Heme binding site in apomyoglobin may be effectively targeted with small molecules to control aggregation
Tài liệu tham khảo
Amijee, 2009, The quest for small molecules as amyloid inhibiting therapies for Alzheimer's disease, Journal of Alzheimer's Disease, 17, 33, 10.3233/JAD-2009-1044
Banks, 1995, Monitoring of a conjugation reaction between fluorescein isothiocyanate and myoglobin by capillary zone electrophoresis, Journal of Chromatography A, 693, 145, 10.1016/0021-9673(94)01110-Z
Bhak, 2009, Mechanism of amyloidogenesis: nucleation-dependent fibrillation versus double-concerted fibrillation, BMB Reports, 42, 541, 10.5483/BMBRep.2009.42.9.541
Bismuto, 1996, Pressure-induced perturbation of apomyoglobin structure: fluorescence studies on native and acidic compact forms, Biochemistry, 35, 1173, 10.1021/bi951163g
Bucciantini, 2002, Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases, Nature, 416, 507, 10.1038/416507a
Calloni, 2005, Investigating the effects of mutations on protein aggregation in the cell, Journal of Biological Chemistry, 280, 10607, 10.1074/jbc.M412951200
Chiti, 2002, Studies of the aggregation of mutant proteins in vitro provide insights into the genetics of amyloid diseases, Proceedings of the National Academy of Sciences of the United States of America, 99, 16419, 10.1073/pnas.212527999
Chiti, 2006, Protein misfolding, functional amyloid, and human disease, Annual Review of Biochemistry, 75, 333, 10.1146/annurev.biochem.75.101304.123901
de Groot, 2005, Amyloid fibril formation by bovine cytochrome c, SPECTROSCOPY – OTTAWA THEN AMSTERDAM, 19, 199
Dumetz, 2008, Effects of pH on protein–protein interactions and implications for protein phase behavior, Biochimica et Biophysica Acta, 1784, 600, 10.1016/j.bbapap.2007.12.016
Ebrahim-Habibi, 2010, Fibrillation of alpha-lactalbumin: effect of crocin and safranal, two natural small molecules from Crocus sativus, Biopolymers, 93, 854, 10.1002/bip.21477
Ebrahim-Habibi, 2010, Protein–protein interactions leading to aggregation: perspectives on mechanism, significance and control, Journal of the Iranian Chemical Society, 7, 521, 10.1007/BF03246041
Es-haghi, 2012, Amyloid fibrillation in native and chemically-modified forms of carbonic anhydrase. II: role of surface hydrophobicity, Biochimica et Biophysica Acta (BBA) – Proteins & Proteomics, 1824, 468, 10.1016/j.bbapap.2011.12.010
Fandrich, 2001, Amyloid fibrils from muscle myoglobin, Nature, 410, 165, 10.1038/35065514
Fandrich, 2003, Myoglobin forms amyloid fibrils by association of unfolded polypeptide segments, Proceedings of the National Academy of Sciences of the United States of America, 100, 15463, 10.1073/pnas.0303758100
Fandrich, 2006, Apomyoglobin reveals a random-nucleation mechanism in amyloid protofibril formation, Acta Histochemica, 108, 215, 10.1016/j.acthis.2006.03.012
Fee, 1975, The behavior of holo- and apo-forms of bovine superoxide dismutase at low pH, Biochimica et Biophysica Acta, 412, 26, 10.1016/0005-2795(75)90336-0
Fink, 1998, Discrete intermediates versus molten globule models for protein folding: characterization of partially folded intermediates of apomyoglobin, Folding and Design, 3, 19, 10.1016/S1359-0278(98)00005-4
Frare, 2004, A highly amyloidogenic region of hen lysozyme, Journal of Molecular Biology, 340, 1153, 10.1016/j.jmb.2004.05.056
Gasiorowski, 2011, Flavones from root of Scutellaria baicalensis Georgi: drugs of the future in neurodegeneration?, CNS & Neurological Disorders – Drug Targets, 10, 184, 10.2174/187152711794480384
Goers, 2002, Conformational prerequisites for alpha-lactalbumin fibrillation, Biochemistry, 41, 12546, 10.1021/bi0262698
Guagliardi, 1995, Prevention of in vitro protein thermal aggregation by the Sulfolobus solfataricus chaperonin. Evidence for nonequivalent binding surfaces on the chaperonin molecule, Journal of Biological Chemistry, 270, 28126, 10.1074/jbc.270.47.28126
Guijarro, 1998, Amyloid fibril formation by an SH3 domain, Proceedings of the National Academy of Sciences of the United States of America, 95, 4224, 10.1073/pnas.95.8.4224
Iannuzzi, 2007, Heme binding inhibits the fibrillization of amyloidogenic apomyoglobin and determines lack of aggregate cytotoxicity, Protein Science, 16, 507, 10.1110/ps.062471107
Infusini, 2012, Resolution of the effects induced by W→F substitutions on the conformation and dynamics of the amyloid-forming apomyoglobin mutant W7FW14F, European Biophysics Journal, 41, 615, 10.1007/s00249-012-0829-1
Jamin, 2005, The folding process of apomyoglobin, Protein and Peptide Letters, 12, 229, 10.2174/0929866053587174
Ji, 2008, The effect of heme on the conformational stability of micro-myoglobin, The FEBS Journal, 275, 89, 10.1111/j.1742-4658.2007.06176.x
Jiang, 2012, Aggregation pathways of the amyloid-beta(1–42) peptide depend on its colloidal stability and ordered beta-sheet stacking, Langmuir, 10.1021/la3021436
Kad, 2003, Hierarchical assembly of beta2-microglobulin amyloid in vitro revealed by atomic force microscopy, Journal of Molecular Biology, 330, 785, 10.1016/S0022-2836(03)00583-7
Ladiwala, 2010, Resveratrol selectively remodels soluble oligomers and fibrils of amyloid Abeta into off-pathway conformers, Journal of Biological Chemistry, 285, 24228, 10.1074/jbc.M110.133108
Ladiwala, 2011, Aromatic small molecules remodel toxic soluble oligomers of amyloid beta through three independent pathways, Journal of Biological Chemistry, 286, 3209, 10.1074/jbc.M110.173856
Lashuel, 2002, Neurodegenerative disease: amyloid pores from pathogenic mutations, Nature, 418, 291, 10.1038/418291a
Lebeau, 2001, Baicalein protects cortical neurons from beta-amyloid (25–35) induced toxicity, Neuroreport, 12, 2199, 10.1097/00001756-200107200-00031
Li, 2001, Only the reduced conformer of alpha-lactalbumin is inducible to aggregation by protein aggregates, Journal of Biochemistry, 129, 821, 10.1093/oxfordjournals.jbchem.a002925
Lin, 2001, Amyloid beta protein forms ion channels: implications for Alzheimer's disease pathophysiology, FASEB Journal, 15, 2433, 10.1096/fj.01-0377com
Mei, 1992, Denaturation of human Cu/Zn superoxide dismutase by guanidine hydrochloride: a dynamic fluorescence study, Biochemistry, 31, 7224, 10.1021/bi00147a003
Meratan, 2011, Membrane integrity and amyloid cytotoxicity: a model study involving mitochondria and lysozyme fibrillation products, Journal of Molecular Biology, 409, 826, 10.1016/j.jmb.2011.04.045
Meratan, 2012, Mitochondrial membrane permeabilization upon interaction with lysozyme fibrillation products: role of mitochondrial heterogeneity, Biochimica et Biophysica Acta, 1818, 2149, 10.1016/j.bbamem.2012.04.020
Morshedi, 2010, Chemical modification of lysine residues in lysozyme may dramatically influence its amyloid fibrillation, Biochimica et Biophysica Acta, 1804, 714, 10.1016/j.bbapap.2009.11.012
Nilsberth, 2001, The ‘Arctic’ APP mutation (E693G) causes Alzheimer's disease by enhanced Abeta protofibril formation, Nature Neuroscience, 4, 887, 10.1038/nn0901-887
Nilsson, 2004, Techniques to study amyloid fibril formation in vitro, Methods, 34, 151, 10.1016/j.ymeth.2004.03.012
Oztug Durer, 2009, Loss of metal ions, disulfide reduction and mutations related to familial ALS promote formation of amyloid-like aggregates from superoxide dismutase, PLoS ONE, 4, e5004, 10.1371/journal.pone.0005004
Ortore, 2011, Time-resolved small-angle X-ray scattering study of the early stage of amyloid formation of an apomyoglobin mutant, Physical Review E: Statistical, Nonlinear, and Soft Matter Physics, 84, 061904, 10.1103/PhysRevE.84.061904
Paulikova, 1998, The effect of heparin and pentosan polysulfate on the thermal stability of yeast alcohol dehydrogenase, Biochemistry and Molecular Biology International, 46, 887
Pertinhez, 2001, Amyloid fibril formation by a helical cytochrome, FEBS Letters, 495, 184, 10.1016/S0014-5793(01)02384-5
Picotti, 2007, Amyloid fibril formation and disaggregation of fragment 1–29 of apomyoglobin: insights into the effect of pH on protein fibrillogenesis, Journal of Molecular Biology, 367, 1237, 10.1016/j.jmb.2007.01.072
Polverini, 2006, Molten globule formation in apomyoglobin monitored by the fluorescent probe Nile Red, Biochemistry, 45, 5111, 10.1021/bi051905y
Qin, 2007, Structural characterization of the partially folded intermediates of an immunoglobulin light chain leading to amyloid fibrillation and amorphous aggregation, Biochemistry, 46, 3521, 10.1021/bi061716v
Qiu, 2008, ArHsp21, a developmentally regulated small heat-shock protein synthesized in diapausing embryos of Artemia franciscana, Biochemical Journal, 411, 605, 10.1042/BJ20071472
Rafikova, 2003, A mechanism of macroscopic (amorphous) aggregation of the tobacco mosaic virus coat protein, International Journal of Biochemistry and Cell Biology, 35, 1452, 10.1016/S1357-2725(03)00106-7
Re, 2010, Beta amyloid aggregation inhibitors: small molecules as candidate drugs for therapy of Alzheimer's disease, Current Medicinal Chemistry, 17, 2990, 10.2174/092986710791959729
Rezaei-Ghaleh, 2007, Effect of polyamines on the structure, thermal stability and 2,2,2-trifluoroethanol-induced aggregation of alpha-chymotrypsin, International Journal of Biological Macromolecules, 41, 597, 10.1016/j.ijbiomac.2007.07.018
Rezaei-Ghaleh, 2007, Role of electrostatic interactions in 2,2,2-trifluoroethanol-induced structural changes and aggregation of alpha-chymotrypsin, Archives of Biochemistry and Biophysics, 457, 160, 10.1016/j.abb.2006.10.031
Rezaei-Ghaleh, 2011, Effect of zinc binding on beta-amyloid structure and dynamics: implications for Abeta aggregation, Biophysical Journal, 101, 1202, 10.1016/j.bpj.2011.06.062
Riviere, 2009, The polyphenol piceid destabilizes preformed amyloid fibrils and oligomers in vitro: hypothesis on possible molecular mechanisms, Neurochemical Research, 34, 1120, 10.1007/s11064-008-9883-6
Sabbaghian, 2011, Prevention of thermal aggregation of an allosteric protein by small molecules: some mechanistic insights, International Journal of Biological Macromolecules, 49, 806, 10.1016/j.ijbiomac.2011.07.016
Sackett, 1987, Nile red as a polarity-sensitive fluorescent probe of hydrophobic protein surfaces, Analytical Biochemistry, 167, 228, 10.1016/0003-2697(87)90157-6
Sirangelo, 2004, Fibrillogenesis and cytotoxic activity of the amyloid-forming apomyoglobin mutant W7FW14F, Journal of Biological Chemistry, 279, 13183, 10.1074/jbc.M308207200
Sirangelo, 2009, W7FW14F apomyoglobin amyloid aggregates-mediated apoptosis is due to oxidative stress and AKT inactivation caused by Ras and Rac, Journal of Cellular Physiology, 221, 412, 10.1002/jcp.21871
Sirangelo, 2010, Inhibition of aggregate formation as therapeutic target in protein misfolding diseases: effect of tetracycline and trehalose, Expert Opinion on Therapeutic Targets, 14, 1311, 10.1517/14728222.2010.531012
Sood, 2011, Disassembly of preformed amyloid beta fibrils by small organofluorine molecules, Bioorganic and Medicinal Chemistry Letters, 21, 2044, 10.1016/j.bmcl.2011.02.012
Stryer, 1965, The interaction of a naphthalene dye with apomyoglobin and apohemoglobin. A fluorescent probe of non-polar binding sites, Journal of Molecular Biology, 13, 482, 10.1016/S0022-2836(65)80111-5
Tcherkasskaya, 1999, Molten globule versus variety of intermediates: influence of anions on pH-denatured apomyoglobin, FEBS Letters, 455, 325, 10.1016/S0014-5793(99)00792-9
Teale, 1959, Cleavage of the haem-protein link by acid methylethylketone, Biochimica et Biophysica Acta, 35, 543, 10.1016/0006-3002(59)90407-X
Thapa, 2011, Biflavonoids are superior to monoflavonoids in inhibiting amyloid-beta toxicity and fibrillogenesis via accumulation of nontoxic oligomer-like structures, Biochemistry, 50, 2445, 10.1021/bi101731d
Trott, 2010, AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading, Journal of Computational Chemistry, 31, 455
Tyedmers, 2010, Cellular strategies for controlling protein aggregation, Nature Reviews Molecular Cell Biology, 11, 777, 10.1038/nrm2993
Uversky, 2001, Evidence for a partially folded intermediate in alpha-synuclein fibril formation, Journal of Biological Chemistry, 276, 10737, 10.1074/jbc.M010907200
Veprintsev, 1997, Cooperative thermal transitions of bovine and human apo-alpha-lactalbumins: evidence for a new intermediate state, FEBS Letters, 412, 625, 10.1016/S0014-5793(97)00841-7
Vetri, 2007, Amyloid fibrils formation and amorphous aggregation in concanavalin A, Biophysical Chemistry, 125, 184, 10.1016/j.bpc.2006.07.012
Vetri, 2007, Thermal aggregation of bovine serum albumin at different pH: comparison with human serum albumin, European Biophysics Journal, 36, 717, 10.1007/s00249-007-0196-5
Vetri, 2011, Bovine serum albumin protofibril-like aggregates formation: solo but not simple mechanism, Archives of Biochemistry and Biophysics, 508, 13, 10.1016/j.abb.2011.01.024
Vilasi, 2008, Effect of trehalose on W7FW14F apomyoglobin and insulin fibrillization: new insight into inhibition activity, Biochemistry, 47, 1789, 10.1021/bi701530w
Vilasi, 2011, Heparin induces harmless fibril formation in amyloidogenic W7FW14F apomyoglobin and amyloid aggregation in wild-type protein in vitro, PLoS ONE, 6, e22076, 10.1371/journal.pone.0022076
Weise, 2010, Interaction of hIAPP with model raft membranes and pancreatic beta-cells: cytotoxicity of hIAPP oligomers, ChemBioChem, 11, 1280, 10.1002/cbic.201000039
Woods, 2011, Ligand binding to distinct states diverts aggregation of an amyloid-forming protein, Nature Chemical Biology, 7, 730, 10.1038/nchembio.635
Zhu, 2007, Flavonoids possess neuroprotective effects on cultured pheochromocytoma PC12 cells: a comparison of different flavonoids in activating estrogenic effect and in preventing beta-amyloid-induced cell death, Journal of Agricultural and Food Chemistry, 55, 2438, 10.1021/jf063299z