Hematopoietic chemoprotection by drug resistance gene transfer

Cournoyer, 1993, Gene therapy of the immune system, Annu Rev Immunol, 11, 297, 10.1146/annurev.iy.11.040193.001501 Bertino, 1990, Turning the tables — making normal marrow resistant to chemotherapy, J Natl Cancer Inst, 82, 1234, 10.1093/jnci/82.15.1234 Isola, 1986, Systemic resistance to methotrexate in transgenic mice carrying a mutant dihydrofolate reductase gene, 83, 9621 Galski, 1989, Expression of multidrug resistance cDNA (MDR1) in the bone marrow of transgenic mice: resistance to daunomycin-induced leukopenia, Mol Cell Biol, 9, 4357, 10.1128/MCB.9.10.4357 Corey, 1990, Serial transplantation of methotrexate-resistant bone marrow: protection of murine recipients from drug toxicity by progeny of transduced stem cells, Blood, 75, 337, 10.1182/blood.V75.2.337.337 Sorrentino, 1992, Selection of drug-resistant bone marrow cells in vivo after retroviral transfer of human MDR 1, Science, 257, 99, 10.1126/science.1352414 1994, Hum Gene Ther, 5, 1537, 10.1089/hum.1994.5.12-1537 Bienzle, 1994, Gene transfer into hematopoietic stem cells: long term maintenance of in vitro activated progenitors without marrow ablation, 91, 350 Bodine, 1994, Efficient retrovirus transduction of mouse pluripotent hematopoietic stem cells mobilized into the peripheral blood by treatment with granulocyte colony-stimulating factor and stem cell factor, Blood, 84, 1482, 10.1182/blood.V84.5.1482.1482 Szilvassy, 1989, Retrovirus-mediated gene transfer to purified hemopoietic stem cells with long-term lymphomyelopoietic repopulating ability, 86, 8798 Culver, 1992, In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors, Science, 256, 1550, 10.1126/science.1317968 Bodell, 1986, Increased repair of O6-alkylguanine DNA adducts in gliomaderived human cells resistant to cytotoxic, Carcinogenesis, 7, 879, 10.1093/carcin/7.6.879 Dumenco, 1989, Increase in nitrosourea resistance in mammalian cells by retrovirally mediated gene transfer of bacterial O6-alkylguanine DNA alkyltransferase, Cancer Res, 49, 6044 Gerson, 1992, Modulation of nitrosourea resistance in human colon cancer by O6-methylguanine, Biochem Pharmacol, 443, 1101, 10.1016/0006-2952(92)90618-S Yoshida, 1993, Enhanced transcription of the cytosolic ALDH gene in cyclophosphamide resistant human carcinoma cells, Adv Exp Med Biol, 328, 63, 10.1007/978-1-4615-2904-0_8 Sreerama, 1993, Overexpression of polycyclic aromatic hydrocarbon-mediated induction of an apparently novel class 3 aldehyde dehydrogenase in human breast adenocarcinoma cells and its relationship to oxazaphosphorinespecific acquired resistance, Adv Exp Med Biol, 328, 99, 10.1007/978-1-4615-2904-0_12 Bunting, 1994, Oxazaphosphorine-specific resistance in human MCF-7 breast carcinoma cell lines expressing transfected rat class 3 aldehyde dehydrogenase, J Biol Chem, 269, 23197, 10.1016/S0021-9258(17)31639-3 Batist, 1986, Overexpression of a novel anionic glutathione transferase in multidrug-resistant human breast cancer cells, J Biol Chem, 261, 15544, 10.1016/S0021-9258(18)66748-1 Wolf, 1987, Cellular heterogeneity and drug resistance in two ovarian adenocarcinoma cell lines derived from a single patient, Int J Cancer, 39, 695, 10.1002/ijc.2910390607 Buller, 1987, Glutathione-S-transferase in nitrogen mustard-resistant and sensitive cell lines, Molec Pharmacol, 31, 575 Robson, 1987, Reduced levels of drug-induced DNA cross linking in nitrogen mustard-resistant Chinese hamster ovary cells expressing elevated glutathioneS-transferase activity, Cancer Res, 47, 6022 Lewis, 1988, Amplification and increased expression of alpha class glutathione-S-transferaseencoding genes associated with resistance to nitrogen mustards, 85, 8511 Smith, 1989, Denitrosation of 1,3-bis(chloroethyl)-1-nitrosourea by class mu glutathione transferases and its role in cellular resistance in rat brain tumor cells, Cancer Res, 49, 2621 Schecter, 1991, In vitro and in vivo mechanisms of drug resistance in a rat mammary carcinoma model, Cancer Res, 51, 1434 Schisselbauer, 1990, Characterization of lymphocyte glutathione S-transferase isozymes in chronic lymphocytic leukemia (CLL), Cancer Res, 50, 3569 Tew, 1988, Ethacrynic acid and piriprost as enhancers of cytotoxicity in drug-resistant and -sensitive cell lines, Cancer Res, 48, 3622 Clapper, 1990, Sensitization of human colon tumor xenografts to L-phenylalanine mustard using ethacrynic acid, J Cell Pharmacol, 1, 71 Black, 1989, Expression of human glutathione transferases in S. cerevisiae confers resistance to alkylating agents and chlorambucil, 30, 515 Miyasaki, 1990, Drug resistance to cis-diamminedichloroplatinum (II) in Chinese hamster ovary cell lines transfected with glutathione S-transferase pi gene, Biochem Biophys Res Commun, 166, 1358, 10.1016/0006-291X(90)91016-L Puchalski, 1990, Expression of recombinant glutathione S-transferase pi, Ya or Ybl confers resistance to alkylating agents, 87, 2443 Schecter, 1992, Glutathione S-transferase in chemotherapy resistance and in carcinogenesis, Biochem Cell Biol, 70, 349, 10.1139/o92-054 Schecter, 1993, Expression of rat glutathione S-transferase Yc complementary DNA in rat mammary carcinoma cells: impact upon alkylator-induced toxicity, Cancer Res, 53, 4900 Moscow, 1989, Elevation of pi class glutathione S-transferase activity in human breast cancer cells by transfection of the GST pi gene and its effect on sensitivity to toxins, Molec Pharmacol, 36, 22 Moscow, 1989, Expression of anionic glutathione-S-tranferase and P-glycoprotein genes in human tissues and tumors, Cancer Res, 49, 1422 Leyland-Jones, 1991, Antineoplastic drug sensitivity of human MCF-7 breast cancer cells stably transfected with a human a class glutathione S-transferase gene, Cancer Res, 51, 587 Morrow, 1993, Antineoplastic drug resistance and breast cancer, Ann NY Acad Sci, 698, 289, 10.1111/j.1749-6632.1993.tb17220.x Waxman, 1990, Glutathione S-transferases: role in alkylating agent resistance and possible target for modulation chemotherapy — a review, Cancer Res, 50, 6449 Mannervick, 1985, The isoenzymes of glutathione transferase, Adv Enzymol, 57, 357 Scarpa, 1991, Characterization of recombinant helper retroviruses from Moloney-based vectors in ecotropic and amphotropic packaging cell lines, Virology, 180, 849, 10.1016/0042-6822(91)90105-K Cournoyer, 1991, Gene transfer of adenosine deaminase into primitive human hematopoietic progenitor cells, Hum Gene Ther, 2, 203, 10.1089/hum.1991.2.3-203 Greenbaum, 1994, Retrovirus-mediated gene transfer of rat glutathione S-transferase Yc confers alkylating drug resistance in NIH 3T3 mouse fibroblasts, Cancer Res, 54, 4442 Tormey, 1984, Aggressive systemic therapy for metastatic breast cancer Peters, 1985, The rationale for high-dose chemotherapy with autologous bone marrow support in treating breast cancer, 189 Chabner, 1989, Clinical pharmacology of cancer chemotherapy Schecter, 1994, Glutathione S-transferase expression in mammary tumors and bone marrow cells, Cell Pharmacol, 1, 153 Tew, 1994, Glutathione-associated enzymes in anticancer drug resistance, Cancer Res, 54, 4313 Létourneau, 1996, Retrovirus-mediated gene transfer of rat glutathione S-transferase Yc confers in vitro resistance to alkylating agents in human leukemia cells and in primary mouse hematopoietic progenitor cells, Hum Gene Ther, 10.1089/hum.1996.7.7-831 Godwin, 1992, High resistance to cisplatin in human ovarian cancer cell lines is associated with marked increase of glutathione synthesis, 89, 3070 Mulcahy, 1994, Upregulation of gamma-glutamylcysteine synthetase activity in melphalan-resistant human multiple myeloma cells expressing increased glutathione levels, Cancer Chemother Pharmacol, 34, 67, 10.1007/BF00686114 Mulcahy, 1994, Transcriptional up-regulation of gammaglutamyl cysteine synthetase gene expression in melphalan-resistant human prostate carcinoma cells, Molec Pharmacol, 46, 909 Yan, 1990, Amino acid sequence of rat γ-glutamylcysteine synthetase, J Biol Chem, 265, 1588, 10.1016/S0021-9258(19)40057-4 Gipp, 1992, Cloning and nucleotide sequence of a full-length cDNA for human liver γ-glutamylcysteine synthetase, Biochem Biophys Res Commun, 185, 29, 10.1016/S0006-291X(05)80950-7 Huang, 1993, Amino acid sequence and function of the light subunit of rat kidney γ-glutamylcysteine synthetase, J Biol Chem, 268, 20578, 10.1016/S0021-9258(20)80764-9 Gipp, 1995, Cloning and sequencing of the cDNA for the light subunit of human liver γ-glutamylcysteine synthetase and relative mRNA levels for heavy and light subunits in normal human tissues, Biol Biophys Res Comm, 206, 589