High B‐value apparent diffusion‐weighted images from CURVE‐ball DTI

Journal of Magnetic Resonance Imaging - Tập 30 Số 1 - Trang 243-248 - 2009
Sharon Peled1,2, Stephen Whalen3, Ferenc A. Jólesz1,2, Alexandra J. Golby1,3
1Harvard Medical School, Boston, Massachusetts
2Radiology Department, Brigham and Women’s Hospital, Boston, Massachusetts
3Neurosurgery Department, Brigham and Women's Hospital, Boston, Massachusetts

Tóm tắt

AbstractPurposeTo investigate the utility of a proposed clinical diffusion imaging scheme for rapidly generating multipleb‐value diffusion contrast in brain magnetic resonance imaging (MRI) with high signal‐to‐noise ratio (SNR).Materials and MethodsOur strategy for efficient image acquisition relies on the invariance property of the diffusion tensor eigenvectors tob‐value. A simple addition to the conventional diffusion tensor MR imaging (DTI) data acquisition scheme used for tractography yields diffusion‐weighted images at twice and three times the conventionalb‐value. An example from a neurosurgical brain tumor is shown. Apparent diffusion‐weighted (ADW) images were calculated forb‐values 800, 1600, and 2400 s/mm2, and a map of excess diffusive kurtosis was computed from the three ADWs.ResultsHighb‐value ADW images demonstrated decreased contrast between normal gray and white matter, while the heterogeneity and contrast of the lesion was emphasized relative to conventionalb‐value data. Kurtosis maps indicated the deviation from Gaussian diffusive behavior.ConclusionDTI data with multipleb‐values and good SNR can be acquired in clinically reasonable times. Highb‐value ADW images show increased contrast and add information to conventional DWI. Ambiguity in conventionalb‐value images over whether hyperintense signal results from abnormally low diffusion, or abnormally long T2, is better resolved in highb‐value images. J. Magn. Reson. Imaging 2009;30:243–248. © 2009 Wiley‐Liss, Inc.

Từ khóa


Tài liệu tham khảo

Callaghan PT, 1991, Principles of nuclear magnetic resonance microscopy, 337, 10.1093/oso/9780198539445.001.0001

10.1002/mrm.1910140218

10.1148/radiology.210.1.r99ja02155

Tha KK, 2005, Early detection of global cerebral anoxia: improved accuracy by high‐b‐value diffusion‐weighted imaging with long echo time, AJNR Am J Neuroradiol, 26, 1487

Kim HJ, 2005, High‐b‐value diffusion‐weighted MR imaging of hyperacute ischemic stroke at 1.5T, AJNR Am J Neuroradiol, 26, 208

10.1111/j.1552-6569.2008.00263.x

10.3174/ajnr.A0842

10.1016/S1053-8119(03)00342-2

Usiskin SI, 2007, Progressive multifocal leukoencephalopathy: serial high‐b‐value diffusion‐weighted MR imaging and apparent diffusion coefficient measurements to assess response to highly active antiretroviral therapy, AJNR Am J Neuroradiol, 28, 285

10.1006/jmrb.1994.1037

10.1002/mrm.20642

10.1016/j.neuroimage.2007.02.050

10.1148/radiology.201.3.8939209

10.1002/mrm.1910350319

10.1002/mrm.20508

10.1148/radiology.219.3.r01jn02842

10.1002/mrm.10308

DeLano MC, 2000, High‐b‐value diffusion‐weighted MR imaging of adult brain: image contrast and apparent diffusion coefficient map features, AJNR Am J Neuroradiol, 21, 1830

10.1002/jmri.20789

10.1109/TMI.2007.906787

Thông tin
Thông tin xuất bản

Journal of Magnetic Resonance Imaging

Tập 30 Số 1

243-248

Thông tin tác giả