Heterocycle-peptide hybrid compounds. Aminotriazole-containing agonists of the thrombin receptor (PAR-1)

Vu, 1991, Cell, 64, 1057, 10.1016/0092-8674(91)90261-V Van Obberghen-Schilling, 1995, Eur. J. Med. Chem., 30S, 117, 10.1016/S0223-5234(23)00118-6 Dennington, 1994, Clin. Exp. Pharmacol. Physiol., 21, 349, 10.1111/j.1440-1681.1994.tb02527.x Coughlin, 1993, Thromb. Haemostasis, 66, 184 Coughlin, 1994, Trends Cardiovasc. Med., 4, 77, 10.1016/1050-1738(94)90013-2 Ogletree, 1994, Persp. Drug Discovery Des., 1, 527, 10.1007/BF02171864 Nystedt, 1994, 91, 9208 Nystedt, 1995, Eur. J. Biochem., 232, 84, 10.1111/j.1432-1033.1995.tb20784.x Nystedt, 1995, J. Biol. Chem., 270, 5950, 10.1074/jbc.270.11.5950 Ishihara, 1997, Nature, 386, 502, 10.1038/386502a0 Xu, 1998, 95, 6642 Kahn, 1998, Nature, 394, 690, 10.1038/29325 Scarborough, 1992, J. Biol. Chem., 267, 13146, 10.1016/S0021-9258(18)42184-9 Hui, 1992, Biochem. Biophys. Res. Commun., 184, 790, 10.1016/0006-291X(92)90659-9 Sabo, 1992, Biochem. Biophys. Res. Commun., 188, 604, 10.1016/0006-291X(92)91099-C Chao, 1992, Biochemistry, 31, 6175, 10.1021/bi00142a001 Vassallo, 1992, J. Biol. Chem., 267, 6081, 10.1016/S0021-9258(18)42664-6 Feng, 1995, J. Med. Chem., 38, 4125, 10.1021/jm00020a029 Natarajan, 1995, Int. J. Peptide Protein Res., 45, 145, 10.1111/j.1399-3011.1995.tb01033.x Seiler, 1996, Mol. Pharmacol., 49, 190 Nose, 1993, Biochem. Biophys. Res. Commun., 193, 694, 10.1006/bbrc.1993.1680 Hoekstra, 1998, Bioorg. Med. Chem. Lett., 8, 649, 10.1016/S0960-894X(98)00292-3 Fields, 1990, Int. J. Pept. Protein Res., 35, 161, 10.1111/j.1399-3011.1990.tb00939.x Atherton, 1981, J. Chem. Soc., Perkin Trans. 1, 538, 10.1039/P19810000538 Penke, 1987, J. Org. Chem., 52, 1197, 10.1021/jo00383a004 Greco, 1996, Bioorg. Med. Chem. Lett., 6, 2947, 10.1016/S0960-894X(96)00554-9 Hoekstra, 1995, J. Med. Chem., 38, 1582, 10.1021/jm00010a002 Bernatowitz, 1996, J. Med. Chem., 39, 4879, 10.1021/jm960455s