Histologic study of bone-forming capacity on polydeoxyribonucleotide combined with demineralized dentin matrix

Rubegni P, De Aloe G, Mazzatenta C, Cattarini L, Fimiani M (2001) Clinical evaluation of the trophic effect of polydeoxyribonucleotide (PDRN) in patients undergoing skin explants. A pilot study. Curr Med Res Opin 17:128–31

Kim KY, Yeo IS, Kim SG, Um IW, Kim YK (2011) Analysis of crystalline structure of autogenous tooth bone graft material: X-Ray diffraction analysis. J Korean Assoc Oral Maxillofac Surg 37:142–7

Kim YK et al. (2010) Development of a novel bone grafting material using autogenous teeth. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 109:496–503

Galeano M et al. (2008) Polydeoxyribonucleotide stimulates angiogenesis and wound healing in the genetically diabetic mouse. Wound Repair Regen 16:208–17

Bitto A et al. (2008) Polydeoxyribonucleotide improves angiogenesis and wound healing in experimental thermal injury. Crit Care Med 36:1594–602

Sini P, Denti A, Cattarini G, Daglio M, Tira ME, Balduini C (1999) Effect of polydeoxyribonucleotides on human fibroblasts in primary culture. Cell Biochem Funct 17:107–14

Thellung S, Florio T, Maragliano A, Cattarini G, Schettini G (1999) Polydeoxyribonucleotides enhance the proliferation of human skin fibroblasts: involvement of A2 purinergic receptor subtypes. Life Sci 64(18):1661–74

Guizzardi S, Galli C, Govoni P, Boratto R, Cattarini G, Martini D, Belletti S, Scandroglio R (2003) Polydeoxyribonucleotide (PDRN) promotes human osteoblast proliferation: a new proposal for bone tissue repair. Life Sci 73(15):1973–83

Misch CE, Dietsh F (1993) Bone grafting materials in implant dentistry. Implant Dent 2:158–167

Urist MR, Strates BS (1971) Bone morphogenetic protein. J Dent Res 50:1392–1406

Cavallini M (2004) Biorevitalization and cosmetic surgery of the face: synergies of action. J Appl Cosmetol 22:125–132

Victor-Vega C, Desai A, Monesinos MC, Cronstein BN (2002) Adenosine A2A receptor agonists promote more rapid wound healing than recombinant human platelet-derived growth factor (Becaplermin gel). Inflammation 26:19–24

Montesinos MC, Desai A, Chen JF, Yee H, Schwarzschild MA, Fink JS, Cronstein BN (2002) Adenosine promotes wound healing and mediates angiogenesis in response to tissue injury via occupancy of A(2A) receptors. Am J Pathol 160:2009–18

Yamaoka T, Kondo M, Honda S, Iwahana H, Moritani M, Ii S, Yoshimoto K, Itakura M (1997) Amidophosphoribosyltransferase limits the rate of cell growth-linked de novo purine biosynthesis in the presence of constant capacity of salvage purine biosynthesis. J Biol Chem 272:1719

Carver JD (1994) Dietary nucleotides: cellular immune, intestinal and hepatic system effects. J Nutr 124:144–148

Abbracchio MP, Burnstock G (1998) Purinergic signalling: pathophysiological roles. Jpn J Pharmacol 78:113–45

Valdatta L, Thione A, Mortarino C, Buoro M, Tuinder S (2004) Evaluation of the efficacy of polydeoxyribonucleotides in the healing process of autologous skin graft donor sites: a pilot study. Curr Med Res Op 20:403–8

De Aloe G, Rubegni P, Biagioli M, Taddeucci P, Fimiani M (2004) Skin graft donor site and use of polydeoxyribonucleotide as a treatment for skin regeneration: a randomized, controlled, double-blind, clinical trial. Wounds 16:258–63