Heterogeneity of bone metastases as an important prognostic factor in patients affected by oestrogen receptor-positive breast cancer. The role of combined [18F]Fluoroestradiol PET/CT and [18F]Fluorodeoxyglucose PET/CT

Gianluca Bottoni1, Arnoldo Piccardo1, Francesco Fiz1, Giacomo Siri2, Federica Matteucci3, Andrea Rocca4, Oriana Nanni5, Manuela Monti5, Etienne Brain6, Jean Louis Alberini7, Bassam Dib8, Gian Mauro Sacchetti8, Chiara Saggia9, Valentina Rossi9, Nadia Harbeck10, Rachel Wuerstlein10, Tom Degenhardt10, Andrea DeCensi11, Gian Andrea Rollandi12, Alessandra Gennari13
1Department of Nuclear Medicine, E.O. “Ospedali Galliera”, Genoa, Italy
2Scientific Directorate, E.O. “Ospedali Galliera”, Genoa, Italy
3Nuclear Medicine Unit Istituto Scientifico Romagnolo per lo studio e la cura dei tumori, IRST, Meldola, Italy
4Medical Oncology Unit Istituto Scientifico Romagnolo per lo studio e la cura dei tumori, IRST, Meldola, Italy
5Biostatistics and Clinical Trials Unit, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST), Meldola, Italy
6Department of Clinical Research & Medical Oncology, Institut Curie (Hôpital René Huguenin), St Cloud, France
7Nuclear Medicine, Department Centre Georges-François Leclerc, 1 rue du Pr Marion, 21079 Dijon Cedex, France
8Nuclear Medicine Unit, AOU Maggiore della Carità, Novara, Italy
9Oncology Unit, AOU Maggiore della Carità, Novara, Italy
10Breast Centre, Department of Obstetrics and Gynaecology, University Hospital of Munich, Ludwig-Maximilians-University (LMU), Munich, Germany
11Department of Oncology, E.O. “Ospedali Galliera”, Genoa, Italy
12Department of Radiology, E.O. Ospedali Galliera, Genoa, Italy
13Department of Translational Oncology, University of Eastern Piedmont, Novara, Italy

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