1164/ajrccm.159.4.9807050

10.1086/591861

10.1093/clinids/9.6.1065

10.1016/0195-6701(89)90091-1

10.1016/j.ajic.2008.03.002

10.1111/j.1348-0421.1995.tb02207.x

10.1001/archinte.166.18.1945

10.1086/345955

10.1086/510622

10.1086/507636

10.1146/annurev.med.50.1.223

10.1159/000238624

10.1086/513764

10.1016/S1079-2104(98)90291-8

10.1016/j.jcv.2007.03.002

10.1056/NEJMoa022987

10.2307/30148476

10.1093/clinids/20.6.1526

10.1016/0196-6553(95)90259-7

10.1016/S0195-6701(07)60005-X

Jensen, P. A., L. A. Lambert, M. F. Iademarco, and R. Ridzon. 2005. Guidelines for preventing the transmission of Mycobacterium tuberculosis in health-care settings, 2005. MMWR Recommend. Rep. 54 : 1-141.

10.1086/605408

10.1086/520666

Comprehensive accreditation manual for hospitals: the official handbook. 2003

National patient safety goals. 2010

Accreditation manual for hospitals. 1976

10.1086/652152

10.1001/jama.2010.1115

10.1016/j.jhin.2004.12.005

10.1016/S0196-6553(99)70087-8

10.1016/S0732-8893(97)00068-0

10.1093/jac/dkq273

10.1097/00002030-199909100-00018

10.1016/S0140-6736(99)04196-3

10.2307/30146471

10.1128/CMR.7.1.117

10.1128/CMR.10.3.505

10.1086/596734

To err is human: building a safer health system. 2000

10.1093/infdis/173.4.822

Kretsinger, K., et al. 2006. Preventing tetanus, diphtheria, and pertussis among adults: use of tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine recommendations of the Advisory Committee on Immunization Practices (ACIP) and recommendation of ACIP, supported by the Healthcare Infection Control Practices Advisory Committee (HICPAC), for use of Tdap among health-care personnel. MMWR Recommend. Rep. 55 : 1-37.

10.1016/S1473-3099(10)70143-2

10.1128/JCM.01557-08

10.1086/501624

10.1086/319757

10.2146/ajhp070477

10.1128/AAC.00299-07

10.1056/NEJM198708063170601

10.1128/AAC.49.11.4555-4560.2005

Linnemann, C. C., Jr., N. Ramundo, P. H. Perlstein, S. D. Minton, and G. S. Englender. 1975. Use of pertussis vaccine in an epidemic involving hospital staff. Lancet ii : 540-543.

Respiratory protection for healthcare workers in the workplace against novel H1N1: a letter report. 2009

10.1086/591066

10.1001/jama.2009.1466

10.1128/AAC.00116-06

10.2307/30141134

10.1056/NEJM199808203390806

10.1086/520311

10.1007/s00134-005-2679-0

10.1056/NEJM199002223220804

10.1038/nature07822

10.1016/0140-6736(92)93088-5

10.1016/S0140-6736(08)61116-2

10.1001/archsurg.1997.01430250078017

10.1097/QCO.0b013e3283013945

10.1016/S0195-6701(03)00262-7

10.1086/529198

10.1159/000063224

10.1182/blood-2002-05-1496

10.1086/339202

10.1086/315193

10.1086/591059

Martin, M. A., M. A. Pfaller, and R. P. Wenzel. 1989. Coagulase-negative staphylococcal bacteremia. Mortality and hospital stay. Ann. Intern. Med. 110 : 9-16.

10.1002/1097-0142(19891115)64:10<2030::AID-CNCR2820641011>3.0.CO;2-2

10.1056/NEJMoa051590

10.3201/eid1205.051064

10.1056/NEJM198901263200402

10.1016/j.ajic.2005.09.006

10.1016/j.ajic.2005.04.001

10.1056/NEJM199501123320206

10.2307/30140946

10.1213/00000539-199404000-00005

10.1086/340399

10.1016/j.cld.2009.11.005

10.1086/529212

10.1016/j.vaccine.2007.03.046

Muder, R. R., C. Brennen, S. D. Drenning, J. E. Stout, and M. M. Wagener. 1997. Multiply antibiotic-resistant Gram-negative bacilli in a long-term-care facility: a case-control study of patient risk factors and prior antibiotic use. Infect. Control Hosp. Epidemiol. 18 : 809-813.

10.1016/j.jhin.2010.02.005

10.1111/j.1365-2222.1976.tb01899.x

10.1086/600391

10.1086/651097

10.1086/502213

10.1378/chest.114.1.251

10.1097/00126334-200302011-00011

10.1016/j.ajic.2004.10.001

10.1067/mic.2001.119952

10.1001/jama.1996.03530450062034

10.1001/jama.289.7.885

10.1592/phco.28.2.235

10.1017/S0950268807008746

10.1111/j.1469-0691.2009.03027.x

10.1590/S0036-46651995000500004

10.1017/S0195941700026072

Occupational Safety and Health Administration. 1991. Occupational exposure to bloodborne pathogens—OSHA. Final rule. Fed. Regist. 56 : 64004-64182.

Occupational Safety and Health Administration. 2010. Occupational safety and health standards. Occupational Safety and Health Administration Washington DC. http://www.osha.gov/pls/oshaweb/owadisp.show_document?p_table=STANDARDS&p_id=10051.

10.1093/infdis/150.6.808

10.4187/aarc0446

10.1002/ajh.1054

10.1086/502303

10.1097/MCP.0b013e3283292650

Panlilio, A. L., D. M. Cardo, L. A. Grohskopf, W. Heneine, and C. S. Ross. 2005. Updated U.S. Public Health Service guidelines for the management of occupational exposures to HIV and recommendations for postexposure prophylaxis. MMWR Recommend. Rep. 54 : 1-17.

Panlilio, A. L., et al. 1995. Serosurvey of human immunodeficiency virus, hepatitis B virus, and hepatitis C virus infection among hospital-based surgeons. Serosurvey Study Group. J. Am. Coll. Surg. 180 : 16-24.

10.1086/590062

10.1007/s00134-002-1276-8

10.1086/521852

Perl, T. M., and R. Chaiwarith. 2010. Surveillance: an overview, p. 111-142. In E. Lautenbach, K. F. Woeltje, and P. N. Malani (ed.), Practical healthcare epidemiology, 3rd ed. University of Chicago Press, Chicago, IL.

10.1056/NEJMoa003069

10.1177/106002809803200104

Perl, T. M., and M. C. Roy. 1995. Postoperative wound infections: risk factors and role of Staphylococcus aureus nasal carriage. J. Chemother. 7(Suppl. 3): 29-35.

10.1080/13693780701218689

10.1017/S0950268800067893

Petrosillo, N., L. Pagani, and G. Ippolito. 2003. Nosocomial infections in HIV-positive patients: an overview. Infection 31(Suppl. 2): 28-34.

10.1097/00002030-199904010-00009

10.1086/338813

10.1016/0195-6701(95)90036-5

10.1086/323126

10.1086/501554

Pittet, D., et al. 2000. Effectiveness of a hospital-wide programme to improve compliance with hand hygiene. Infection Control Programme. Lancet 356 : 1307-1312.

10.1001/jama.1994.03510440058033

10.1055/s-0028-1119806

10.1086/528716

10.1056/NEJMoa061115

10.1016/S0002-9343(96)00014-9

10.1093/clinids/23.5.1020

10.1086/501967

10.1016/j.diagmicrobio.2007.03.011

10.1086/656210

10.1016/S1079-2104(97)90061-5

10.1086/593956

Resar, R., et al. 2005. Using a bundle approach to improve ventilator care processes and reduce ventilator-associated pneumonia. Jt. Comm. J. Qual. Patient Saf. 31 : 243-248.

10.1097/00003246-200210000-00008

10.1016/j.amjmed.2006.03.012

Rice, L. B. 2006. Antimicrobial resistance in Gram-positive bacteria. Am. J. Infect. Control 34 : S11-S19, S64-S73.

10.1086/605630

10.7326/0003-4819-148-6-200803180-00003

10.1086/597550

Rolain, J. M., P. Parola, and G. Cornaglia. 2010. New Delhi metallo-beta-lactamase (NDM-1): towards a new pandemia? Clin. Microbiol. Infect. 15(Suppl. 2): 98-99.

Roth, V. R., and M. Loeb. 2010. Administering an infection prevention program, p. 403-406. In E. Lautenbach, K. F. Woeltje, and P. N. Malani (ed.), Practical healthcare epidemiology, 3rd ed. University of Chicago Press, Chicago, IL.

Ruhl, L., and L. A. Herwaldt. 2010. Infection prevention in construction and renovation, p. 439-462. In E. Lautenbach, K. F. Woeltje, and P. N. Malani (ed.), Practical healthcare epidemiology, 3rd ed. University of Chicago Press, Chicago, IL.

Rutala, W. A. 1996. APIC guideline for selection and use of disinfectants. 1994, 1995, and 1996 APIC Guidelines Committee. Association for Professionals in Infection Control and Epidemiology, Inc. Am. J. Infect. Control 24 : 313-342.

Rutala W. A and D. Weber. 2008. Healthcare Infection Control Practices Advisory Committee. Guideline for disinfection and sterilization in healthcare facilities. Centers for Disease Control and Prevention Atlanta GA. http://www.cdc.gov/hicpac/Disinfection_Sterilization/table_10.html.

10.1086/423182

10.1097/01.CCM.0000181731.53912.D9

10.1016/j.ajic.2006.01.011

10.1086/592299

10.1086/503485

10.1016/S0196-6553(02)48250-8

10.1086/500624

10.1002/1097-0142(20010915)92:6<1349::AID-CNCR1457>3.0.CO;2-E

10.1093/clinids/19.6.1123

10.1016/S0196-6553(98)70061-6

10.2307/30142002

10.1186/1471-2334-6-80

Reference deleted.

10.1016/0002-9343(87)90902-8

Shojania, K. G., B. W. Duncan, K. M. McDonald, R. M. Wachter, and A. J. Markowitz. 2001. Making health care safer: a critical analysis of patient safety practices. Evid. Rep. Technol. Assess. (Summ.) 2001 : 1-668.

10.1086/512627

Siegel, J. D., et al. 2007. 2007 guideline for isolation precautions: preventing transmission of infectious agents in healthcare settings. Am. J. Infect. Control 35(Suppl. 2): S65-S164.

10.1016/j.ajic.2007.10.006

10.1086/510392

10.1016/j.jhin.2009.07.004

10.1592/phco.19.12.129S.31702

10.2307/30141404

10.1093/jac/dkg124

10.1056/NEJM199203053261011

Society for Healthcare Epidemiology of America. 2009. Interim guidance on infection control precautions for novel swine-origin influenza A H1N1 in healthcare facilities. Society for Healthcare Epidemiology of America Arlington VA. www.shea-online.org/Assets/files/policy/061209_H1N1_Statement.pdf.

10.1086/502196

10.7326/0003-4819-118-2-199301150-00008

Srinivasan, A., and W. R. Jarvis. 2010. Outbreak investigations, p. 143-155. In E. Lautenbach, K. F. Woeltje, and P. N. Malani (ed.), Practical healthcare epidemiology, 3rd ed. University of Chicago Press, Chicago, IL.

10.1001/jama.290.14.1899

10.1128/JCM.39.3.949-953.2001

10.1016/j.ajic.2005.04.246

10.1016/j.ajic.2008.11.001

Reference deleted.

10.1086/500408

10.2307/30141187

10.1086/320893

10.1016/j.ijantimicag.2007.08.026

10.1086/501964

10.1016/S0195-6701(98)90074-3

10.1098/rsif.2009.0302.focus

10.1016/j.ijantimicag.2007.07.033

10.1128/JCM.00427-10

10.1086/501691

10.1001/jama.1992.03480210061033

10.1086/425000

U.S. Congress. 2007. Community and healthcare-associated infections reduction act of 2007. S.2278. 110th U.S. Congress Washington DC. http://www.govtrack.us/congress/bill.xpd?bill=s110-2278.

10.7326/0003-4819-135-7-200110020-00007

10.1086/502205

10.1128/AAC.00186-06

10.1016/0016-5085(81)90644-2

10.1056/NEJM200101043440102

10.1086/516480

10.1001/jama.298.23.2782

10.1378/chest.114.1.131

10.1016/S0140-6736(05)67420-X

Wasley, A., S. Grytdal, and K. Gallagher. 2008. Surveillance for acute viral hepatitis—United States, 2006. MMWR Surveill. Summ. 57 : 1-24.

10.1086/501924

10.2307/30141559

Weber, D. J., and R. P. Wenzel. 1997. Environmental issues and nosocomial infections, p. 491-514. In R. P. Wenzel (ed.), Prevention and control of nosocomial infections. Williams & Wilkins, Baltimore, MD.

10.1086/512261

10.1007/BF01967787

Wenzel, R. P. 1995. The Lowbury Lecture. The economics of nosocomial infections. J. Hosp. Infect. 31 : 79-87.

10.1093/oxfordjournals.aje.a112223

10.1016/0195-6701(95)90079-9

10.1017/S0195941700059774

10.7326/0003-4819-97-3-367

10.1086/500372

10.1001/archinte.1989.00390100145030

10.1046/j.1524-4733.2002.51108.x

10.1086/421946

10.1086/374339

10.1086/502528

World Health Organization. 2009. Infection prevention and control in health care for confirmed or suspected cases of pandemic (H1N1) 2009 and influenza-like illnesses. World Health Organization Geneva Switzerland. http://www.who.int/csr/resources/publications/SwineInfluenza_infectioncontrol.pdf.

10.1086/502400

10.1086/502129

10.1111/j.1469-0691.2009.02836.x

10.1128/AAC.45.4.1151-1161.2001

10.1038/bmt.2009.261

10.1086/591063

10.1086/591060

10.1128/AAC.00774-09

10.1056/NEJM198607103150204

10.1086/496922

10.3109/1040841X.2010.481763

10.1086/587187

10.1016/S0272-6386(12)80883-3