High Intensity Physical Exercise before the Brain Ischemia Promotes Increase in Brain Injury

Gomes, 2005, 1 Liberato, 2016, 1 Hankey, 2016, Stroke, 1 Meschia, 2014, Guidelines for the primary prevention of stroke, Stroke, 45, 3754, 10.1161/STR.0000000000000046 Siegler, 2013, Identification of modifiable and non-modifiable risk factors for neurological deterioration following acute ischemic stroke, J Stroke Cerebrovasc Dis, 22, 207, 10.1016/j.jstrokecerebrovasdis.2012.11.006 Almeida, 2013 Teixeira-Coelho, 2017, Effects of manipulating the duration and intensity of aerobic training sessions on the physical performance of rats, Plos One, 12, 1, 10.1371/journal.pone.0183763 Kemi, 2005, Moderate vs. high exercise intensity: differential effects on aerobic fitness, cardiomyocyte contractility, and endothelial function, Cardiovasc Research, 67, 161, 10.1016/j.cardiores.2005.03.010 De Lade, 2018, Effects of moderate intensity endurance training vs. high intensity interval training on weight gain, cardiorespiratory capacity, and metabolic profile in postnatal overfed rats, Diabetol Metab Syndr, 10, 1 Rezaei, 2018, High intensity exercise preconditioning provides differential protection against brain injury following experimental stroke, Life Sci, 15, 30, 10.1016/j.lfs.2018.03.007 Rodrigues, 2016, Effects of high intensity resistance exercise in rats that received dexamethasone, Rev Bras Med Esporte [online], 22, 211, 10.1590/1517-869220162203148503 Ding, 2004, Motor balance and coordination functional outcome in rat with cerebral artery occlusion training enhances transient middle, Neuroscience, 123, 667, 10.1016/j.neuroscience.2003.08.031 Zhang, 2012, Very early-initiated physical rehabilitation protects against ischemic brain injury, Front Biosci, 4, 2476 Lucas, 2015, High-intensity interval exercise and cerebrovascular health: curiosity, cause, and consequence, Blood Flow Metab, 35, 902, 10.1038/jcbfm.2015.49 Damázio, 2014, Effects of exercise prior or after ischemia on the density of neurons and astrocytes in the brain of rats, Am J Neurosci, 5, 18 Schjerve, 2008, Both aerobic endurance and strength training programmes improve cardiovascular health in obese adults, Clin Sci (Lond), 115, 283, 10.1042/CS20070332 Mill, 2001, Cardiac hypertrophy, Rev Bras Hipertens, 8, 63 Telles, 2014, Prenatal curcumin administration reverses behavioral and neurochemical effects and decreases iNOS and COX-2 expressions in ischemic rat pups, Int J BrainSci, 1, 1 Lee, 2014, Comparison of surgical methods of transient middle cerebral artery occlusion between rats and mice, J Vet Med Sci, 76, 1555, 10.1292/jvms.14-0258 Farkas, 2007, Permanent, bilateral common carotid artery occlusion in the rat: a model for chronic cerebral hypoperfusion-related neurodegenerative diseases, Brain Res Rev, 54, 162, 10.1016/j.brainresrev.2007.01.003 Damázio, 2019, Efeitos de treinamento de alta intensidade sobre o desempenho motor e hipertrofia cardíaca de ratos que sofreram isquemia cerebral pós treinamento, Revista Brasileira de Prescrição e Fisiologia do Exercício, 13, 282 Damy, 2010, Aspectos fundamentais da experimentação animal - aplicações em cirurgia experimental, Rev. Assoc. Med. Bras., 56, 1, 10.1590/S0104-42302010000100024 Heck, 2011, 154 Hornberger, 2004, Physiological hypertrophy of the FHL muscle following 8 weeks of progressive resistance exercise in the rat, Can J Appl Physiol Champaign, 29, 16, 10.1139/h04-002 Peixinho-Penha, 2012, A strength exercise program in rats with epilepsy is protective against seizures, Epilepsy Behav, 25, 323, 10.1016/j.yebeh.2012.08.011 Cassilhas, 2013, Animal model for progressive resistance exercise: a detailed description of model and its implications for basic research in exercise, Motriz, 19, 178 Lana, 2006, Influence of low and high intensity physical exercise on hypernociception threshold and other parameters of rats, Rev Bras Med Esporte, 12, 248, 10.1590/S1517-86922006000500005 Gonçalves, 2018, Environmental enrichment cognitive neuroprotection in an experimental model of cerebral ischemia: biochemical and molecular aspects, Behav Brain Res, 348, 171, 10.1016/j.bbr.2018.04.023 Tardini, 2003, Avaliação de dois modelos experimentais de isquemia e reperfusão cerebral em ratos com oclusão temporária carotídea associada ou não à oclusão vertebral, Acta Cirúrgica Brasileira, 18, 502, 10.1590/S0102-86502003000600004 Modo, 2000, Neurological sequelae and long-term behavioural assessment of rats with transient middle cerebral artery occlusion, J Neurosci Methods, 194, 99, 10.1016/S0165-0270(00)00329-0 Scorza, 2005, Estudo qualitativo da formação hipocampal de animais hipertensos com epilepsia, Arquivo Neuropsiquiatria, 63, 283, 10.1590/S0004-282X2005000200015 Damázio, 2013, 59 Monteiro, 2004, Avaliação das alterações morfológicas cardíacas secundárias ao enfisema pulmonar: estudo experimental em ratos, Revista Brasileira Cirurgia Cardiovascular, 19, 341 Junqueira, 2016, Efeitos do Hormônio do Crescimento na Remodelação Cardíaca Durante Treinamento Resistido em Ratos, Arq Bras Cardiol, 106, 18 Canakc, 2016, Histopathologic comparison of dexmedetomidine's and thiopental's cerebral protective effects on focal cerebral ischemia in rats, Rev Bras Anestesiol, 66, 583, 10.1016/j.bjan.2015.12.006 Parkkinen, 2013, Gait impairment in a rat model of focal cerebral ischemia, Stroke Res Treat, 1 Barbosa, 2018, Strength training protocols in hemiparetic individuals post stroke: a systematic review, Fisioter Mov, 31, 10.1590/1980-5918.031.ao27 Pianta, 2019, A short bout of exercise prior to stroke improves functional outcomes by enhancing angiogenesis, Neuromolecular Med, 21, 517, 10.1007/s12017-019-08533-x Arrick, 2014, Vigorous exercise training improves reactivity of cerebral arterioles and reduces brain injury following transient focal ischemia, Microcirculation, 21, 516, 10.1111/micc.12127 Woitke, 2017, Adult hippocampal neurogenesis poststroke: more new granule cells but aberrant morphology and impaired spatial memory, PLoS One, 12, 10.1371/journal.pone.0183463