High dietary fructose promotes hepatocellular carcinoma progression by enhancing O-GlcNAcylation via microbiota-derived acetate
Tài liệu tham khảo
Ter Horst, 2017, Fructose consumption, lipogenesis, and non-alcoholic fatty liver disease, Nutrients, 9, 981, 10.3390/nu9090981
Febbraio, 2021, “Sweet death”: fructose as a metabolic toxin that targets the gut-liver axis, Cell Metab., 33, 2316, 10.1016/j.cmet.2021.09.004
Carreño, 2021, Dietary fructose promotes prostate cancer growth, Cancer Res., 81, 2824, 10.1158/0008-5472.CAN-19-0456
Chen, 2022, ATF4-dependent fructolysis fuels growth of glioblastoma multiforme, Nat. Commun., 13, 6108, 10.1038/s41467-022-33859-9
Chen, 2020, GLUT5-mediated fructose utilization drives lung cancer growth by stimulating fatty acid synthesis and AMPK/mTORC1 signaling, JCI Insight, 5, 10.1172/jci.insight.131596
Jeong, 2021, High fructose drives the serine synthesis pathway in acute myeloid leukemic cells, Cell Metab., 33, 145, 10.1016/j.cmet.2020.12.005
Goncalves, 2019, High-fructose corn syrup enhances intestinal tumor growth in mice, Science, 363, 1345, 10.1126/science.aat8515
Liu, 2010, Fructose induces transketolase flux to promote pancreatic cancer growth, Cancer Res., 70, 6368, 10.1158/0008-5472.CAN-09-4615
Foerster, 2022, Emerging immunotherapy for HCC: a guide for hepatologists, Hepatology, 75, 1604, 10.1002/hep.32447
Stepien, 2016, Consumption of soft drinks and juices and risk of liver and biliary tract cancers in a European cohort, Eur. J. Nutr., 55, 7, 10.1007/s00394-014-0818-5
Healy, 2015, Dietary effects on liver tumor burden in mice treated with the hepatocellular carcinogen diethylnitrosamine, J. Hepatol., 62, 599, 10.1016/j.jhep.2014.10.024
Kumamoto, 2013, Dietary fructose enhances the incidence of precancerous hepatocytes induced by administration of diethylnitrosamine in rat, Eur. J. Med. Res., 18, 54, 10.1186/2047-783X-18-54
Todoric, 2020, Fructose stimulated de novo lipogenesis is promoted by inflammation, Nat. Metab., 2, 1034, 10.1038/s42255-020-0261-2
Dewdney, 2020, The effects of fructose and metabolic inhibition on hepatocellular carcinoma, Sci. Rep., 10, 16769, 10.1038/s41598-020-73653-5
Tao, 2015, Aldolase B inhibits metastasis through Ten-Eleven Translocation 1 and serves as a prognostic biomarker in hepatocellular carcinoma, Mol. Cancer, 14, 170, 10.1186/s12943-015-0437-7
Tee, 2022, Ketohexokinase-mediated fructose metabolism is lost in hepatocellular carcinoma and can be leveraged for metabolic imaging, Sci. Adv., 8, eabm7985, 10.1126/sciadv.abm7985
Decourcelle, 2020, O-GlcNAcylation links nutrition to the epigenetic downregulation of UNC5A during colon carcinogenesis, Cancers (Basel), 12, 3168, 10.3390/cancers12113168
Wong, 2020, The nutrient sensor OGT regulates Hipk stability and tumorigenic-like activities in Drosophila, Proc. Natl. Acad. Sci. USA, 117, 2004, 10.1073/pnas.1912894117
Jiang, 2019, Fatty acid-induced CD36 expression via O-GlcNAcylation drives gastric cancer metastasis, Theranostics, 9, 5359, 10.7150/thno.34024
Lam, 2021, The hexosamine biosynthetic pathway and cancer: current knowledge and future therapeutic strategies, Cancer Lett., 503, 11, 10.1016/j.canlet.2021.01.010
Parker, 2021, O-GlcNAcylation and O-GlcNAc cycling regulate gene transcription: emerging roles in cancer, Cancers (Basel), 13, 10.3390/cancers13071666
Yang, 2017, Protein O-GlcNAcylation: emerging mechanisms and functions, Nat. Rev. Mol. Cell Biol., 18, 452, 10.1038/nrm.2017.22
Hu, 2021, Hexosamine biosynthetic pathway promotes the antiviral activity of SAMHD1 by enhancing O-GlcNAc transferase-mediated protein O-GlcNAcylation, Theranostics, 11, 805, 10.7150/thno.50230
Xu, 2017, O-GlcNAc transferase promotes fatty liver-associated liver cancer through inducing palmitic acid and activating endoplasmic reticulum stress, J. Hepatol., 67, 310, 10.1016/j.jhep.2017.03.017
Ciraku, 2022, O-GlcNAcylation regulation of cellular signaling in cancer, Cell. Signal., 90, 110201, 10.1016/j.cellsig.2021.110201
Akella, 2019, Fueling the fire: emerging role of the hexosamine biosynthetic pathway in cancer, BMC Biol., 17, 52, 10.1186/s12915-019-0671-3
Li, 2016, A splicing switch from ketohexokinase-C to ketohexokinase-A drives hepatocellular carcinoma formation, Nat. Cell Biol., 18, 561, 10.1038/ncb3338
Zhao, 2020, Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate, Nature, 579, 586, 10.1038/s41586-020-2101-7
Mashimo, 2014, Acetate is a bioenergetic substrate for human glioblastoma and brain metastases, Cell, 159, 1603, 10.1016/j.cell.2014.11.025
Schug, 2016, The metabolic fate of acetate in cancer, Nat. Rev. Cancer, 16, 708, 10.1038/nrc.2016.87
Huang, 2003, De novo synthesis of pyrimidine nucleotides; emerging interfaces with signal transduction pathways, Cell. Mol. Life Sci., 60, 321, 10.1007/s000180300027
Chiaradonna, 2018, The nutrient-sensing hexosamine biosynthetic pathway as the hub of cancer metabolic rewiring, Cells, 7, 10.3390/cells7060053
Wang, 2011, Zinc finger protein ZBTB20 expression is increased in hepatocellular carcinoma and associated with poor prognosis, BMC Cancer, 11, 271, 10.1186/1471-2407-11-271
Bai, 2009, Capn4 overexpression underlies tumor invasion and metastasis after liver transplantation for hepatocellular carcinoma, Hepatology, 49, 460, 10.1002/hep.22638
Dai, 2014, Capn4 contributes to tumour growth and metastasis of hepatocellular carcinoma by activation of the FAK-Src signalling pathways, J. Pathol., 234, 316, 10.1002/path.4395
Liu, 2019, METTL13 methylation of eEF1A increases translational output to promote tumorigenesis, Cell, 176, 491, 10.1016/j.cell.2018.11.038
Fang, 2023, Fructose metabolism in tumor endothelial cells promotes angiogenesis by activating AMPK signaling and mitochondrial respiration, Cancer Res., 83, 1249, 10.1158/0008-5472.CAN-22-1844
Caliceti, 2017, Fructose intake, serum uric acid, and cardiometabolic disorders: a critical review, Nutrients, 9, 10.3390/nu9040395
Jang, 2018, The small intestine converts dietary fructose into glucose and organic acids, Cell Metab., 27, 351, 10.1016/j.cmet.2017.12.016
Martínez-Reyes, 2021, Cancer metabolism: looking forward, Nat. Rev. Cancer, 21, 669, 10.1038/s41568-021-00378-6
Comerford, 2014, Acetate dependence of tumors, Cell, 159, 1591, 10.1016/j.cell.2014.11.020
Schug, 2015, Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress, Cancer Cell, 27, 57, 10.1016/j.ccell.2014.12.002
Björnson, 2015, Stratification of hepatocellular carcinoma patients based on acetate utilization, Cell Rep., 13, 2014, 10.1016/j.celrep.2015.10.045
Bott, 2015, Oncogenic Myc induces expression of glutamine synthetase through promoter demethylation, Cell Metab., 22, 1068, 10.1016/j.cmet.2015.09.025
Cox, 2016, Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growth, Nat. Cell Biol., 18, 886, 10.1038/ncb3389
Lachenmayer, 2012, Wnt-pathway activation in two molecular classes of hepatocellular carcinoma and experimental modulation by sorafenib, Clin. Cancer Res., 18, 4997, 10.1158/1078-0432.CCR-11-2322
Yun, 2009, The importance of acetyl coenzyme A synthetase for 11C-acetate uptake and cell survival in hepatocellular carcinoma, J. Nucl. Med., 50, 1222, 10.2967/jnumed.109.062703
Jeon, 2018, Regulation of acetate utilization by monocarboxylate transporter 1 (MCT1) in hepatocellular carcinoma (HCC), Oncol. Res., 26, 71, 10.3727/096504017X14902648894463
Pelletier, 2018, Ribosome biogenesis in cancer: new players and therapeutic avenues, Nat. Rev. Cancer, 18, 51, 10.1038/nrc.2017.104
Jang, 2015, O-GlcNAcylation of eIF2alpha regulates the phospho-eIF2alpha-mediated ER stress response, Biochim. Biophys. Acta, 1853, 1860, 10.1016/j.bbamcr.2015.04.017
Cristiano, 2022, The pseudogenes of eukaryotic translation elongation factors (EEFs): role in cancer and other human diseases, Genes Dis., 9, 941, 10.1016/j.gendis.2021.03.009
Chen, 2018, eEF1A1 overexpression enhances tumor progression and indicates poor prognosis in hepatocellular carcinoma, Transl. Oncol., 11, 125, 10.1016/j.tranon.2017.11.001
Perrone, 2021, Targeted delivery of siRNAs against hepatocellular carcinoma-related genes by a galactosylated polyaspartamide copolymer, J. Control. Release, 330, 1132, 10.1016/j.jconrel.2020.11.020
Jiang, 2023, Dynamic regulation of eEF1A1 acetylation affects colorectal carcinogenesis, Biol. Chem., 404, 585, 10.1515/hsz-2022-0180
Papanicolas, 2018, Not just antibiotics: is cancer chemotherapy driving antimicrobial resistance?, Trends Microbiol., 26, 393, 10.1016/j.tim.2017.10.009
Sepich-Poore, 2021, The microbiome and human cancer, Science, 371, 10.1126/science.abc4552
Shen, 2022, Abnormal bile acid-microbiota crosstalk promotes the development of hepatocellular carcinoma, Hepatol. Int., 16, 396, 10.1007/s12072-022-10299-7
Moya, 2019, Peritumoral activation of the Hippo pathway effectors YAP and TAZ suppresses liver cancer in mice, Science, 366, 1029, 10.1126/science.aaw9886
Shen, 2021, Serine metabolism antagonizes antiviral innate immunity by preventing ATP6V0d2-mediated YAP lysosomal degradation, Cell Metab., 33, 971, 10.1016/j.cmet.2021.03.006
Tian, 2022, Precise metabolomics reveals a diversity of aging-associated metabolic features, Small Methods, 6, e2200130, 10.1002/smtd.202200130
Zhou, 2023, O-GlcNAcylation of SPOP promotes carcinogenesis in hepatocellular carcinoma, Oncogene, 42, 725, 10.1038/s41388-022-02589-z