High-throughput longitudinal electrophysiology screening of mature chamber-specific hiPSC-CMs using optical mapping
Tài liệu tham khảo
Zhang, 2009, Functional cardiomyocytes derived from human induced pluripotent stem cells, Circ. Res., 104, e30, 10.1161/CIRCRESAHA.108.192237
Thomson, 1998, Embryonic stem cell lines derived from human blastocysts, Science, 282, 1145, 10.1126/science.282.5391.1145
Takahashi, 2007, Induction of pluripotent stem cells from adult human fibroblasts by defined factors, Cell, 131, 861, 10.1016/j.cell.2007.11.019
Ahmed, 2020, A Brief Review of Current Maturation Methods for Human Induced Pluripotent Stem Cells-Derived Cardiomyocytes, Front. Cell Dev. Biol., 8, 178, 10.3389/fcell.2020.00178
Blinova, 2018, International Multisite Study of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Drug Proarrhythmic Potential Assessment, Cell Rep., 24, 3582, 10.1016/j.celrep.2018.08.079
da Rocha, 2020, Detection of Drug-Induced Torsades de Pointes Arrhythmia Mechanisms Using hiPSC-CM Syncytial Monolayers in a High-Throughput Screening Voltage Sensitive Dye Assay, Toxicol. Sci., 173, 402, 10.1093/toxsci/kfz235
Yang, 2022, Use of Human iPSC-CMs in Nonclinical Regulatory Studies for Cardiac Safety Assessment, Toxicol. Sci., 190, 117, 10.1093/toxsci/kfac095
Davis, 2021, In vitro model of ischemic heart failure using human induced pluripotent stem cell-derived cardiomyocytes, JCI Insight, 6, e134368, 10.1172/jci.insight.134368
Lan, 2013, Abnormal calcium handling properties underlie familial hypertrophic cardiomyopathy pathology in patient-specific induced pluripotent stem cells, Cell Stem Cell, 12, 101, 10.1016/j.stem.2012.10.010
Feng, 2021, Long QT Syndrome KCNH2 Variant Induces hERG1a/1b Subunit Imbalance in Patient-Specific Induced Pluripotent Stem Cell-Derived Cardiomyocytes, Circ. Arrhythm. Electrophysiol., 14, e009343, 10.1161/CIRCEP.120.009343
Eisen, 2019, Electrophysiological abnormalities in induced pluripotent stem cell-derived cardiomyocytes generated from Duchenne muscular dystrophy patients, J. Cell Mol. Med., 23, 2125, 10.1111/jcmm.14124
Kawamura, 2012, Feasibility, safety, and therapeutic efficacy of human induced pluripotent stem cell-derived cardiomyocyte sheets in a porcine ischemic cardiomyopathy model, Circulation, 126, S29, 10.1161/CIRCULATIONAHA.111.084343
Liew, 2020, Mending a broken heart: current strategies and limitations of cell-based therapy, Stem Cell Res. Ther., 11, 138, 10.1186/s13287-020-01648-0
Blinova, 2019, Clinical Trial in a Dish: Personalized Stem Cell–Derived Cardiomyocyte Assay Compared With Clinical Trial Results for Two QT-Prolonging Drugs, Clin. Transl. Sci., 12, 687, 10.1111/cts.12674
Strauss, 2017, Clinical Trials in a Dish, Trends Pharmacol. Sci., 38, 4, 10.1016/j.tips.2016.10.009
Ma, 2011, High purity human-induced pluripotent stem cell-derived cardiomyocytes: electrophysiological properties of action potentials and ionic currents, Am. J. Physiol. Heart Circ. Physiol., 301, H2006, 10.1152/ajpheart.00694.2011
Cyganek, 2018, Deep phenotyping of human induced pluripotent stem cell-derived atrial and ventricular cardiomyocytes, JCI Insight, 3, e99941, 10.1172/jci.insight.99941
Herron, 2016, Extracellular Matrix-Mediated Maturation of Human Pluripotent Stem Cell-Derived Cardiac Monolayer Structure and Electrophysiological Function, Circ. Arrhythm. Electrophysiol., 9, e003638, 10.1161/CIRCEP.113.003638
Blinova, 2017, Comprehensive Translational Assessment of Human-Induced Pluripotent Stem Cell Derived Cardiomyocytes for Evaluating Drug-Induced Arrhythmias, Toxicol. Sci., 155, 234, 10.1093/toxsci/kfw200
Block, 2020, Human perinatal stem cell derived extracellular matrix enables rapid maturation of hiPSC-CM structural and functional phenotypes, Sci. Rep., 10, 19071, 10.1038/s41598-020-76052-y
Smith, 2020, NanoMEA: A Tool for High-Throughput, Electrophysiological Phenotyping of Patterned Excitable Cells, Nano Lett., 20, 1561, 10.1021/acs.nanolett.9b04152
Feaster, 2015, Matrigel Mattress: A Method for the Generation of Single Contracting Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes, Circ. Res., 117, 995, 10.1161/CIRCRESAHA.115.307580
Dhahri, 2022, In Vitro Matured Human Pluripotent Stem Cell–Derived Cardiomyocytes Form Grafts With Enhanced Structure and Function in Injured Hearts, Circulation, 145, 1412, 10.1161/CIRCULATIONAHA.121.053563
Kamakura, 2013, Ultrastructural Maturation of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes in a Long-Term Culture, Circ. J., 77, 1307, 10.1253/circj.CJ-12-0987
Lundy, 2013, Structural and functional maturation of cardiomyocytes derived from human pluripotent stem cells, Stem Cell. Dev., 22, 1991, 10.1089/scd.2012.0490
Lewandowski, 2018, The impact of in vitro cell culture duration on the maturation of human cardiomyocytes derived from induced pluripotent stem cells of myogenic origin, Cell Transplant., 27, 1047, 10.1177/0963689718779346
da Rocha, 2017, hiPSC-CM Monolayer Maturation State Determines Drug Responsiveness in High Throughput Pro-Arrhythmia Screen, Sci. Rep., 7, 13834, 10.1038/s41598-017-13590-y
Almeida, 2021, Human Extracellular-Matrix Functionalization of 3D hiPSC-Based Cardiac Tissues Improves Cardiomyocyte Maturation, ACS Appl. Bio Mater., 4, 1888, 10.1021/acsabm.0c01490
Ronaldson-Bouchard, 2018, Advanced maturation of human cardiac tissue grown from pluripotent stem cells, Nature, 556, 239, 10.1038/s41586-018-0016-3
Nunes, 2013, Biowire: a platform for maturation of human pluripotent stem cell-derived cardiomyocytes, Nat. Methods, 10, 781, 10.1038/nmeth.2524
Herron, 2012, Optical imaging of voltage and calcium in cardiac cells & tissues, Circ. Res., 110, 609, 10.1161/CIRCRESAHA.111.247494
Gintant, 2020, Repolarization studies using human stem cell-derived cardiomyocytes: Validation studies and best practice recommendations, Regul. Toxicol. Pharmacol., 117, 104756, 10.1016/j.yrtph.2020.104756
Russell, 1959
Bers, 2002, Cardiac excitation–contraction coupling, Nature, 415, 198, 10.1038/415198a
Veerman, 2015, Immaturity of Human Stem-Cell-Derived Cardiomyocytes in Culture: Fatal Flaw or Soluble Problem?, Stem Cell. Dev., 24, 1035, 10.1089/scd.2014.0533
Garg, 2018, Human Induced Pluripotent Stem Cell–Derived Cardiomyocytes as Models for Cardiac Channelopathies, Circ. Res., 123, 224, 10.1161/CIRCRESAHA.118.311209
Inoue, 1991, Antiarrhythmic drugs preferentially produce conduction block at the area of slow conduction in the re-entrant circuit of canine atrial flutter: comparative study of disopyramide, flecainide, and E-4031, Cardiovasc. Res., 25, 223, 10.1093/cvr/25.3.223
Doss, 2012, Maximum Diastolic Potential of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Depends Critically on IKr, PLoS One, 7, e40288, 10.1371/journal.pone.0040288
Yu, 2009, Human induced pluripotent stem cells free of vector and transgene sequences, Science (New York, N.Y.), 324, 797, 10.1126/science.1172482
Reiser, 2001, Human cardiac myosin heavy chain isoforms in fetal and failing adult atria and ventricles, Am. J. Physiol. Heart Circ. Physiol., 280, H1814, 10.1152/ajpheart.2001.280.4.H1814
Herron, 2007, Calcium-independent negative inotropy by beta-myosin heavy chain gene transfer in cardiac myocytes, Circ. Res., 100, 1182, 10.1161/01.RES.0000264102.00706.4e
Nielsen, 2018, Biobank-driven genomic discovery yields new insight into atrial fibrillation biology, Nat. Genet., 50, 1234, 10.1038/s41588-018-0171-3
Fedida, 2007, Vernakalant (RSD1235): a novel, atrial-selective antifibrillatory agent, Expet Opin. Invest. Drugs, 16, 519, 10.1517/13543784.16.4.519
Roy, 2008, Vernakalant Hydrochloride for Rapid Conversion of Atrial Fibrillation, Circulation, 117, 1518, 10.1161/CIRCULATIONAHA.107.723866
Chen, 2013, Ultrasensitive fluorescent proteins for imaging neuronal activity, Nature, 499, 295, 10.1038/nature12354
Nakai, 2001, A high signal-to-noise Ca(2+) probe composed of a single green fluorescent protein, Nat. Biotechnol., 19, 137, 10.1038/84397
Statzer, 2020, The extracellular matrix phenome across species, Matrix Biol., 8, 100039, 10.1016/j.mbplus.2020.100039
Sainio, 2020, Extracellular matrix-cell interactions: Focus on therapeutic applications, Cell. Signal., 66, 109487, 10.1016/j.cellsig.2019.109487
Saleem, 2020, Blinded, Multicenter Evaluation of Drug-induced Changes in Contractility Using Human-induced Pluripotent Stem Cell-derived Cardiomyocytes, Toxicol. Sci., 176, 103, 10.1093/toxsci/kfaa058
Goldfracht, 2020, Generating ring-shaped engineered heart tissues from ventricular and atrial human pluripotent stem cell-derived cardiomyocytes, Nat. Commun., 11, 75, 10.1038/s41467-019-13868-x
Wettwer, 2013, The new antiarrhythmic drug vernakalant: ex vivo study of human atrial tissue from sinus rhythm and chronic atrial fibrillation, Cardiovasc. Res., 98, 145, 10.1093/cvr/cvt006
Qu, 2017, Action Potential Recording and Pro-arrhythmia Risk Analysis in Human Ventricular Trabeculae, Front. Physiol., 8, 1109, 10.3389/fphys.2017.01109
Jiang, 2018, An Ultrasensitive Calcium Reporter System via CRISPR-Cas9-Mediated Genome Editing in Human Pluripotent Stem Cells, iScience, 9, 27, 10.1016/j.isci.2018.10.007
Acharya, 2022, Live-Cell Imaging of the Contractile Velocity and Transient Intracellular Ca(2+) Fluctuations in Human Stem Cell-Derived Cardiomyocytes, Cells, 11, 1280, 10.3390/cells11081280
Shinnawi, 2015, Monitoring Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes with Genetically Encoded Calcium and Voltage Fluorescent Reporters, Stem Cell Rep., 5, 582, 10.1016/j.stemcr.2015.08.009
Lou, 2012, Remodeling of calcium handling in human heart failure, Adv. Exp. Med. Biol., 740, 1145, 10.1007/978-94-007-2888-2_52
Morgan, 1990, Abnormal intracellular calcium handling, a major cause of systolic and diastolic dysfunction in ventricular myocardium from patients with heart failure, Circulation, 81
Bedada, 2014, Acquisition of a quantitative, stoichiometrically conserved ratiometric marker of maturation status in stem cell-derived cardiac myocytes, Stem Cell Rep., 3, 594, 10.1016/j.stemcr.2014.07.012
Gu, 2021, Recent Advances in Maturation of Pluripotent Stem Cell-Derived Cardiomyocytes Promoted by Mechanical Stretch, Med. Sci. Mon. Int. Med. J. Exp. Clin. Res., 27, e931063
Tzatzalos, 2016, Engineered heart tissues and induced pluripotent stem cells: Macro- and microstructures for disease modeling, drug screening, and translational studies, Adv. Drug Deliv. Rev., 96, 234, 10.1016/j.addr.2015.09.010
Weinberger, 2017, Engineering Cardiac Muscle Tissue, Circ. Res., 120, 1487, 10.1161/CIRCRESAHA.117.310738
Chen, 2007, Extracellular matrix made by bone marrow cells facilitates expansion of marrow-derived mesenchymal progenitor cells and prevents their differentiation into osteoblasts, J. Bone Miner. Res., 22, 1943, 10.1359/jbmr.070725
Marinkovic, 2016, One size does not fit all: developing a cell-specific niche for in vitro study of cell behavior, Matrix Biol., 52–54, 426, 10.1016/j.matbio.2016.01.004
Lian, 2012, Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling, Proc. Natl. Acad. Sci. USA, 109, E1848, 10.1073/pnas.1200250109
Monteiro da Rocha, 2016, Deficient cMyBP-C protein expression during cardiomyocyte differentiation underlies human hypertrophic cardiomyopathy cellular phenotypes in disease specific human ES cell derived cardiomyocytes, J. Mol. Cell. Cardiol., 99, 197, 10.1016/j.yjmcc.2016.09.004
Zhang, 2019, Functional cardiac fibroblasts derived from human pluripotent stem cells via second heart field progenitors, Nat. Commun., 10, 2238, 10.1038/s41467-019-09831-5
Lee, 2012, Simultaneous voltage and calcium mapping of genetically purified human induced pluripotent stem cell-derived cardiac myocyte monolayers, Circ. Res., 110, 1556, 10.1161/CIRCRESAHA.111.262535