High‐Resolution B‐Mode Ultrasound Reading Methods in the Atherosclerosis Risk in Communities (ARIC) Cohort

Journal of Neuroimaging - Tập 1 Số 4 - Trang 168-172 - 1991
Ward A. Riley1, Ralph W. Barnes1, M. Gene Bond2, Greg Evans3, Lloyd E. Chambless4, Gerardo Heiss5
1Department of Neurology Bowman Gray School of Medicine AUTREC, Inc Winston-Salem, NC
2Division of Vascular Ultrasound Research and the Department of Neurobiology and Anatomy Bowman Gray School of Medicine
3Department of Public Health Sciences Bowman Gray School of Medicine
4Department of Biostatistics, School of Public Health, University of North Carolina, Chapel Hill, NC
5Department of Epidemiology, School of Public Health, University of North Carolina

Tóm tắt

To measure the association of cardiovascular disease risk factors with carotid artery diameter and thickness of the intima and media in the general population, standardized ultrasound scanning and reading protocols were performed on 15,800 individuals in the multicenter Atherosclerosis Risk in Communities (ARIC) Study. In a randomly selected subset of 855 participants, the mean artery diameter, minimum lumen diameter, and maximum near‐and far‐wall thicknesses were measured at a core laboratory from B‐mode image recordings of the common carotid, bifurcation, and internal carotid arteries to determine both within‐reader and between‐reader variability. Measurements associated with the wall thickness are sensitive indicators of reader reproducibility, with between‐reader reliability coefficients ranging from 0. 78 to 0.93 and coefficients of variation ranging from 13.1 to 18.3%. The percent of paired readings in the three carotid segments for which the absolute difference of the far‐wall thickness measured by different readers was no greater than one image pixel (0.067 mm) was 58% (common carotid), 53% (internal carotid), and 42% (bifurcation). Highly reproducible measurements of carotid artery dimensions can be achieved with standardized training and performance of ultrasound scanning and reading protocols.

Từ khóa


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