High-throughput screening approaches for investigating drug metabolism and pharmacokinetics

ABRAHAM M. H., 1995, Drug Design and Discovery, 13, 123

10.1021/js9901007

ANNAERT P. P., 2000, Drug Metabolism Reviews, 32, 198

10.1016/0006-291X(91)91647-U

AYRTON A., 2001, Xenobiotica, 31, 399, 10.1080/00498250110060969

AYRTON J., 1998, Rapid Communications in Mass Spectrometry, 12, 217, 10.1002/(SICI)1097-0231(19980314)12:5<217::AID-RCM146>3.0.CO;2-I

BAJPAI M., 2000, Current Opinions in Drug Discovery and Development, 3, 63

BAYLISS M. K., 1999, Current Opinions in Drug Discovery and Development, 2, 20

BERMAN J., 1997, Journal of Medicinal Chemistry, 40, 827, 10.1021/jm960702s

BERTRAND M., 2000, European Journal of Pharmaceutical Sciences, 11, 61, 10.1016/S0928-0987(00)00165-2

BEVAN C. D., 2000, Analytical Chemistry, 72, 787

BOWEN W. P., 2000, Drug Metabolism and Disposition, 28, 781

BOWERS W. F., 1984, Clinical Pharmaco kinetics, 9, 49, 10.2165/00003088-198400091-00007

CALDWELL G. W, 2000, Current Opinions in Drug Discovely and Development, 3, 30

CAMENISCH G., 1998, European Journal of Pharmaceutical Sciences, 6, 313, 10.1016/S0928-0987(97)10019-7

CARLILE D. J., 1997, Drug Metabolism and Disposition, 25, 903

10.1126/science.274.5287.610

10.1023/A:1018969222130

CHONG S., 1997, Pharmaceutical Research, 14, 1835, 10.1023/A:1012112820371

CLARK D. E, 1999, Journal of Pharmaceutical Sciences, 88, 4

10.1021/js980402t

COMMANDEUR J. N. M, 1999, Chimie Nouvelle, 17, 1994

Coous R. G., 1997, NATO ASI Series, 504, 213

CORCORAN O., 1999, Analytical Communications, 36, 259, 10.1039/a902513h

CRESPI C. L, 1999, Current Opinions in Drug Discovery and Development, 2, 15

CRESPI C. L, 1999, Pharmaceutical Science Technology Today, 2, 119, 10.1016/S1461-5347(99)00127-3

CRESPI C. L., 1997, Analytical Biochemistry, 248, 88, 10.1006/abio.1997.2145

CRESPI C. L., 1998, Medicinal Chemistry Research, 8, 457

CRESPI C. L., 1641, Pharmaceutical Research, 13, 1635–, 10.1023/A:1016428304366

CRONIN M, 1998, Pharmacy and Pharmacology Communications, 4, 157

10.1016/S0928-0987(00)00162-7

DARVAS F., 2000, Journal of Chemical Information and Computer Sciences, 40, 314, 10.1021/ci990268d

DE GROOT, M. J., ACKLAND, M. J., HORNE, V. A., ALEX, A. A. and JONES, B. C.,, 1999, Journal of Medicinal Chemistry, 42, 1515, 10.1021/jm981118h

DELIE F., 1997, Critical Review of Therapeutk Drug Carrier Systems, 14, 221

DIKE L. E., 2000, Drug Metabolism Reviews, 32, 183

EASTERLING M. L., 1997, NATO ASI Series, 504, 287

EDDERSHAW P. J., 2000, Drug Discoveiy Today, 5, 409, 10.1016/S1359-6446(00)01540-3

10.1021/jm000292e

EKINS S., 1995, Drug Metabolism and Disposition, 23, 279

10.1006/abio.1995.1290

ERHARDT P. W, 1998, Medicinal Chemistry Research, 8, 400

GEORGE A, 1999, Current Opinions in Drug Discovery and Development, 2, 286

GHOSAL A., 2000, Drug Metabolism Reviews, 32, 188

GIDDINGS S. J., 1997, European Journal of Drug Metabolism and Pharmacokinetics, 22, 315, 10.1007/BF03190963

GILBERT J. D., 1996, American Chemical Society Symposium Series, 619, 330, 10.1021/bk-1995-0619.ch017

GONZALEZ F. J., 1992, Tohoku Journal of Experimental Medicine, 168, 67, 10.1620/tjem.168.67

GRASS G. M, 1997, Advanced Drug Delivery Reviews, 23, 199, 10.1016/S0169-409X(96)00436-X

GU C., 1999, Combinatorial Chemistry and High Throughput Screening, 2, 353, 10.2174/1386207302666220206123825

HALLIDAY R. C., 1997, European Journal of Drug Metabolism and Pharmacokinetics, 22, 291, 10.1007/BF03190959

HAWKINS D. R, 1999, Drug Discovery Today, 4, 466, 10.1016/S1359-6446(99)01401-4

10.1021/ac981991q

HERRERA A. M., 1990, Pharmaceutical Research, 7, 1077, 10.1023/A:1015955503708

HOLLENBERG P. F., 1772, Carcinogenesis, 9, 1763–

HOP C. E., 1998, Journal of Pharmaceutical Sciences, 87, 901, 10.1021/js970486q

HUUSKONEN J., 2000, European Journal of Medicinal Chemistry, 35, 1081, 10.1016/S0223-5234(00)01186-7

10.1021/js9803205

10.1016/S1359-6446(00)01559-2

JOHNSON D. L., 2000, Drug Metabolism Reviews, 32, 185

KANSY M., 1998, Journal of Medicinal Chemistry, 41, O10

KASUHARA H., 2001, Drug Discovery Today, 6, 150, 10.1016/S1359-6446(00)01632-9

KENNEDY T, 1997, Drug Discovery Today, 2, 436, 10.1016/S1359-6446(97)01099-4

KIM R. B, 2000, Current Opinions in Drug Discovery and Development, 3, 94

KLOPMAN G., 1999, Theoretical Chemistry Accounts, 102, 33, 10.1007/s002140050470

KOBAYASHI K., 1990, Journal of Biological Chemistry, 265, 7737, 10.1016/S0021-9258(19)38990-2

KOEHLER R. A., 1999, Journal of Medicinal Chemistry, 42, 4695, 10.1021/jm990312g

LEHMANN J. M., 1998, Journal of Clinical Investigation, 102, 023

LEWIS D. F., 1998, Xenobiotica, 28, 235, 10.1080/004982598239542

10.1080/004982597240497

LI, A. 1999, Higher throughput metabolism assays using human hepatocytes. Paper presented at the AAPS Annual Meeting, New Orleans, LA, Symposium Proceedings.

LI A. P., 1999, Chemko-Biological Interactions, 121, 17, 10.1016/S0009-2797(99)00088-5

LIN J. H., 1998, Clinical Pharmacokinetics, 35, 361, 10.2165/00003088-199835050-00003

10.1016/S0169-409X(96)00423-1

MADAN A., 1999, Drug Metabolism and Disposition, 27, 327

MCCARTHY S., 1996, Pharmacology Research, 13, S242

MICHNE W. F, 1996, Pharmaceutical News, 3, 19

MOODY G. C., 1999, Xenobiotica, 9, 53, 10.1080/004982599238812

10.1016/S0300-483X(00)00300-0

MULLINS M. E., 1998, Journal of American Medical Association, 280, 157, 10.1001/jama.280.2.157

NTAVIA M. A., 1996, Drug Discovery Today, 1, 179, 10.1016/1359-6446(96)10020-9

NIINUMA K., 1999, American Journal of Physiology, 276, G1153—G1164

NORDYKE A., 2000, Drug Metabolism Reviews, 32, 183

10.1021/js970439y

OBACH R. S., 1997, Journal of Pharmacology and Experimental Therapeutics, 283, 46

OUATT T. V., 1997, Rapid Communications in Mass Spectrometry, 11, 17, 10.1002/(SICI)1097-0231(19970115)11:1<17::AID-RCM812>3.0.CO;2-N

PACICI G. M., 1992, Clinical Pharmacokinetics, 23, 449, 10.2165/00003088-199223060-00005

PAGE M. J., 1999, Drug Discovery Today, 4, 55, 10.1016/S1359-6446(98)01291-4

PALM K., 1997, Pharmaceutical Research, 14, 568, 10.1023/A:1012188625088

PAN J., 2000, Drug Metabolism and Disposition, 28, 709

10.1046/j.1471-4159.1998.70051781.x

10.1023/A:1007537520620

10.1021/jm00004a004

PRENTIS R. A., 1988, British Journal of Clinical Pharmacology, 25, 387, 10.1111/j.1365-2125.1988.tb03318.x

ROBERTSON D. G., 2000, Current Opinions in Drug Discovery and Development, 3, 42

RODRIGUES A. D., 1997, Drug Metabolism and Disposition, 25, 1097

ROSENBERG S. H., 1993, Journal of Medicinal Chemistry, 36, 449, 10.1021/jm00056a005

RUELLE P., 1998, Journal of Pharmaceutical Sciences, 87, 998, 10.1021/js9702980

RYU D.-Y., 1996, Molecular Pharmacology, 50, 443

SADOWSKI J., 1998, Journal of Medicinal Chemistry, 41, 3325, 10.1021/jm9706776

10.1046/j.1432-1327.1998.2510252.x

SEGALL M. D., 1997, European Journal of Drug Metabolism and Pharmacokinetics, 22, 283, 10.1007/BF03190958

SHITARA Y., 2000, Drug Metabolism Reviews, 32, 194

SIMPSON H., 1998, Rapid Communications in Mass Spectrometry, 12, 75, 10.1002/(SICI)1097-0231(19980131)12:2<75::AID-RCM112>3.0.CO;2-C

SINKO P. J, 1999, Current Opinions in Drug Discovery and Development, 2, 42

SINKO P. J., 1996, Pharmaceutical Research, 13, 570, 10.1023/A:1016098121784

SMITH D. A, 1998, Biomedical Health Research, 25, 137

STEIN W. D., 1996, Biochemistry and Molecular Biology, 115, 307, 10.1016/S0305-0491(96)00177-0

10.1016/S0169-409X(96)00424-3

SUGIYAMA Y., 2000, Drug Metabolism Reviews, 32, 137

SWANN P. W., 1997, Journal of Pharmaceutical Sciences, 86, 596, 10.1021/js960359e

SZLARZ G. D., 1997, Journal of Computer Aided Molecular Design, 11, 265, 10.1023/A:1007956612081

TARBIT M. H., 1998, Current Opinion in Chemical Biology, 2, 411, 10.1016/S1367-5931(98)80017-3

TASKINEN J, 2000, Current Opinions in Drug Discovery and Development, 3, 102

TODD M. D., 1999, Current Opinions in Drug Discovery Development, 2, 58

TOMINAGA Y, 1999, Chemometrics and Intelligent Laboratory Systems, 49, 105, 10.1016/S0169-7439(99)00034-9

TROPSH A, 2000, Current Opinions in Drug Discovery and Development, 3, 310

VAN BREEMEN, R. B., Nixouc, D. and BOLTON, J. L.,, 1998, Drug Metabolism and Disposition, 26, 85

VAN DE WATERBEEMBD, H., CAMENISCH, G., FOLKERS, G. and RAEVSKY, O. A.,, 1996, Quantitative Structure Activity Relationships, 15, 480, 10.1002/qsar.19960150604

WALLACE R. W, 1997, Drug Discovery Today, 2, 557, 10.1016/S1359-6446(97)01117-3

10.1016/S1359-6446(98)01290-2

10.1016/S1359-6446(97)01163-X

WATT A. P., 2000, Drug Discovery Today, 5, 17, 10.1016/S1359-6446(99)01434-8

10.1021/ci980029a

WINIWARTER S., 1998, Journal of Medicinal Chemistry, 41, 4939, 10.1021/jm9810102

WOLF R. C., 1998, Journal of Pharmacy and Pharmacology, 50, 567, 10.1111/j.2042-7158.1998.tb06889.x

WYNALDA M. A., 1997, Drug Metabolism and Disposition, 25, 1211

YAMAZAKI M., 1996, Pharmaceutical Research, 13, 497, 10.1023/A:1016077517241

YIN H., 2000, Xenobiotica, 30, 141, 10.1080/004982500237749